Motif ID: Mga

Z-value: 0.620


Transcription factors associated with Mga:

Gene SymbolEntrez IDGene Name
Mga ENSMUSG00000033943.9 Mga

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_1198973050.335.5e-03Click!


Activity profile for motif Mga.

activity profile for motif Mga


Sorted Z-values histogram for motif Mga

Sorted Z-values for motif Mga



Network of associatons between targets according to the STRING database.



First level regulatory network of Mga

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 5.533 ENSMUST00000168589.1
 Sla
src-like adaptor
chr15_-_43869993 4.369 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr4_+_43381979 4.288 ENSMUST00000035645.5
ENSMUST00000144911.1
 Rusc2

RUN and SH3 domain containing 2

chr6_-_41636389 3.960 ENSMUST00000031902.5
 Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr8_+_12984246 3.775 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
 Mcf2l


mcf.2 transforming sequence-like


chr11_+_49203465 3.327 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
 Zfp62


zinc finger protein 62


chr9_+_57940104 3.224 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr11_+_49203285 3.051 ENSMUST00000109198.1
ENSMUST00000137061.2
 Zfp62

zinc finger protein 62

chr5_-_138619751 2.979 ENSMUST00000085852.4
ENSMUST00000110905.2
 Zfp68

zinc finger protein 68

chr5_-_138619702 2.964 ENSMUST00000063262.4
 Zfp68
zinc finger protein 68
chr10_+_81575257 2.867 ENSMUST00000135211.1
 Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr10_+_81575306 2.754 ENSMUST00000146916.1
 Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr13_+_29016267 2.530 ENSMUST00000140415.1
 A330102I10Rik
RIKEN cDNA A330102I10 gene
chrX_+_35888808 2.427 ENSMUST00000033419.6
 Dock11
dedicator of cytokinesis 11
chr6_-_149188648 2.396 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
 Amn1


antagonist of mitotic exit network 1


chr3_+_13946368 2.386 ENSMUST00000171075.1
ENSMUST00000108372.2
 Ralyl

RALY RNA binding protein-like

chr4_+_95967322 2.370 ENSMUST00000107083.1
 Hook1
hook homolog 1 (Drosophila)
chr11_+_113657375 2.213 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
 Cog1


component of oligomeric golgi complex 1


chr5_-_138619653 2.049 ENSMUST00000129832.1
 Zfp68
zinc finger protein 68
chr5_+_149265035 2.020 ENSMUST00000130144.1
ENSMUST00000071130.3
 Alox5ap

arachidonate 5-lipoxygenase activating protein

chr8_+_3393018 1.949 ENSMUST00000004684.6
ENSMUST00000145394.1
 Arhgef18

rho/rac guanine nucleotide exchange factor (GEF) 18

chr8_+_83165348 1.916 ENSMUST00000034145.4
 Tbc1d9
TBC1 domain family, member 9
chr14_+_64652524 1.615 ENSMUST00000100473.4
 Kif13b
kinesin family member 13B
chr7_-_24316590 1.568 ENSMUST00000108436.1
ENSMUST00000032673.8
 Zfp94

zinc finger protein 94

chr3_+_124321031 1.564 ENSMUST00000058994.4
 Tram1l1
translocation associated membrane protein 1-like 1
chr14_-_52279238 1.398 ENSMUST00000167116.1
ENSMUST00000100631.4
 Rab2b

RAB2B, member RAS oncogene family

chr14_-_55900188 1.339 ENSMUST00000111325.3
 Sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr9_-_85749308 1.313 ENSMUST00000039213.8
 Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr6_-_56923927 1.254 ENSMUST00000031793.5
 Nt5c3
5'-nucleotidase, cytosolic III
chr17_-_32350569 1.252 ENSMUST00000050214.7
 Akap8l
A kinase (PRKA) anchor protein 8-like
chr2_+_83644435 1.239 ENSMUST00000081591.6
 Zc3h15
zinc finger CCCH-type containing 15
chr8_+_3353415 1.197 ENSMUST00000098966.3
 A430078G23Rik
RIKEN cDNA A430078G23 gene
chr2_+_55411790 1.189 ENSMUST00000155997.1
ENSMUST00000128307.1
 Gm14033

predicted gene 14033

chr19_+_47228804 1.185 ENSMUST00000111807.3
 Neurl1a
neuralized homolog 1A (Drosophila)
chr10_+_18055711 1.122 ENSMUST00000154718.1
ENSMUST00000126390.1
ENSMUST00000164556.1
ENSMUST00000150029.1
 Reps1



RalBP1 associated Eps domain containing protein



chr1_+_170214826 1.118 ENSMUST00000159201.1
ENSMUST00000055830.1
 4930500M09Rik

RIKEN cDNA 4930500M09 gene

chr1_+_171419027 1.116 ENSMUST00000171362.1
 Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr3_+_89773562 1.106 ENSMUST00000038356.8
 Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chrX_+_163909132 1.089 ENSMUST00000033734.7
ENSMUST00000112294.2
 Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr14_-_18893623 1.029 ENSMUST00000177259.1
 Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr1_+_75435930 0.997 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
 Gmppa






GDP-mannose pyrophosphorylase A






chr13_-_8870999 0.951 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
 Wdr37


