Motif ID: Msx3

Z-value: 0.435


Transcription factors associated with Msx3:

Gene SymbolEntrez IDGene Name
Msx3 ENSMUSG00000025469.9 Msx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Msx3mm10_v2_chr7_-_140049140_1400491800.244.3e-02Click!


Activity profile for motif Msx3.

activity profile for motif Msx3


Sorted Z-values histogram for motif Msx3

Sorted Z-values for motif Msx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Msx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 65 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_53975246 6.228 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chrX_-_143933204 4.174 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chrX_-_143933089 3.721 ENSMUST00000087313.3
Dcx
doublecortin
chr2_-_45117349 3.510 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr1_-_158356258 3.098 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr5_+_14514918 2.838 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr4_-_14621805 2.578 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr10_+_81257277 2.508 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
Matk


megakaryocyte-associated tyrosine kinase


chr15_+_82252397 2.474 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr13_+_83732438 2.377 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr2_+_125136692 2.371 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr10_+_39612934 2.359 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr5_+_88583527 2.255 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr15_+_44787746 2.197 ENSMUST00000181839.1
2310069G16Rik
RIKEN cDNA 2310069G16 gene
chr1_-_52190901 2.083 ENSMUST00000156887.1
ENSMUST00000129107.1
Gls

glutaminase

chr2_-_33087169 1.974 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr18_+_37819543 1.879 ENSMUST00000055935.5
Pcdhga9
protocadherin gamma subfamily A, 9
chr9_-_15301555 1.865 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr7_-_127895578 1.853 ENSMUST00000033074.6
Vkorc1
vitamin K epoxide reductase complex, subunit 1
chr11_+_70018421 1.785 ENSMUST00000108588.1
Dlg4
discs, large homolog 4 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 6.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.7 4.8 GO:0019532 oxalate transport(GO:0019532)
0.6 3.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 3.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.5 2.8 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.8 2.5 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 2.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 2.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.4 2.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.6 1.9 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.8 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 1.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.4 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 1.3 GO:0019228 neuronal action potential(GO:0019228)
0.0 1.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.2 GO:0007608 sensory perception of smell(GO:0007608)
0.4 1.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) phosphate ion transmembrane transport(GO:0035435)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.7 GO:0030425 dendrite(GO:0030425)
0.0 4.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.6 2.8 GO:0044316 cone cell pedicle(GO:0044316)
0.0 2.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 2.3 GO:0071437 invadopodium(GO:0071437)
0.1 1.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.4 1.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.9 GO:0090543 Flemming body(GO:0090543)
0.0 0.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.1 GO:0005096 GTPase activator activity(GO:0005096)
0.3 7.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.4 4.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 3.5 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.8 GO:0005522 profilin binding(GO:0005522)
0.6 2.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 2.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.4 2.1 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.9 GO:0048038 quinone binding(GO:0048038)
0.0 1.9 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.2 1.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.7 GO:0043015 cAMP binding(GO:0030552) gamma-tubulin binding(GO:0043015)
0.1 1.2 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.2 1.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 0.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)