Motif ID: Myb

Z-value: 2.079


Transcription factors associated with Myb:

Gene SymbolEntrez IDGene Name
Myb ENSMUSG00000019982.8 Myb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybmm10_v2_chr10_-_21160925_211609840.841.5e-19Click!


Activity profile for motif Myb.

activity profile for motif Myb


Sorted Z-values histogram for motif Myb

Sorted Z-values for motif Myb



Network of associatons between targets according to the STRING database.



First level regulatory network of Myb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_118437331 28.170 ENSMUST00000006565.6
 Cdc20
cell division cycle 20
chr2_+_118814237 26.167 ENSMUST00000028803.7
ENSMUST00000126045.1
 Knstrn

kinetochore-localized astrin/SPAG5 binding

chr2_+_118814195 25.250 ENSMUST00000110842.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding
chr2_+_118813995 23.209 ENSMUST00000134661.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding
chr6_+_124829540 21.021 ENSMUST00000150120.1
 Cdca3
cell division cycle associated 3
chr2_-_127831817 20.923 ENSMUST00000028858.7
 Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr5_+_123749696 20.554 ENSMUST00000031366.7
 Kntc1
kinetochore associated 1
chr10_+_84838143 19.750 ENSMUST00000095388.4
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr9_+_72438534 19.068 ENSMUST00000034746.8
 Mns1
meiosis-specific nuclear structural protein 1
chr6_+_124829582 18.772 ENSMUST00000024270.7
 Cdca3
cell division cycle associated 3
chr9_+_72438519 17.965 ENSMUST00000184604.1
 Mns1
meiosis-specific nuclear structural protein 1
chr11_-_69921057 17.793 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
 Eif5a


eukaryotic translation initiation factor 5A


chr17_-_70851189 17.176 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr18_+_60925612 17.116 ENSMUST00000102888.3
ENSMUST00000025519.4
 Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr1_-_191575534 16.325 ENSMUST00000027933.5
 Dtl
denticleless homolog (Drosophila)
chr14_+_46760526 16.267 ENSMUST00000067426.4
 Cdkn3
cyclin-dependent kinase inhibitor 3
chr11_-_69920892 15.783 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
 Eif5a


eukaryotic translation initiation factor 5A


chrX_+_58030999 15.383 ENSMUST00000088631.4
ENSMUST00000088629.3
 Zic3

zinc finger protein of the cerebellum 3

chr2_-_172370506 15.267 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
 Aurka


aurora kinase A


chr19_+_36409719 15.232 ENSMUST00000062389.5
 Pcgf5
polycomb group ring finger 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.8 85.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
9.7 58.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 43.4 GO:0007067 mitotic nuclear division(GO:0007067)
2.3 37.2 GO:0022027 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
2.3 37.0 GO:0070986 left/right axis specification(GO:0070986)
7.2 28.8 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
5.5 27.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
4.0 24.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
1.5 24.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
2.0 22.2 GO:0034501 protein localization to kinetochore(GO:0034501)
1.0 20.9 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.2 20.1 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
3.9 19.7 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 19.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.7 18.9 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
1.2 18.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.6 18.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
1.0 18.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
3.5 17.7 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.7 16.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 74.6 GO:0035371 microtubule plus-end(GO:0035371)
0.5 59.5 GO:0000776 kinetochore(GO:0000776)
5.9 59.2 GO:0005642 annulate lamellae(GO:0005642)
0.1 59.2 GO:0005813 centrosome(GO:0005813)
0.6 36.6 GO:0005882 intermediate filament(GO:0005882)
1.1 29.6 GO:0034451 centriolar satellite(GO:0034451)
0.5 29.0 GO:0005871 kinesin complex(GO:0005871)
1.9 28.8 GO:0031616 spindle pole centrosome(GO:0031616)
1.1 27.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 21.3 GO:0005730 nucleolus(GO:0005730)
0.3 21.0 GO:0005814 centriole(GO:0005814)
5.2 20.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
6.9 20.6 GO:1990423 RZZ complex(GO:1990423)
0.9 18.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.6 18.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 17.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.3 16.8 GO:0005643 nuclear pore(GO:0005643)
2.3 16.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
5.1 15.3 GO:0042585 germinal vesicle(GO:0042585)
0.0 13.8 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.5 58.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 34.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.5 31.4 GO:0003777 microtubule motor activity(GO:0003777)
7.2 28.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
4.7 28.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 25.5 GO:0019904 protein domain specific binding(GO:0019904)
1.1 24.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 17.4 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.6 17.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.8 17.2 GO:0070410 co-SMAD binding(GO:0070410)
0.1 17.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.6 16.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
2.2 15.3 GO:0035174 histone serine kinase activity(GO:0035174)
1.2 14.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 13.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.5 13.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 12.6 GO:0042393 histone binding(GO:0042393)
1.0 12.2 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.3 12.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
3.0 12.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)