Motif ID: Mga

Z-value: 0.620


Transcription factors associated with Mga:

Gene SymbolEntrez IDGene Name
Mga ENSMUSG00000033943.9 Mga

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_1198973050.335.5e-03Click!


Activity profile for motif Mga.

activity profile for motif Mga


Sorted Z-values histogram for motif Mga

Sorted Z-values for motif Mga



Network of associatons between targets according to the STRING database.



First level regulatory network of Mga

PNG image of the network

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Top targets:


Showing 1 to 20 of 81 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66801577 5.533 ENSMUST00000168589.1
 Sla
src-like adaptor
chr15_-_43869993 4.369 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr4_+_43381979 4.288 ENSMUST00000035645.5
ENSMUST00000144911.1
 Rusc2

RUN and SH3 domain containing 2

chr6_-_41636389 3.960 ENSMUST00000031902.5
 Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr8_+_12984246 3.775 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
 Mcf2l


mcf.2 transforming sequence-like


chr11_+_49203465 3.327 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
 Zfp62


zinc finger protein 62


chr9_+_57940104 3.224 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr11_+_49203285 3.051 ENSMUST00000109198.1
ENSMUST00000137061.2
 Zfp62

zinc finger protein 62

chr5_-_138619751 2.979 ENSMUST00000085852.4
ENSMUST00000110905.2
 Zfp68

zinc finger protein 68

chr5_-_138619702 2.964 ENSMUST00000063262.4
 Zfp68
zinc finger protein 68
chr10_+_81575257 2.867 ENSMUST00000135211.1
 Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr10_+_81575306 2.754 ENSMUST00000146916.1
 Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr13_+_29016267 2.530 ENSMUST00000140415.1
 A330102I10Rik
RIKEN cDNA A330102I10 gene
chrX_+_35888808 2.427 ENSMUST00000033419.6
 Dock11
dedicator of cytokinesis 11
chr6_-_149188648 2.396 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
 Amn1


antagonist of mitotic exit network 1


chr3_+_13946368 2.386 ENSMUST00000171075.1
ENSMUST00000108372.2
 Ralyl

RALY RNA binding protein-like

chr4_+_95967322 2.370 ENSMUST00000107083.1
 Hook1
hook homolog 1 (Drosophila)
chr11_+_113657375 2.213 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
 Cog1


component of oligomeric golgi complex 1


chr5_-_138619653 2.049 ENSMUST00000129832.1
 Zfp68
zinc finger protein 68
chr5_+_149265035 2.020 ENSMUST00000130144.1
ENSMUST00000071130.3
 Alox5ap

arachidonate 5-lipoxygenase activating protein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.6 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.3 4.0 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.2 3.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.4 3.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 2.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 2.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.7 2.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0 1.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.2 1.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 1.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 1.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.4 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.3 1.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.2 1.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 1.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 1.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.2 1.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 1.1 GO:0036465 synaptic vesicle recycling(GO:0036465)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 4.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 2.4 GO:0070695 FHF complex(GO:0070695)
0.1 2.2 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0097440 apical dendrite(GO:0097440)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 4.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 3.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 3.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.9 GO:0008017 microtubule binding(GO:0008017)
0.3 2.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.4 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.3 1.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 1.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.3 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 1.2 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)