Motif ID: Meis2

Z-value: 1.271


Transcription factors associated with Meis2:

Gene SymbolEntrez IDGene Name
Meis2 ENSMUSG00000027210.14 Meis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis2mm10_v2_chr2_-_116065798_1160658530.473.9e-05Click!


Activity profile for motif Meis2.

activity profile for motif Meis2


Sorted Z-values histogram for motif Meis2

Sorted Z-values for motif Meis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_194619815 14.675 ENSMUST00000027952.5
Plxna2
plexin A2
chr5_-_100159261 13.108 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr19_+_42247544 12.457 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr9_-_121495678 11.040 ENSMUST00000035120.4
Cck
cholecystokinin
chr4_+_42922253 10.536 ENSMUST00000139100.1
N28178
expressed sequence N28178
chr18_+_36939178 9.952 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr3_-_82074639 9.467 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr17_+_8924109 9.165 ENSMUST00000149440.1
Pde10a
phosphodiesterase 10A
chr7_+_48959089 8.841 ENSMUST00000183659.1
Nav2
neuron navigator 2
chr19_-_57197435 8.833 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr3_-_107518001 8.807 ENSMUST00000169449.1
ENSMUST00000029499.8
Slc6a17

solute carrier family 6 (neurotransmitter transporter), member 17

chr19_-_57197377 8.709 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr8_+_120114144 8.642 ENSMUST00000108948.1
ENSMUST00000034281.6
ENSMUST00000108951.1
6430548M08Rik


RIKEN cDNA 6430548M08 gene


chr19_-_57197496 8.570 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197556 8.562 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr4_+_128058962 8.465 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr9_-_86880414 8.302 ENSMUST00000074501.5
ENSMUST00000098495.3
ENSMUST00000074468.6
ENSMUST00000036347.6
Snap91



synaptosomal-associated protein 91



chr2_+_71981184 7.737 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr12_-_24493656 7.456 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr2_+_158667119 7.308 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 157 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 19.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.4 16.2 GO:0006376 mRNA splice site selection(GO:0006376)
1.5 14.7 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
3.1 12.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 11.4 GO:0008643 carbohydrate transport(GO:0008643)
1.1 10.9 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.5 10.2 GO:0048268 clathrin coat assembly(GO:0048268)
3.2 9.6 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
1.6 9.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 9.5 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.5 9.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.5 9.0 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.4 9.0 GO:0007020 microtubule nucleation(GO:0007020)
0.1 8.9 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
2.2 8.8 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
1.8 8.8 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.9 8.3 GO:0018095 protein polyglutamylation(GO:0018095)
1.0 7.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
2.6 7.7 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.8 7.7 GO:0098907 regulation of SA node cell action potential(GO:0098907)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 27.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 19.6 GO:0097060 synaptic membrane(GO:0097060)
0.1 14.9 GO:0008021 synaptic vesicle(GO:0008021)
1.3 14.7 GO:0002116 semaphorin receptor complex(GO:0002116)
2.7 13.3 GO:0044316 cone cell pedicle(GO:0044316)
0.1 12.7 GO:0043204 perikaryon(GO:0043204)
0.0 11.7 GO:0070062 extracellular exosome(GO:0070062)
0.8 11.0 GO:0043203 axon hillock(GO:0043203)
0.1 10.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 10.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 9.8 GO:0005794 Golgi apparatus(GO:0005794)
1.9 9.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.8 8.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 8.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 7.9 GO:0001891 phagocytic cup(GO:0001891)
0.8 7.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.6 7.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 7.0 GO:0031931 TORC1 complex(GO:0031931)
0.4 7.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 6.9 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 23.4 GO:0003779 actin binding(GO:0003779)
0.8 16.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.0 14.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.7 12.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
2.4 9.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
1.9 9.6 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 9.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.3 9.5 GO:0030552 cAMP binding(GO:0030552)
0.1 9.3 GO:0005125 cytokine activity(GO:0005125)
0.5 9.2 GO:0030553 cGMP binding(GO:0030553)
2.2 9.0 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.6 8.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.9 8.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 7.5 GO:0008201 heparin binding(GO:0008201)
0.8 7.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 7.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.6 7.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.4 6.8 GO:0050321 tau-protein kinase activity(GO:0050321)
1.3 6.7 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 6.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)