Motif ID: Meis1

Z-value: 0.796


Transcription factors associated with Meis1:

Gene SymbolEntrez IDGene Name
Meis1 ENSMUSG00000020160.12 Meis1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis1mm10_v2_chr11_-_19018714_19018828-0.085.0e-01Click!


Activity profile for motif Meis1.

activity profile for motif Meis1


Sorted Z-values histogram for motif Meis1

Sorted Z-values for motif Meis1



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 9.148 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr9_+_87022014 3.924 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr3_+_125404292 3.319 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr6_-_136941494 2.642 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr7_-_143460989 2.447 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr9_-_107985863 2.431 ENSMUST00000048568.4
Fam212a
family with sequence similarity 212, member A
chr2_-_168767136 2.420 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr3_+_134828993 2.286 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr9_+_78051938 2.186 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr8_+_127064022 2.157 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr8_+_127064107 2.133 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr4_-_46566432 2.067 ENSMUST00000030021.7
ENSMUST00000107757.1
Coro2a

coronin, actin binding protein 2A

chr1_-_65051119 1.955 ENSMUST00000161960.1
ENSMUST00000087359.5
Cryge

crystallin, gamma E

chr2_+_93642307 1.914 ENSMUST00000042078.3
ENSMUST00000111254.1
Alx4

aristaless-like homeobox 4

chr1_-_138842429 1.912 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr17_-_23844155 1.900 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
Prss41


protease, serine, 41


chr4_+_101507947 1.895 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr10_+_69208546 1.867 ENSMUST00000164034.1
Rhobtb1
Rho-related BTB domain containing 1
chr11_+_44617310 1.815 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr6_-_99632376 1.789 ENSMUST00000176255.1
Gm20696
predicted gene 20696

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 9.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.7 4.3 GO:0003383 apical constriction(GO:0003383)
0.2 4.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 3.9 GO:0046677 response to antibiotic(GO:0046677)
0.1 2.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 2.7 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.5 2.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 2.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 2.4 GO:0060065 uterus development(GO:0060065)
0.0 2.4 GO:0021915 neural tube development(GO:0021915)
0.2 2.3 GO:0007379 segment specification(GO:0007379)
0.4 2.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 2.2 GO:0010950 positive regulation of endopeptidase activity(GO:0010950)
0.0 2.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.4 1.9 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 1.9 GO:0030259 lipid glycosylation(GO:0030259)
0.3 1.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 1.9 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.6 1.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) phosphate ion transmembrane transport(GO:0035435)
0.4 1.8 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 5.2 GO:0000792 heterochromatin(GO:0000792)
0.5 4.3 GO:0033269 internode region of axon(GO:0033269)
0.1 3.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.8 GO:0044298 cell body membrane(GO:0044298)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 1.8 GO:0008537 proteasome activator complex(GO:0008537)
0.3 1.8 GO:0045179 apical cortex(GO:0045179)
0.5 1.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.1 1.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 19.0 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.6 5.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 4.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 3.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 3.3 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.4 2.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 2.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.6 1.8 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 1.8 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.2 1.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.8 GO:0043274 phospholipase binding(GO:0043274)
0.6 1.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.6 GO:0020037 heme binding(GO:0020037)