Motif ID: Myb
Z-value: 2.079
Transcription factors associated with Myb:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Myb | ENSMUSG00000019982.8 | Myb |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Myb | mm10_v2_chr10_-_21160925_21160984 | 0.84 | 1.5e-19 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.7 | 58.4 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 7.2 | 28.8 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 5.5 | 27.4 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 5.1 | 15.3 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 4.8 | 85.8 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 4.0 | 24.2 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 3.9 | 19.7 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 3.5 | 17.7 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 2.8 | 14.2 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 2.8 | 8.5 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 2.6 | 18.4 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 2.5 | 9.9 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 2.4 | 12.0 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 2.3 | 37.2 | GO:0022027 | interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953) |
| 2.3 | 37.0 | GO:0070986 | left/right axis specification(GO:0070986) |
| 2.0 | 22.2 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 2.0 | 6.0 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 1.9 | 11.6 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 1.9 | 13.0 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
| 1.6 | 8.1 | GO:0070460 | thyroid-stimulating hormone secretion(GO:0070460) |
| 1.5 | 4.6 | GO:1901896 | positive regulation of calcium-transporting ATPase activity(GO:1901896) |
| 1.5 | 24.2 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 1.5 | 4.5 | GO:2000564 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
| 1.5 | 11.8 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 1.4 | 7.1 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) cellular response to potassium ion starvation(GO:0051365) |
| 1.4 | 12.5 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 1.3 | 10.7 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 1.3 | 11.9 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 1.3 | 15.6 | GO:0019985 | translesion synthesis(GO:0019985) |
| 1.2 | 6.1 | GO:0019659 | lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 1.2 | 8.4 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 1.2 | 18.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 1.1 | 5.6 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
| 1.0 | 20.9 | GO:0007063 | regulation of sister chromatid cohesion(GO:0007063) |
| 1.0 | 3.1 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 1.0 | 18.4 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 1.0 | 4.8 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.9 | 5.5 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
| 0.9 | 3.7 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.8 | 0.8 | GO:0061511 | centriole elongation(GO:0061511) |
| 0.8 | 4.0 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038) |
| 0.8 | 3.2 | GO:0044340 | canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340) |
| 0.8 | 4.8 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.8 | 2.3 | GO:0014028 | notochord formation(GO:0014028) |
| 0.7 | 7.3 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.7 | 3.6 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
| 0.7 | 16.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.7 | 18.9 | GO:0034724 | DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724) |
| 0.7 | 6.8 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.7 | 2.6 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.6 | 14.5 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.6 | 0.6 | GO:1901536 | regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) |
| 0.6 | 3.7 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.6 | 2.4 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.6 | 3.5 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.6 | 3.5 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.6 | 12.2 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.6 | 8.6 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.6 | 1.7 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
| 0.6 | 16.0 | GO:0007099 | centriole replication(GO:0007099) |
| 0.5 | 1.6 | GO:0090202 | transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 0.5 | 3.1 | GO:1902965 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 0.5 | 2.6 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.5 | 2.6 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.4 | 3.6 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.4 | 1.8 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.4 | 1.8 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
| 0.4 | 2.2 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.4 | 1.3 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.4 | 6.2 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.4 | 4.5 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.4 | 7.3 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.4 | 0.8 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.4 | 4.0 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
| 0.4 | 1.6 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 0.4 | 1.2 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.4 | 4.4 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.4 | 2.5 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.3 | 5.3 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.3 | 2.0 | GO:0009169 | purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) |
| 0.3 | 1.0 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.3 | 3.8 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.3 | 1.2 | GO:1904008 | response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009) |
| 0.3 | 2.7 | GO:0002155 | regulation of thyroid hormone mediated signaling pathway(GO:0002155) |
| 0.3 | 3.8 | GO:2000780 | negative regulation of double-strand break repair(GO:2000780) |
| 0.3 | 8.4 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.3 | 3.2 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.3 | 5.3 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273) |
| 0.3 | 2.3 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.3 | 1.3 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.2 | 11.5 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.2 | 2.6 | GO:0044380 | protein localization to cytoskeleton(GO:0044380) |
| 0.2 | 2.4 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.2 | 1.5 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.2 | 5.2 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
| 0.2 | 3.5 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.2 | 3.5 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.2 | 20.1 | GO:0007093 | mitotic cell cycle checkpoint(GO:0007093) |
| 0.2 | 0.9 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.2 | 1.6 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.2 | 14.2 | GO:0048663 | neuron fate commitment(GO:0048663) |
| 0.2 | 5.6 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.2 | 9.9 | GO:0007127 | meiosis I(GO:0007127) |
| 0.1 | 0.4 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.1 | 1.3 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 3.8 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
