Motif ID: Mtf1

Z-value: 1.320


Transcription factors associated with Mtf1:

Gene SymbolEntrez IDGene Name
Mtf1 ENSMUSG00000028890.7 Mtf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mtf1mm10_v2_chr4_+_124802543_1248026780.344.5e-03Click!


Activity profile for motif Mtf1.

activity profile for motif Mtf1


Sorted Z-values histogram for motif Mtf1

Sorted Z-values for motif Mtf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mtf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_94172618 80.991 ENSMUST00000034214.6
 Mt2
metallothionein 2
chr8_+_94179089 51.902 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr11_-_32222233 23.224 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr11_+_63133068 16.367 ENSMUST00000108700.1
 Pmp22
peripheral myelin protein 22
chr11_+_63132569 15.244 ENSMUST00000108701.1
 Pmp22
peripheral myelin protein 22
chr1_+_135729147 14.685 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr17_+_85620816 9.919 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr1_-_169531343 8.595 ENSMUST00000028000.7
 Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr14_-_26170283 8.121 ENSMUST00000100809.4
 Plac9b
placenta specific 9b
chr1_-_169531447 7.740 ENSMUST00000111368.1
 Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_+_191906743 6.709 ENSMUST00000044954.6
 Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr1_+_131867224 6.693 ENSMUST00000112386.1
ENSMUST00000027693.7
 Rab7l1

RAB7, member RAS oncogene family-like 1

chr6_-_39118211 6.664 ENSMUST00000038398.6
 Parp12
poly (ADP-ribose) polymerase family, member 12
chr2_+_119112793 6.429 ENSMUST00000140939.1
ENSMUST00000028795.3
 Rad51

RAD51 homolog

chr1_+_157412352 6.017 ENSMUST00000061537.5
 2810025M15Rik
RIKEN cDNA 2810025M15 gene
chr7_+_119793987 5.507 ENSMUST00000033218.8
ENSMUST00000106520.1
 2610020H08Rik

RIKEN cDNA 2610020H08 gene

chr12_+_24572276 5.399 ENSMUST00000085553.5
 Grhl1
grainyhead-like 1 (Drosophila)
chr7_+_119794102 5.241 ENSMUST00000084644.2
 2610020H08Rik
RIKEN cDNA 2610020H08 gene
chr5_-_125341043 4.750 ENSMUST00000111390.1
ENSMUST00000086075.6
 Scarb1

scavenger receptor class B, member 1

chr1_+_167618246 4.738 ENSMUST00000111380.1
 Rxrg
retinoid X receptor gamma

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
19.0 132.9 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.8 31.6 GO:0032060 bleb assembly(GO:0032060)
0.4 23.2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.5 16.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 14.7 GO:0070527 platelet aggregation(GO:0070527)
1.7 11.8 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
3.3 9.9 GO:0097402 neuroblast migration(GO:0097402)
1.1 7.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
6.7 6.7 GO:0061687 detoxification of inorganic compound(GO:0061687)
1.6 6.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.9 5.4 GO:0002934 desmosome organization(GO:0002934)
1.6 4.7 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.1 4.7 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 4.7 GO:0048477 oogenesis(GO:0048477)
0.0 4.0 GO:0006342 chromatin silencing(GO:0006342)
0.1 2.7 GO:0019430 removal of superoxide radicals(GO:0019430)
0.3 2.6 GO:0046415 urate metabolic process(GO:0046415)
0.8 2.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 2.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.8 2.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 49.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.3 31.6 GO:0043218 compact myelin(GO:0043218)
0.1 23.2 GO:0000139 Golgi membrane(GO:0000139)
2.7 16.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 14.6 GO:0005925 focal adhesion(GO:0005925)
0.8 11.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 7.5 GO:0005667 transcription factor complex(GO:0005667)
0.1 6.7 GO:0030315 T-tubule(GO:0030315)
0.6 6.4 GO:0000800 lateral element(GO:0000800)
0.3 4.7 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.8 2.3 GO:0044194 cytolytic granule(GO:0044194)
0.3 2.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.9 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 1.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.1 GO:0030880 RNA polymerase complex(GO:0030880)
0.1 0.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 89.5 GO:0008270 zinc ion binding(GO:0008270)
1.0 54.6 GO:0005507 copper ion binding(GO:0005507)
0.3 25.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 11.8 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.5 9.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 6.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 6.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.9 6.4 GO:0000150 recombinase activity(GO:0000150)
0.1 5.4 GO:0031490 chromatin DNA binding(GO:0031490)
1.6 4.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.5 4.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 4.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 4.6 GO:0004519 endonuclease activity(GO:0004519)
0.1 2.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.5 2.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 2.4 GO:0031386 protein tag(GO:0031386)
0.4 2.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.5 2.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)