Motif ID: Nfe2l1_Mafg

Z-value: 1.042

Transcription factors associated with Nfe2l1_Mafg:

Gene SymbolEntrez IDGene Name
Mafg ENSMUSG00000051510.7 Mafg
Mafg ENSMUSG00000053906.4 Mafg
Nfe2l1 ENSMUSG00000038615.11 Nfe2l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafgmm10_v2_chr11_-_120633594_120633605-0.694.3e-11Click!
Nfe2l1mm10_v2_chr11_-_96829483_968295020.217.9e-02Click!


Activity profile for motif Nfe2l1_Mafg.

activity profile for motif Nfe2l1_Mafg


Sorted Z-values histogram for motif Nfe2l1_Mafg

Sorted Z-values for motif Nfe2l1_Mafg



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 45.401 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_-_137314394 10.242 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr17_+_78491549 9.661 ENSMUST00000079363.4
 Gm10093
predicted pseudogene 10093
chr12_-_10900296 8.033 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chrX_-_141874870 7.335 ENSMUST00000182079.1
 Gm15294
predicted gene 15294
chr9_-_79977782 6.833 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr12_-_54986363 6.818 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr3_+_85915722 6.691 ENSMUST00000054148.7
 Gm9790
predicted gene 9790
chr4_-_63662910 6.603 ENSMUST00000184252.1
 Gm11214
predicted gene 11214
chr1_-_65051119 5.627 ENSMUST00000161960.1
ENSMUST00000087359.5
 Cryge

crystallin, gamma E

chr11_-_33276334 5.592 ENSMUST00000183831.1
 Gm12117
predicted gene 12117
chr12_-_56535047 5.580 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr14_-_76237353 5.321 ENSMUST00000095471.4
 Rps2-ps6
ribosomal protein S2, pseudogene 6
chr7_-_116038734 4.986 ENSMUST00000166877.1
 Sox6
SRY-box containing gene 6
chr17_+_43952999 4.848 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr2_+_130277157 4.794 ENSMUST00000028890.8
ENSMUST00000159373.1
 Nop56

NOP56 ribonucleoprotein

chr1_-_45890078 4.735 ENSMUST00000183590.1
 Gm5269
predicted gene 5269
chr5_+_128601106 3.986 ENSMUST00000117102.2
 Fzd10
frizzled homolog 10 (Drosophila)
chr6_-_99044414 3.868 ENSMUST00000177507.1
ENSMUST00000123992.1
 Foxp1

forkhead box P1

chr5_+_30913398 3.865 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.6 45.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 6.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 6.2 GO:0000077 DNA damage checkpoint(GO:0000077)
1.9 5.6 GO:0021759 globus pallidus development(GO:0021759)
0.5 5.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 4.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 4.8 GO:0000154 rRNA modification(GO:0000154)
0.1 4.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 4.4 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.6 4.3 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.5 4.0 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.5 3.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 3.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
1.2 3.7 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
0.6 3.5 GO:0060242 contact inhibition(GO:0060242)
0.3 3.4 GO:0060539 diaphragm development(GO:0060539)
0.3 3.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 3.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.4 3.2 GO:0060594 mammary gland specification(GO:0060594)
0.0 3.2 GO:0007519 skeletal muscle tissue development(GO:0007519)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.1 GO:0005667 transcription factor complex(GO:0005667)
1.4 6.8 GO:0008623 CHRAC(GO:0008623)
0.1 5.6 GO:1990391 DNA repair complex(GO:1990391)
0.6 4.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 4.4 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 4.1 GO:0005581 collagen trimer(GO:0005581)
0.3 3.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 3.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 2.8 GO:0005811 lipid particle(GO:0005811)
0.0 2.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 2.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.6 2.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 2.4 GO:0000502 proteasome complex(GO:0000502)
0.1 2.2 GO:0016460 myosin II complex(GO:0016460)
0.0 2.2 GO:0031985 Golgi cisterna(GO:0031985)
0.4 2.1 GO:0071817 MMXD complex(GO:0071817)
0.3 2.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 2.1 GO:0070852 cell body fiber(GO:0070852)
0.1 2.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 50.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 17.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 6.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 6.2 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.6 5.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 5.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.3 5.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 5.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.4 5.4 GO:0015197 peptide transporter activity(GO:0015197)
0.8 4.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 4.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 4.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 3.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
1.1 3.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.7 3.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 3.1 GO:0019905 syntaxin binding(GO:0019905)
0.3 3.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 2.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)