| 0.1 | 2.2 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.1 | 19.1 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.1 | 1.0 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.1 | 0.8 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.1 | 43.4 | GO:0007067 | mitotic nuclear division(GO:0007067) |
| 0.1 | 1.4 | GO:0060049 | regulation of protein glycosylation(GO:0060049) |
| 0.1 | 1.9 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 2.4 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.1 | 2.9 | GO:0048255 | mRNA stabilization(GO:0048255) |
| 0.1 | 0.4 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 0.5 | GO:0019695 | choline metabolic process(GO:0019695) |
| 0.1 | 1.0 | GO:0030728 | ovulation(GO:0030728) |
| 0.1 | 2.7 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 0.6 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 6.2 | GO:0008584 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.1 | 1.2 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 1.0 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 3.7 | GO:0051321 | meiotic cell cycle(GO:0051321) |
| 0.1 | 6.5 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.1 | 5.1 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
| 0.1 | 3.4 | GO:0040017 | positive regulation of cell migration(GO:0030335) positive regulation of locomotion(GO:0040017) positive regulation of cell motility(GO:2000147) |
| 0.1 | 3.1 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.1 | 0.9 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 1.0 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.1 | 2.1 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.1 | 0.3 | GO:1901978 | positive regulation of cell cycle checkpoint(GO:1901978) |
| 0.1 | 6.3 | GO:0000082 | G1/S transition of mitotic cell cycle(GO:0000082) |
| 0.1 | 7.5 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.1 | 2.4 | GO:0000271 | polysaccharide biosynthetic process(GO:0000271) |
| 0.0 | 2.6 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
| 0.0 | 2.4 | GO:0002209 | behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) |
| 0.0 | 4.6 | GO:0030218 | erythrocyte differentiation(GO:0030218) |
| 0.0 | 0.2 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
| 0.0 | 7.0 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 2.5 | GO:0070373 | negative regulation of ERK1 and ERK2 cascade(GO:0070373) |
| 0.0 | 0.8 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
| 0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.0 | 0.4 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.0 | 1.1 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.9 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.0 | 1.5 | GO:0016568 | chromatin modification(GO:0016568) |
| 0.0 | 0.1 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.0 | 0.2 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 0.0 | 0.6 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 0.8 | GO:0007548 | sex differentiation(GO:0007548) |
| 0.0 | 0.7 | GO:0009060 | aerobic respiration(GO:0009060) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.9 | 20.6 | GO:1990423 | RZZ complex(GO:1990423) |
| 5.9 | 59.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 5.2 | 20.9 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 5.1 | 15.3 | GO:0042585 | germinal vesicle(GO:0042585) |
| 2.8 | 8.5 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 2.4 | 7.3 | GO:1990047 | spindle matrix(GO:1990047) |
| 2.3 | 16.3 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 2.3 | 74.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 1.9 | 28.8 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 1.5 | 10.7 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 1.5 | 10.6 | GO:0001940 | male pronucleus(GO:0001940) |
| 1.3 | 5.2 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
| 1.3 | 9.0 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 1.1 | 29.6 | GO:0034451 | centriolar satellite(GO:0034451) |
| 1.1 | 3.2 | GO:0036128 | CatSper complex(GO:0036128) |
| 1.1 | 27.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 1.0 | 7.3 | GO:0001740 | Barr body(GO:0001740) |
| 1.0 | 4.8 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
| 0.9 | 18.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.9 | 2.6 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 0.8 | 4.8 | GO:0000796 | condensin complex(GO:0000796) |
| 0.7 | 3.5 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.7 | 4.7 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.7 | 5.9 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.6 | 36.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.6 | 10.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.6 | 18.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.5 | 1.6 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.5 | 2.6 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.5 | 29.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.5 | 6.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.5 | 4.5 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.5 | 7.3 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.5 | 3.8 | GO:0098536 | deuterosome(GO:0098536) |
| 0.5 | 59.5 | GO:0000776 | kinetochore(GO:0000776) |
| 0.5 | 2.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.4 | 6.1 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.4 | 1.1 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.4 | 2.6 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.3 | 1.7 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.3 | 1.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.3 | 11.2 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.3 | 0.9 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.3 | 16.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.3 | 13.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.3 | 3.1 | GO:0051286 | cell tip(GO:0051286) |
| 0.3 | 21.0 | GO:0005814 | centriole(GO:0005814) |
| 0.3 | 5.6 | GO:0005605 | basal lamina(GO:0005605) |
| 0.2 | 1.4 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.2 | 13.7 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.2 | 2.0 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.2 | 3.5 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.2 | 0.6 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.2 | 17.3 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.2 | 12.7 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.2 | 2.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.2 | 1.2 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 59.2 | GO:0005813 | centrosome(GO:0005813) |
| 0.1 | 2.4 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 1.8 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.1 | 3.8 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 3.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 10.0 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 9.6 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 0.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.1 | 2.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 2.3 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 1.0 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 3.1 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 8.0 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 8.1 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.1 | 1.2 | GO:0008287 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
