Motif ID: Nfat5

Z-value: 0.717


Transcription factors associated with Nfat5:

Gene SymbolEntrez IDGene Name
Nfat5 ENSMUSG00000003847.10 Nfat5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfat5mm10_v2_chr8_+_107293463_1072934830.399.1e-04Click!


Activity profile for motif Nfat5.

activity profile for motif Nfat5


Sorted Z-values histogram for motif Nfat5

Sorted Z-values for motif Nfat5



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfat5

PNG image of the network

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Top targets:


Showing 1 to 20 of 92 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_97417730 5.723 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr6_-_101377897 4.876 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr6_+_120773633 4.539 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr6_-_58907120 4.290 ENSMUST00000059539.3
 Nap1l5
nucleosome assembly protein 1-like 5
chr4_-_82505749 4.207 ENSMUST00000107245.2
ENSMUST00000107246.1
 Nfib

nuclear factor I/B

chr4_-_82505707 4.197 ENSMUST00000107248.1
ENSMUST00000107247.1
 Nfib

nuclear factor I/B

chr5_-_104021919 3.527 ENSMUST00000031251.9
 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr7_+_99535652 3.503 ENSMUST00000032995.8
ENSMUST00000162404.1
 Arrb1

arrestin, beta 1

chr1_+_24678536 3.388 ENSMUST00000095062.3
 Lmbrd1
LMBR1 domain containing 1
chr5_+_139423151 3.239 ENSMUST00000066211.4
 Gper1
G protein-coupled estrogen receptor 1
chr2_+_68117713 3.237 ENSMUST00000112346.2
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr9_-_29963112 3.191 ENSMUST00000075069.4
 Ntm
neurotrimin
chr7_+_99535439 3.142 ENSMUST00000098266.2
ENSMUST00000179755.1
 Arrb1

arrestin, beta 1

chr14_-_101609033 3.074 ENSMUST00000161991.1
ENSMUST00000100340.3
 Tbc1d4

TBC1 domain family, member 4

chr5_-_104021799 2.969 ENSMUST00000119025.1
 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr9_+_92457369 2.928 ENSMUST00000034941.7
 Plscr4
phospholipid scramblase 4
chr10_-_78352212 2.422 ENSMUST00000146899.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr4_-_138396438 2.367 ENSMUST00000105032.2
 Fam43b
family with sequence similarity 43, member B
chr10_+_21994666 2.202 ENSMUST00000020145.5
 Sgk1
serum/glucocorticoid regulated kinase 1
chr10_-_95415484 2.201 ENSMUST00000172070.1
ENSMUST00000150432.1
 Socs2

suppressor of cytokine signaling 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
2.1 8.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.9 6.6 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.6 6.5 GO:0042447 hormone catabolic process(GO:0042447)
0.2 5.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 4.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.3 4.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 4.3 GO:0006334 nucleosome assembly(GO:0006334)
0.4 3.4 GO:0032264 IMP salvage(GO:0032264)
0.2 3.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
1.1 3.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.1 3.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.2 3.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 3.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 2.5 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 2.2 GO:0030575 nuclear body organization(GO:0030575)
0.1 2.1 GO:0046325 negative regulation of glucose import(GO:0046325)
0.5 2.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.3 2.0 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 2.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 8.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 6.9 GO:0005811 lipid particle(GO:0005811)
0.4 6.6 GO:0031143 pseudopodium(GO:0031143)
0.1 4.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 3.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 3.2 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.7 GO:0000139 Golgi membrane(GO:0000139)
0.3 2.2 GO:0042382 paraspeckles(GO:0042382)
0.3 2.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.2 1.2 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.0 GO:0042629 mast cell granule(GO:0042629)
0.1 1.0 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.0 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.8 GO:0072562 blood microparticle(GO:0072562)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 8.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 8.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
2.2 6.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.9 6.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 4.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.6 GO:0015293 symporter activity(GO:0015293)
0.5 4.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.7 3.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 3.4 GO:0031419 cobalamin binding(GO:0031419)
0.5 3.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.1 3.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.4 3.2 GO:1990239 steroid hormone binding(GO:1990239)
0.4 3.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 3.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.4 2.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.7 2.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 2.0 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.4 1.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 1.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 1.4 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)