WD repeat domain 37


chr15_+_51877429 0.942 ENSMUST00000137116.2
ENSMUST00000161651.1
ENSMUST00000059599.9
 Utp23


UTP23, small subunit (SSU) processome component, homolog (yeast)


chr4_-_117125618 0.927 ENSMUST00000183310.1
 Btbd19
BTB (POZ) domain containing 19
chr1_+_75436002 0.919 ENSMUST00000131545.1
ENSMUST00000141124.1
 Gmppa

GDP-mannose pyrophosphorylase A

chr16_-_9994921 0.910 ENSMUST00000115835.1
 Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr2_+_144527718 0.806 ENSMUST00000028914.2
ENSMUST00000110017.2
 Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr2_-_129371131 0.796 ENSMUST00000028881.7
 Il1b
interleukin 1 beta
chr1_+_60409612 0.740 ENSMUST00000052332.8
 Abi2
abl-interactor 2
chr7_-_3720382 0.720 ENSMUST00000078451.6
 Pirb
paired Ig-like receptor B
chr5_+_100196611 0.642 ENSMUST00000066813.1
 Gm9932
predicted gene 9932
chr7_+_5080214 0.585 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
 Epn1



epsin 1



chr13_-_74482943 0.580 ENSMUST00000074369.6
 Zfp825
zinc finger protein 825
chr5_-_31108218 0.578 ENSMUST00000182776.1
ENSMUST00000182444.1
 Slc30a3

solute carrier family 30 (zinc transporter), member 3

chr8_-_84104773 0.573 ENSMUST00000041367.7
 Dcaf15
DDB1 and CUL4 associated factor 15
chr9_-_97111117 0.562 ENSMUST00000085206.4
 Slc25a36
solute carrier family 25, member 36
chr10_+_115384951 0.541 ENSMUST00000036044.8
 Zfc3h1
zinc finger, C3H1-type containing
chr10_+_79669410 0.529 ENSMUST00000020552.5
 Tpgs1
tubulin polyglutamylase complex subunit 1
chr5_-_120777628 0.498 ENSMUST00000044833.8
 Oas3
2'-5' oligoadenylate synthetase 3
chr10_+_75212065 0.446 ENSMUST00000105421.2
 Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chr7_+_24081888 0.446 ENSMUST00000068975.3
 Zfp180
zinc finger protein 180
chr4_+_62525369 0.421 ENSMUST00000062145.1
 4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr15_+_51877742 0.408 ENSMUST00000136129.1
 Utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr19_-_40588374 0.385 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
 Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chrY_-_6681243 0.378 ENSMUST00000115940.1
 Gm21719
predicted gene, 21719
chr14_-_18893376 0.364 ENSMUST00000151926.1
 Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr6_+_3993776 0.359 ENSMUST00000031673.5
 Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr13_-_8870967 0.357 ENSMUST00000164183.2
 Wdr37
WD repeat domain 37
chr12_-_54695813 0.353 ENSMUST00000110713.3
 Eapp
E2F-associated phosphoprotein
chr7_+_48789003 0.348 ENSMUST00000118927.1
ENSMUST00000125280.1
 Zdhhc13

zinc finger, DHHC domain containing 13

chr12_-_54695885 0.348 ENSMUST00000067272.8
 Eapp
E2F-associated phosphoprotein
chr16_-_62786742 0.250 ENSMUST00000152553.1
ENSMUST00000063089.5
 Nsun3

NOL1/NOP2/Sun domain family member 3

chr1_+_190928822 0.242 ENSMUST00000135364.1
 Angel2
angel homolog 2 (Drosophila)
chr14_+_79397772 0.200 ENSMUST00000022600.2
 Mtrf1
mitochondrial translational release factor 1
chr12_-_54695829 0.188 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
 Eapp



E2F-associated phosphoprotein



chr7_-_30880263 0.146 ENSMUST00000108125.2
 Cd22
CD22 antigen
chr11_-_21572193 0.095 ENSMUST00000102874.4
 Mdh1
malate dehydrogenase 1, NAD (soluble)
chr17_+_7945653 0.069 ENSMUST00000097423.2
 Rsph3a
radial spoke 3A homolog (Chlamydomonas)
chr17_-_6948283 0.065 ENSMUST00000024572.9
 Rsph3b
radial spoke 3B homolog (Chlamydomonas)
chr6_+_123229843 0.053 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
 Clec4n


C-type lectin domain family 4, member n


chr16_-_45844303 0.036 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.4 3.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.3 4.0 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.3 1.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 0.8 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.2 1.1 GO:0070459 prolactin secretion(GO:0070459)
0.2 1.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.2 3.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.9 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.4 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.1 1.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 2.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 1.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.5 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) stress response to metal ion(GO:0097501)
0.1 0.9 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 2.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.2 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 5.6 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:0007602 phototransduction(GO:0007602)
0.0 1.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.1 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.6 GO:0006862 nucleotide transport(GO:0006862)
0.0 1.4 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0031167 rRNA methylation(GO:0031167)
0.0 1.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 1.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0070695 FHF complex(GO:0070695)
0.1 2.2 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.3 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.6 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0097440 apical dendrite(GO:0097440)
0.0 2.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 5.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.3 1.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 1.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.3 3.2 GO:0038191 neuropilin binding(GO:0038191)
0.2 1.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 3.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.1 1.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.3 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.2 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 4.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 6.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 1.2 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 5.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.4 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.9 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0015026 coreceptor activity(GO:0015026)