Motif ID: Mzf1

Z-value: 0.887


Transcription factors associated with Mzf1:

Gene SymbolEntrez IDGene Name
Mzf1 ENSMUSG00000030380.10 Mzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mzf1mm10_v2_chr7_-_13054665_130547640.181.4e-01Click!


Activity profile for motif Mzf1.

activity profile for motif Mzf1


Sorted Z-values histogram for motif Mzf1

Sorted Z-values for motif Mzf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mzf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_109010955 6.552 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr12_+_105336922 5.884 ENSMUST00000180503.1
 2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr4_+_104367549 5.691 ENSMUST00000106830.2
 Dab1
disabled 1
chr11_+_70018421 5.280 ENSMUST00000108588.1
 Dlg4
discs, large homolog 4 (Drosophila)
chr3_+_96596628 4.982 ENSMUST00000058943.7
 Ankrd34a
ankyrin repeat domain 34A
chr1_-_154725920 4.879 ENSMUST00000004214.8
 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr1_+_167001457 4.813 ENSMUST00000126198.1
 Fam78b
family with sequence similarity 78, member B
chr6_-_13838432 4.617 ENSMUST00000115492.1
 Gpr85
G protein-coupled receptor 85
chr11_+_70018728 4.614 ENSMUST00000018700.6
ENSMUST00000134376.2
 Dlg4

discs, large homolog 4 (Drosophila)

chr10_+_13966268 4.522 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr17_+_28142267 4.469 ENSMUST00000043503.3
 Scube3
signal peptide, CUB domain, EGF-like 3
chrX_-_143933089 4.279 ENSMUST00000087313.3
 Dcx
doublecortin
chr14_-_39472825 4.227 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
 Nrg3


neuregulin 3


chr1_+_167001417 4.200 ENSMUST00000165874.1
 Fam78b
family with sequence similarity 78, member B
chr11_-_95514570 4.120 ENSMUST00000058866.7
 Nxph3
neurexophilin 3
chr11_+_105589970 4.084 ENSMUST00000168598.1
ENSMUST00000100330.3
 Tanc2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr1_-_56971762 4.035 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr6_-_85502858 3.674 ENSMUST00000161546.1
ENSMUST00000161078.1
 Fbxo41

F-box protein 41

chr4_-_20778527 3.655 ENSMUST00000119374.1
 Nkain3
Na+/K+ transporting ATPase interacting 3
chr1_+_66321708 3.645 ENSMUST00000114013.1
 Map2
microtubule-associated protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 312 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 18.9 GO:2000821 regulation of grooming behavior(GO:2000821)
0.2 9.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 9.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 9.6 GO:0035418 protein localization to synapse(GO:0035418)
0.4 8.7 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.4 7.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.5 7.0 GO:0071625 vocalization behavior(GO:0071625)
0.8 6.6 GO:0005513 detection of calcium ion(GO:0005513)
1.3 6.4 GO:0007256 activation of JNKK activity(GO:0007256)
2.1 6.3 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
1.9 5.7 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.6 5.3 GO:0071420 cellular response to histamine(GO:0071420)
0.7 5.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.6 5.0 GO:0045161 neuronal ion channel clustering(GO:0045161)
1.6 4.7 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
1.6 4.7 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.7 4.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.6 4.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.5 4.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 4.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 37.4 GO:0060076 excitatory synapse(GO:0060076)
1.1 21.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.4 18.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 15.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 12.6 GO:0043198 dendritic shaft(GO:0043198)
0.4 9.7 GO:0071565 nBAF complex(GO:0071565)
0.1 7.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 6.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.3 6.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 6.0 GO:0070382 exocytic vesicle(GO:0070382)
0.1 5.8 GO:0055037 recycling endosome(GO:0055037)
0.1 5.6 GO:0042734 presynaptic membrane(GO:0042734)
0.1 5.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 5.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 5.1 GO:0031045 dense core granule(GO:0031045)
0.9 4.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 4.4 GO:0045202 synapse(GO:0045202)
1.1 4.3 GO:0090537 CERF complex(GO:0090537)
0.1 4.3 GO:0005657 replication fork(GO:0005657)
0.0 4.2 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 206 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 19.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
2.1 16.9 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
1.0 13.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 9.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.4 9.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 8.7 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.3 7.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 7.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 6.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 6.9 GO:0005096 GTPase activator activity(GO:0005096)
0.5 6.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 6.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 6.4 GO:0045499 chemorepellent activity(GO:0045499)
0.2 5.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 5.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 5.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
1.6 4.7 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.8 4.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 4.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 4.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)