Motif ID: Meox2

Z-value: 0.666


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_371085460.262.7e-02Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

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Top targets:


Showing 1 to 20 of 147 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_26119811 6.586 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_25980039 6.468 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr14_+_26259109 5.313 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr16_+_42907563 4.733 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr8_-_46294592 3.721 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr13_+_104229366 3.417 ENSMUST00000022227.6
 Cenpk
centromere protein K
chr3_-_98339921 3.339 ENSMUST00000065793.5
 Phgdh
3-phosphoglycerate dehydrogenase
chr8_+_12395287 2.871 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr5_-_62766153 2.792 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_+_75005523 2.667 ENSMUST00000001927.5
 Ltbp1
latent transforming growth factor beta binding protein 1
chr14_+_25979401 2.547 ENSMUST00000173580.1
 Duxbl1
double homeobox B-like 1
chr3_+_66219909 2.453 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr15_-_99651580 2.363 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
 Racgap1




Rac GTPase-activating protein 1




chr14_+_26119173 2.092 ENSMUST00000174564.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 2.092 ENSMUST00000172517.1
 Duxbl3
double homeobox B-like 3
chr3_+_127553462 2.083 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr8_-_4779513 1.952 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr15_-_74752963 1.927 ENSMUST00000023259.8
 Lynx1
Ly6/neurotoxin 1
chr9_-_36726374 1.866 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1


chr10_-_128804353 1.731 ENSMUST00000051011.7
 Tmem198b
transmembrane protein 198b

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.9 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 4.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 3.7 GO:0097154 GABAergic neuron differentiation(GO:0097154)
1.1 3.3 GO:0006566 threonine metabolic process(GO:0006566)
0.2 2.9 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 2.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.8 2.5 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 2.4 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.6 2.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 2.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 2.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.3 1.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.6 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 1.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 1.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4 1.4 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.3 1.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.4 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.2 1.3 GO:1901970 positive regulation of mitotic sister chromatid separation(GO:1901970)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0070469 respiratory chain(GO:0070469)
0.0 3.3 GO:0000776 kinetochore(GO:0000776)
0.0 2.8 GO:0043209 myelin sheath(GO:0043209)
0.9 2.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.5 2.4 GO:0097149 centralspindlin complex(GO:0097149)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 1.5 GO:0005657 replication fork(GO:0005657)
0.1 1.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.2 GO:0000922 spindle pole(GO:0000922)
0.2 1.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 0.8 GO:0008623 CHRAC(GO:0008623)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 5.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 3.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.3 GO:0051287 NAD binding(GO:0051287)
0.0 3.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.7 2.7 GO:0050436 microfibril binding(GO:0050436)
0.5 2.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 1.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 1.9 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.1 1.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 1.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.8 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)