| 0.1 | 13.0 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.1 | 0.3 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 9.4 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 1.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 3.4 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.5 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 13.8 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 1.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 21.3 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 1.9 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.6 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 4.2 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.0 | 2.3 | GO:0031968 | mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968) |
| 0.0 | 3.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.9 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 1.1 | GO:1990204 | oxidoreductase complex(GO:1990204) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.2 | 28.8 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 4.7 | 28.2 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 4.5 | 58.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 3.6 | 10.7 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
| 3.5 | 10.6 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 3.0 | 12.1 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 2.2 | 15.3 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 1.7 | 10.1 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 1.6 | 9.4 | GO:0008494 | translation activator activity(GO:0008494) |
| 1.5 | 6.1 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 1.2 | 9.9 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 1.2 | 14.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 1.1 | 10.6 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 1.1 | 24.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 1.0 | 12.2 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
| 0.9 | 3.7 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.8 | 17.2 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.8 | 2.3 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.8 | 3.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.7 | 6.5 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.7 | 5.6 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.6 | 2.6 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.6 | 0.6 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
| 0.6 | 12.1 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.6 | 17.3 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.6 | 6.2 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.6 | 16.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.5 | 13.0 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.5 | 31.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.5 | 4.8 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.5 | 6.0 | GO:0048038 | quinone binding(GO:0048038) |
| 0.5 | 2.7 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.4 | 1.3 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 0.4 | 5.2 | GO:0031386 | protein tag(GO:0031386) |
| 0.4 | 6.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.4 | 7.1 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.3 | 3.5 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.3 | 4.8 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.3 | 1.7 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.3 | 4.0 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.3 | 5.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.3 | 2.8 | GO:0032564 | dATP binding(GO:0032564) |
| 0.3 | 4.8 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.3 | 1.4 | GO:0043842 | Kdo transferase activity(GO:0043842) |
| 0.3 | 1.6 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.3 | 4.6 | GO:0051861 | glycolipid binding(GO:0051861) |
| 0.3 | 12.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.3 | 8.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.3 | 1.5 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.2 | 17.4 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.2 | 2.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.2 | 2.2 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.2 | 1.0 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
| 0.2 | 2.6 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.2 | 3.2 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.2 | 4.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.2 | 7.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 2.8 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.2 | 1.2 | GO:0043426 | MRF binding(GO:0043426) |
| 0.2 | 13.2 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.2 | 1.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.2 | 7.5 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.2 | 10.4 | GO:0000987 | core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159) |
| 0.2 | 3.8 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.2 | 5.9 | GO:0070888 | E-box binding(GO:0070888) |
| 0.2 | 4.9 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.2 | 6.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 4.0 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 6.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 2.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.5 | GO:0004104 | choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.1 | 34.6 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 4.7 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 3.5 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 17.1 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.1 | 7.0 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.1 | 1.3 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.1 | 3.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 1.6 | GO:0015149 | hexose transmembrane transporter activity(GO:0015149) |
| 0.1 | 3.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 7.4 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.1 | 2.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 0.5 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 1.8 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 0.8 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 1.0 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.1 | 1.7 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.1 | 12.6 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 4.3 | GO:0003774 | motor activity(GO:0003774) |
| 0.1 | 1.5 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 1.0 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.1 | 1.3 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 1.0 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 3.9 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 1.2 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 1.1 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 1.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.0 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 3.8 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.0 | 4.4 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 25.5 | GO:0019904 | protein domain specific binding(GO:0019904) |
| 0.0 | 1.0 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 3.8 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
| 0.0 | 0.8 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.9 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 1.5 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 1.0 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.5 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 1.1 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
| 0.0 | 0.0 | GO:0030619 | U1 snRNA binding(GO:0030619) |
| 0.0 | 0.6 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.4 | GO:0005484 | SNAP receptor activity(GO:0005484) |
