Motif ID: Meox2
Z-value: 0.666
Transcription factors associated with Meox2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Meox2 | ENSMUSG00000036144.5 | Meox2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Meox2 | mm10_v2_chr12_+_37108533_37108546 | 0.26 | 2.7e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.3 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.8 | 2.5 | GO:0008228 | opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.6 | 2.2 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.4 | 1.4 | GO:0032788 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
| 0.3 | 1.0 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
| 0.3 | 1.4 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.3 | 2.4 | GO:0000022 | mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256) |
| 0.3 | 1.9 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.3 | 0.9 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
| 0.3 | 1.0 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139) |
| 0.2 | 3.7 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
| 0.2 | 0.6 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
| 0.2 | 0.9 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.2 | 1.3 | GO:1901970 | positive regulation of mitotic sister chromatid separation(GO:1901970) |
| 0.2 | 0.8 | GO:0030091 | protein repair(GO:0030091) |
| 0.2 | 2.9 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.2 | 0.5 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
| 0.1 | 1.5 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.1 | 0.8 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.1 | 4.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 1.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 0.7 | GO:0010528 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
| 0.1 | 2.7 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.1 | 0.3 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.1 | 0.3 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
| 0.1 | 0.5 | GO:0033762 | response to glucagon(GO:0033762) |
| 0.1 | 0.7 | GO:0051775 | response to redox state(GO:0051775) |
| 0.1 | 0.3 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.1 | 8.9 | GO:0045580 | regulation of T cell differentiation(GO:0045580) |
| 0.1 | 1.6 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.1 | 1.6 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.1 | 2.1 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
| 0.1 | 0.9 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 0.2 | GO:0007128 | meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764) |
| 0.1 | 0.5 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.1 | 1.3 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
| 0.1 | 0.5 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) |
| 0.1 | 0.2 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 0.0 | 1.4 | GO:0072698 | protein localization to microtubule cytoskeleton(GO:0072698) |
| 0.0 | 0.1 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.0 | 0.9 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.6 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 2.0 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 1.0 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.0 | 0.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.2 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.0 | 0.4 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.0 | 0.2 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.0 | 0.8 | GO:0009225 | nucleotide-sugar metabolic process(GO:0009225) |
| 0.0 | 0.1 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.0 | 0.2 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.0 | 0.1 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.0 | 0.1 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.0 | 0.3 | GO:0001946 | lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303) |
| 0.0 | 0.9 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.7 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 0.5 | 2.4 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.2 | 1.0 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.2 | 0.8 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.2 | 0.8 | GO:0008623 | CHRAC(GO:0008623) |
| 0.1 | 1.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 1.0 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 0.9 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 0.4 | GO:0045275 | respiratory chain complex III(GO:0045275) |
| 0.0 | 3.5 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 0.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.0 | 0.3 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.0 | 0.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 1.5 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 1.0 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 3.3 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 0.4 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 1.6 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 1.2 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.2 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.0 | 2.1 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 2.8 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 1.6 | GO:0005884 | actin filament(GO:0005884) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.7 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.6 | 1.9 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.5 | 2.5 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.2 | 1.0 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.1 | 2.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.8 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
| 0.1 | 3.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 5.1 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 0.3 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.1 | 1.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 0.3 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.1 | 8.0 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 3.3 | GO:0051287 | NAD binding(GO:0051287) |
| 0.1 | 0.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 1.9 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.0 | 1.2 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.7 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 1.0 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 1.5 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.9 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.4 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.1 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.8 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 0.7 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.1 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.0 | 0.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.4 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 3.3 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 1.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
