Motif ID: Neurog2

Z-value: 0.480


Transcription factors associated with Neurog2:

Gene SymbolEntrez IDGene Name
Neurog2 ENSMUSG00000027967.7 Neurog2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurog2mm10_v2_chr3_+_127633134_127633140-0.253.7e-02Click!


Activity profile for motif Neurog2.

activity profile for motif Neurog2


Sorted Z-values histogram for motif Neurog2

Sorted Z-values for motif Neurog2



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurog2

PNG image of the network

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Top targets:


Showing 1 to 20 of 173 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_141598206 3.802 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr11_-_102365111 3.442 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr7_-_126704816 3.009 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr7_-_126704736 2.840 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr10_+_69706326 2.531 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr7_-_126704522 2.522 ENSMUST00000135087.1
Coro1a
coronin, actin binding protein 1A
chr3_-_120886691 2.346 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr7_+_30314810 2.342 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
Syne4



spectrin repeat containing, nuclear envelope family member 4



chr13_+_16014457 2.174 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr3_+_118430299 2.106 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr11_-_75796048 2.063 ENSMUST00000021209.7
Doc2b
double C2, beta
chr10_+_110920170 1.590 ENSMUST00000020403.5
Csrp2
cysteine and glycine-rich protein 2
chr10_+_69534039 1.511 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr9_-_21918089 1.458 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
Rab3d



RAB3D, member RAS oncogene family



chr8_-_106337987 1.427 ENSMUST00000067512.7
Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr3_+_18054258 1.355 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr5_-_66618636 1.353 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr15_-_76918010 1.345 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chr19_+_20601958 1.344 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr11_+_73160403 1.281 ENSMUST00000006104.3
P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 8.4 GO:0032796 uropod organization(GO:0032796)
0.4 4.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 3.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 3.4 GO:0046685 response to activity(GO:0014823) response to arsenic-containing substance(GO:0046685)
0.0 2.5 GO:0030048 actin filament-based movement(GO:0030048)
0.3 2.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.4 2.2 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 2.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.5 1.9 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.3 1.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 1.5 GO:0007405 neuroblast proliferation(GO:0007405)
0.2 1.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 1.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.4 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069)
0.4 1.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.3 1.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 1.3 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 1.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.4 GO:0001891 phagocytic cup(GO:0001891)
0.2 4.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 3.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 3.6 GO:0044453 nuclear membrane part(GO:0044453)
0.1 3.4 GO:0014704 intercalated disc(GO:0014704)
0.7 2.2 GO:0043512 inhibin A complex(GO:0043512)
0.0 2.1 GO:0031201 SNARE complex(GO:0031201)
0.1 1.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 1.5 GO:0042588 zymogen granule(GO:0042588)
0.1 1.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.1 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.8 GO:0070938 contractile ring(GO:0070938)
0.1 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 8.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 4.1 GO:0031005 filamin binding(GO:0031005)
0.1 4.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 3.4 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 2.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.4 2.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.6 1.9 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 1.5 GO:0031489 myosin V binding(GO:0031489)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.3 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 1.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.2 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)