Motif ID: Neurod1

Z-value: 1.383


Transcription factors associated with Neurod1:

Gene SymbolEntrez IDGene Name
Neurod1 ENSMUSG00000034701.9 Neurod1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurod1mm10_v2_chr2_-_79456750_794567610.781.1e-15Click!


Activity profile for motif Neurod1.

activity profile for motif Neurod1


Sorted Z-values histogram for motif Neurod1

Sorted Z-values for motif Neurod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 36.400 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr11_-_98329641 27.890 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr12_+_29528382 19.371 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr10_+_69706326 18.152 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr5_-_142608785 16.595 ENSMUST00000037048.7
Mmd2
monocyte to macrophage differentiation-associated 2
chr2_-_29253001 16.099 ENSMUST00000071201.4
Ntng2
netrin G2
chr11_+_32000452 15.028 ENSMUST00000020537.2
ENSMUST00000109409.1
Nsg2

neuron specific gene family member 2

chr3_+_18054258 14.823 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr16_+_42907563 14.816 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr2_-_25319095 14.414 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr6_+_54681687 13.853 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr18_+_45268876 13.746 ENSMUST00000183850.1
ENSMUST00000066890.7
Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr15_-_99705490 13.633 ENSMUST00000163472.2
Gm17349
predicted gene, 17349
chr6_-_136171722 13.126 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_+_90885860 12.629 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr10_-_109010955 12.345 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr11_+_32000496 11.862 ENSMUST00000093219.3
Nsg2
neuron specific gene family member 2
chr3_-_84259812 11.734 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr1_+_9601163 10.944 ENSMUST00000088666.3
3110035E14Rik
RIKEN cDNA 3110035E14 gene
chr4_-_20778527 10.942 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 134 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 42.8 GO:0021542 dentate gyrus development(GO:0021542)
0.2 29.9 GO:0050808 synapse organization(GO:0050808)
9.3 27.9 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.2 26.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 21.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.2 19.8 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
1.7 18.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.8 16.6 GO:0019835 cytolysis(GO:0019835)
5.5 16.5 GO:1900673 olefin metabolic process(GO:1900673)
0.2 16.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
2.5 14.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.4 14.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 13.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.4 13.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.8 13.4 GO:2000821 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
1.5 12.3 GO:0005513 detection of calcium ion(GO:0005513)
0.1 11.4 GO:1900006 positive regulation of dendrite development(GO:1900006)
1.0 10.3 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
1.3 10.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.5 10.0 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 30.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 26.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.1 22.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.0 20.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.6 19.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.4 16.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
4.1 16.5 GO:0044307 dendritic branch(GO:0044307)
0.5 15.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 13.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.5 13.1 GO:0043083 synaptic cleft(GO:0043083)
0.8 12.3 GO:0031045 dense core granule(GO:0031045)
0.2 11.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.8 10.3 GO:0042788 polysomal ribosome(GO:0042788)
0.3 9.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.7 8.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 7.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.4 7.2 GO:0000421 autophagosome membrane(GO:0000421)
1.0 7.0 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 6.2 GO:0060170 ciliary membrane(GO:0060170)
0.1 6.0 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 32.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
4.5 26.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 26.0 GO:0070888 E-box binding(GO:0070888)
0.0 25.3 GO:0004672 protein kinase activity(GO:0004672)
0.8 25.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 19.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
1.3 19.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 19.2 GO:0017022 myosin binding(GO:0017022)
0.1 17.9 GO:0042393 histone binding(GO:0042393)
0.1 14.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
3.4 13.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.7 13.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.9 12.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 12.8 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.5 12.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
1.0 11.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.3 11.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 10.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
2.0 10.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 9.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)