Motif ID: Msx2_Hoxd4
Z-value: 0.991


Transcription factors associated with Msx2_Hoxd4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Msx2 | ENSMUSG00000021469.8 | Msx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Msx2 | mm10_v2_chr13_-_53473074_53473074 | -0.22 | 6.5e-02 | Click! |
Top targets:
Showing 1 to 20 of 154 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 71 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 13.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
3.1 | 9.4 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
0.1 | 9.2 | GO:0051291 | protein heterooligomerization(GO:0051291) |
2.9 | 8.6 | GO:1904395 | regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.2 | 7.0 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
2.3 | 6.8 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.3 | 6.6 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.1 | 6.4 | GO:0050852 | T cell receptor signaling pathway(GO:0050852) |
0.1 | 6.1 | GO:1904030 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
0.2 | 5.7 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.3 | 4.4 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.1 | 4.1 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.7 | 3.6 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
0.1 | 3.5 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
0.2 | 2.9 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
0.0 | 2.8 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
0.9 | 2.7 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.4 | 2.7 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.8 | 2.5 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
0.0 | 2.4 | GO:0098780 | mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 37 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 12.8 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.1 | 8.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 7.0 | GO:0005923 | bicellular tight junction(GO:0005923) |
2.3 | 6.8 | GO:0072534 | perineuronal net(GO:0072534) |
1.4 | 5.5 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.4 | 4.4 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 3.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 3.2 | GO:0005911 | cell-cell junction(GO:0005911) |
0.3 | 2.9 | GO:0043083 | synaptic cleft(GO:0043083) |
0.0 | 2.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
0.3 | 2.7 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.3 | 2.5 | GO:0044327 | dendritic spine head(GO:0044327) |
0.0 | 2.5 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 1.8 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.1 | 1.7 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 1.3 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 1.2 | GO:0015630 | microtubule cytoskeleton(GO:0015630) |
0.0 | 1.1 | GO:0016605 | PML body(GO:0016605) |
0.0 | 1.0 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 1.0 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 47 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 19.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 15.9 | GO:0005509 | calcium ion binding(GO:0005509) |
1.2 | 9.4 | GO:0050693 | LBD domain binding(GO:0050693) |
0.5 | 9.2 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
2.9 | 8.6 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
1.0 | 7.3 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 7.0 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.5 | 6.8 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.1 | 4.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 4.1 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.3 | 3.6 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.0 | 3.1 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
0.3 | 2.9 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.2 | 2.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.9 | 2.7 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.1 | 2.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 2.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 2.3 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
0.4 | 2.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.1 | 2.1 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |