Motif ID: Nfe2l2

Z-value: 0.578


Transcription factors associated with Nfe2l2:

Gene SymbolEntrez IDGene Name
Nfe2l2 ENSMUSG00000015839.6 Nfe2l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfe2l2mm10_v2_chr2_-_75704535_757046410.541.2e-06Click!


Activity profile for motif Nfe2l2.

activity profile for motif Nfe2l2


Sorted Z-values histogram for motif Nfe2l2

Sorted Z-values for motif Nfe2l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_126799163 8.493 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr7_-_126799134 8.142 ENSMUST00000087566.4
Aldoa
aldolase A, fructose-bisphosphate
chr17_+_86963279 7.524 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chrX_+_164269371 5.848 ENSMUST00000145412.1
ENSMUST00000033749.7
Pir

pirin

chr5_+_128601106 5.426 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chr4_+_116685859 5.128 ENSMUST00000129315.1
ENSMUST00000106470.1
Prdx1

peroxiredoxin 1

chr4_+_116685544 4.612 ENSMUST00000135573.1
ENSMUST00000151129.1
Prdx1

peroxiredoxin 1

chrX_-_52613913 4.541 ENSMUST00000069360.7
Gpc3
glypican 3
chrX_-_52613936 4.225 ENSMUST00000114857.1
Gpc3
glypican 3
chr2_+_153649442 4.075 ENSMUST00000072997.3
ENSMUST00000109773.1
ENSMUST00000109774.2
ENSMUST00000081628.6
ENSMUST00000103151.1
ENSMUST00000088976.5
ENSMUST00000109772.1
ENSMUST00000103150.3
ENSMUST00000056495.7
Dnmt3b








DNA methyltransferase 3B








chr18_-_53418004 3.970 ENSMUST00000025419.7
Ppic
peptidylprolyl isomerase C
chr18_+_61045139 3.775 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr7_-_44997535 3.760 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chr1_+_165769392 3.733 ENSMUST00000040298.4
Creg1
cellular repressor of E1A-stimulated genes 1
chr3_+_137623672 3.692 ENSMUST00000053855.7
Ddit4l
DNA-damage-inducible transcript 4-like
chr3_+_131110350 3.514 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr11_-_109473598 3.439 ENSMUST00000070152.5
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr10_+_17796256 3.433 ENSMUST00000037964.6
Txlnb
taxilin beta
chr7_-_44997221 3.351 ENSMUST00000152341.1
Bcl2l12
BCL2-like 12 (proline rich)
chr16_-_18811972 3.262 ENSMUST00000000028.7
ENSMUST00000115585.1
Cdc45

cell division cycle 45

chr10_-_34418465 3.200 ENSMUST00000099973.3
ENSMUST00000105512.1
ENSMUST00000047885.7
Nt5dc1


5'-nucleotidase domain containing 1


chr12_+_80518990 3.173 ENSMUST00000021558.6
Galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr14_+_62292475 2.923 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr18_+_61639542 2.775 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr1_-_172219715 2.627 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr8_+_106510853 2.602 ENSMUST00000080797.6
Cdh3
cadherin 3
chr17_-_47834682 2.581 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr3_-_141982224 2.530 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr17_-_25570678 2.473 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr7_-_102250086 2.468 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr11_-_30649510 2.240 ENSMUST00000074613.3
Acyp2
acylphosphatase 2, muscle type
chr2_+_180171485 2.215 ENSMUST00000061437.4
Adrm1
adhesion regulating molecule 1
chr1_+_136018062 2.197 ENSMUST00000117950.1
Tmem9
transmembrane protein 9
chr1_+_136017967 2.170 ENSMUST00000063719.8
ENSMUST00000118832.1
Tmem9

transmembrane protein 9

chr3_+_28805436 2.126 ENSMUST00000043867.5
Rpl22l1
ribosomal protein L22 like 1
chr11_+_78178105 2.024 ENSMUST00000147819.1
Tlcd1
TLC domain containing 1
chr5_-_100500592 1.996 ENSMUST00000149714.1
ENSMUST00000046154.5
Lin54

lin-54 homolog (C. elegans)

chr17_-_70998010 1.944 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr13_+_113342548 1.876 ENSMUST00000078163.7
BC067074
cDNA sequence BC067074
chr2_+_25395866 1.853 ENSMUST00000028328.2
Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr4_-_57956283 1.771 ENSMUST00000030051.5
Txn1
thioredoxin 1
chr2_-_130397525 1.750 ENSMUST00000028897.7
Cpxm1
carboxypeptidase X 1 (M14 family)
chr3_+_133338936 1.670 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr19_-_8929323 1.649 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr1_-_155146755 1.628 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr8_+_33653238 1.618 ENSMUST00000033992.8
Gsr
glutathione reductase
chr1_-_167285110 1.594 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr11_+_60537978 1.546 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr17_-_45573253 1.487 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr4_-_140774196 1.486 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chr17_+_78491549 1.477 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr17_-_25868727 1.458 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr18_+_73863672 1.428 ENSMUST00000134847.1
Mro
maestro
chr16_+_90220742 1.421 ENSMUST00000023707.9
Sod1
superoxide dismutase 1, soluble
chr2_+_152105722 1.400 ENSMUST00000099225.2
Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr9_+_66126611 1.392 ENSMUST00000034945.5
Fam96a
family with sequence similarity 96, member A
chr1_-_120074023 1.381 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr18_-_34954302 1.355 ENSMUST00000025217.8
Hspa9
heat shock protein 9
chr14_+_67716095 1.351 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr16_+_20651652 1.342 ENSMUST00000007212.8
Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr17_-_24644933 1.327 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr12_+_17544873 1.322 ENSMUST00000171737.1
Odc1
ornithine decarboxylase, structural 1
chr7_-_104315455 1.289 ENSMUST00000106837.1
ENSMUST00000106839.2
ENSMUST00000070943.6
Trim12a


tripartite motif-containing 12A


chr2_+_91054009 1.288 ENSMUST00000067663.7
Psmc3
proteasome (prosome, macropain) 26S subunit, ATPase 3
chrX_+_159372175 1.279 ENSMUST00000087143.6
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
chr9_-_86695897 1.211 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr19_+_23675839 1.205 ENSMUST00000056396.5
Gm6563
predicted pseudogene 6563
chr4_-_126321669 1.204 ENSMUST00000102617.4
Adprhl2
ADP-ribosylhydrolase like 2
chr12_+_16810940 1.174 ENSMUST00000020908.7
E2f6
E2F transcription factor 6
chr2_+_120609383 1.173 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr7_-_105482197 1.152 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr5_-_65428354 1.147 ENSMUST00000131263.1
Ugdh
UDP-glucose dehydrogenase
chr16_+_20548577 1.138 ENSMUST00000003319.5
Abcf3
ATP-binding cassette, sub-family F (GCN20), member 3
chr4_-_43558386 1.137 ENSMUST00000130353.1
Tln1
talin 1
chr4_+_41569775 1.121 ENSMUST00000102963.3
Dnaic1
dynein, axonemal, intermediate chain 1
chrX_-_38252398 1.095 ENSMUST00000089056.3
ENSMUST00000089054.4
ENSMUST00000066498.7
Tmem255a


transmembrane protein 255A


chr14_-_20393473 1.092 ENSMUST00000061444.3
Mrps16
mitochondrial ribosomal protein S16
chr3_+_122245625 1.080 ENSMUST00000178826.1
Gclm
glutamate-cysteine ligase, modifier subunit
chr2_+_91054054 1.065 ENSMUST00000002171.7
ENSMUST00000111441.3
Psmc3

proteasome (prosome, macropain) 26S subunit, ATPase 3

chr2_+_112261926 1.055 ENSMUST00000028553.3
Nop10
NOP10 ribonucleoprotein
chr19_+_8929628 1.047 ENSMUST00000096241.4
Eml3
echinoderm microtubule associated protein like 3
chr5_+_137758133 1.044 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr5_+_100798627 1.027 ENSMUST00000016977.8
ENSMUST00000112898.1
ENSMUST00000112901.1
Mrps18c


mitochondrial ribosomal protein S18C


chr19_-_4037910 1.004 ENSMUST00000169613.1
Gstp1
glutathione S-transferase, pi 1
chr8_-_107588392 1.002 ENSMUST00000044106.4
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr9_+_65214690 0.994 ENSMUST00000069000.7
Parp16
poly (ADP-ribose) polymerase family, member 16
chr7_-_104353328 0.982 ENSMUST00000130139.1
ENSMUST00000059037.8
Trim12c

tripartite motif-containing 12C

chr9_-_42461414 0.979 ENSMUST00000066179.7
Tbcel
tubulin folding cofactor E-like
chr11_-_50325599 0.978 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr15_-_79605084 0.970 ENSMUST00000023065.6
Dmc1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
chr5_+_31698050 0.952 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
Bre



brain and reproductive organ-expressed protein



chr7_+_28881656 0.950 ENSMUST00000066880.4
Capn12
calpain 12
chr11_+_78178651 0.945 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr12_+_55398775 0.923 ENSMUST00000021412.8
Psma6
proteasome (prosome, macropain) subunit, alpha type 6
chr9_+_86695542 0.922 ENSMUST00000150367.2
A330041J22Rik
RIKEN cDNA A330041J22 gene
chr5_+_138187485 0.919 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr4_+_130047840 0.875 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr10_+_128058974 0.855 ENSMUST00000084771.2
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr11_-_74723829 0.835 ENSMUST00000102520.2
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr2_-_181691771 0.834 ENSMUST00000108778.1
ENSMUST00000165416.1
Rgs19

regulator of G-protein signaling 19

chr10_+_128058947 0.821 ENSMUST00000052798.7
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr12_-_40248073 0.795 ENSMUST00000169926.1
Ifrd1
interferon-related developmental regulator 1
chr11_+_107479549 0.792 ENSMUST00000106750.4
Psmd12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr3_+_108256926 0.782 ENSMUST00000090569.5
Psma5
proteasome (prosome, macropain) subunit, alpha type 5
chr7_-_17056669 0.779 ENSMUST00000037762.4
Hif3a
hypoxia inducible factor 3, alpha subunit
chr8_+_69822429 0.771 ENSMUST00000164890.1
ENSMUST00000034325.4
Lpar2

lysophosphatidic acid receptor 2

chr5_+_31697960 0.768 ENSMUST00000114515.2
Bre
brain and reproductive organ-expressed protein
chr2_-_120609319 0.724 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr7_-_29180699 0.717 ENSMUST00000059642.10
Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr11_+_107479478 0.711 ENSMUST00000021063.6
ENSMUST00000106752.3
Psmd12

proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

chr9_+_107578887 0.683 ENSMUST00000149638.1
ENSMUST00000139274.1
ENSMUST00000130053.1
ENSMUST00000122985.1
ENSMUST00000127380.1
ENSMUST00000139581.1
Nat6





N-acetyltransferase 6





chr5_+_30013141 0.679 ENSMUST00000026845.7
Il6
interleukin 6
chr7_-_29180454 0.675 ENSMUST00000182328.1
Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr11_+_80428598 0.670 ENSMUST00000173938.1
ENSMUST00000017572.7
Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr6_-_8259098 0.660 ENSMUST00000012627.4
Rpa3
replication protein A3
chr4_-_133874682 0.631 ENSMUST00000168974.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr2_+_116900152 0.621 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr7_-_114276107 0.618 ENSMUST00000033008.9
Psma1
proteasome (prosome, macropain) subunit, alpha type 1
chr2_-_120609283 0.617 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr19_-_4839286 0.614 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chrX_+_71050160 0.610 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr16_+_58727910 0.609 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chr5_-_45450221 0.606 ENSMUST00000015950.5
Qdpr
quinoid dihydropteridine reductase
chr7_+_45639964 0.596 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr2_-_25272380 0.527 ENSMUST00000028342.6
Ssna1
Sjogren's syndrome nuclear autoantigen 1
chr7_+_19083842 0.522 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
Dmpk



dystrophia myotonica-protein kinase



chr14_-_54617993 0.512 ENSMUST00000022803.4
Psmb5
proteasome (prosome, macropain) subunit, beta type 5
chr2_-_120609500 0.507 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr5_-_138187177 0.505 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr6_+_95117740 0.489 ENSMUST00000032107.7
ENSMUST00000119582.1
Kbtbd8

kelch repeat and BTB (POZ) domain containing 8

chr8_-_105326252 0.481 ENSMUST00000070508.7
Lrrc29
leucine rich repeat containing 29
chr8_+_94984399 0.479 ENSMUST00000093271.6
Gpr56
G protein-coupled receptor 56
chr7_+_139834148 0.469 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr15_+_84669565 0.466 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr6_-_30509706 0.462 ENSMUST00000064330.6
ENSMUST00000102991.2
ENSMUST00000115157.1
ENSMUST00000148638.1
Tmem209



transmembrane protein 209



chr14_+_26514554 0.451 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr7_+_102225812 0.441 ENSMUST00000142873.1
Pgap2
post-GPI attachment to proteins 2
chr9_+_27030159 0.402 ENSMUST00000073127.7
ENSMUST00000086198.4
Ncapd3

non-SMC condensin II complex, subunit D3

chr5_-_108675569 0.396 ENSMUST00000051757.7
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr15_+_80255184 0.381 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr13_+_14613242 0.373 ENSMUST00000170836.2
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr4_+_130047914 0.362 ENSMUST00000142293.1
Col16a1
collagen, type XVI, alpha 1
chr14_-_37135310 0.331 ENSMUST00000165649.2
Ghitm
growth hormone inducible transmembrane protein
chr11_+_120673359 0.315 ENSMUST00000135346.1
ENSMUST00000127269.1
ENSMUST00000131727.2
ENSMUST00000149389.1
ENSMUST00000153346.1
Aspscr1




alveolar soft part sarcoma chromosome region, candidate 1 (human)




chr7_+_127800604 0.312 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr17_-_45572495 0.308 ENSMUST00000130406.1
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr9_-_116175318 0.287 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr18_-_43477764 0.282 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr19_-_4042165 0.282 ENSMUST00000042700.9
Gstp2
glutathione S-transferase, pi 2
chr14_-_34374617 0.265 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr5_-_100798468 0.261 ENSMUST00000133845.1
ENSMUST00000044684.7
Helq

helicase, POLQ-like

chr14_+_120478443 0.241 ENSMUST00000062117.6
Rap2a
RAS related protein 2a
chr4_+_117251951 0.235 ENSMUST00000062824.5
Tmem53
transmembrane protein 53
chr17_+_34032348 0.204 ENSMUST00000173354.1
ENSMUST00000116612.2
Rxrb

retinoid X receptor beta

chr18_+_35598607 0.150 ENSMUST00000041314.8
ENSMUST00000115737.1
ENSMUST00000115736.1
ENSMUST00000115735.1
Paip2



polyadenylate-binding protein-interacting protein 2



chr1_-_168431695 0.145 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr3_+_27182994 0.135 ENSMUST00000091284.4
Nceh1
neutral cholesterol ester hydrolase 1
chr13_-_107890059 0.134 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr19_-_4334001 0.129 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr2_+_25272475 0.117 ENSMUST00000028341.4
Anapc2
anaphase promoting complex subunit 2
chr3_+_122245557 0.112 ENSMUST00000029769.7
Gclm
glutamate-cysteine ligase, modifier subunit
chr7_-_98145472 0.107 ENSMUST00000098281.2
Omp
olfactory marker protein
chr4_+_117252010 0.096 ENSMUST00000125943.1
ENSMUST00000106434.1
Tmem53

transmembrane protein 53

chr11_+_100619217 0.091 ENSMUST00000107376.1
Nkiras2
NFKB inhibitor interacting Ras-like protein 2
chr17_-_26939464 0.081 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr17_+_28951950 0.068 ENSMUST00000153462.1
Kctd20
potassium channel tetramerisation domain containing 20
chr7_+_44468020 0.067 ENSMUST00000117324.1
ENSMUST00000120852.1
ENSMUST00000118628.1
Josd2


Josephin domain containing 2


chr2_+_54436317 0.060 ENSMUST00000112636.1
ENSMUST00000112635.1
ENSMUST00000112634.1
Galnt13


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13


chr5_-_45450143 0.060 ENSMUST00000154962.1
Qdpr
quinoid dihydropteridine reductase
chr7_+_127800844 0.051 ENSMUST00000106271.1
ENSMUST00000138432.1
Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chrX_+_71962971 0.044 ENSMUST00000048790.6
Prrg3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr5_-_45450121 0.031 ENSMUST00000127562.1
Qdpr
quinoid dihydropteridine reductase
chr2_-_163419508 0.006 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chrX_-_97377150 0.001 ENSMUST00000113832.1
Eda2r
ectodysplasin A2 receptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0072180 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
1.7 16.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.4 4.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
1.3 3.8 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
1.2 3.5 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.1 3.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.9 2.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.8 2.5 GO:0072034 renal vesicle induction(GO:0072034)
0.7 7.1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.7 5.4 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.7 2.6 GO:0048819 positive regulation of keratinocyte proliferation(GO:0010838) regulation of hair follicle maturation(GO:0048819) regulation of catagen(GO:0051794)
0.6 2.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.6 1.8 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.5 1.6 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.5 0.5 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.5 13.0 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.4 1.3 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.4 7.5 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.4 1.5 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.4 1.2 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.4 1.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.4 1.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 1.0 GO:0070488 neutrophil aggregation(GO:0070488)
0.3 2.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 1.8 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.2 1.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 1.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 1.9 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.2 0.7 GO:0002295 T-helper cell lineage commitment(GO:0002295)
0.2 5.8 GO:0030224 monocyte differentiation(GO:0030224)
0.2 3.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 2.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 1.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 2.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 0.8 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.2 1.5 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 4.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 1.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.0 GO:0042148 strand invasion(GO:0042148)
0.1 1.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 2.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 1.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.6 GO:0032620 interleukin-17 production(GO:0032620)
0.1 0.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.3 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 1.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.8 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 0.4 GO:0019532 oxalate transport(GO:0019532)
0.1 2.5 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 1.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.7 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.8 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.7 GO:0006298 mismatch repair(GO:0006298)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.9 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 1.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 2.1 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.6 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.0 GO:0006970 response to osmotic stress(GO:0006970)
0.0 1.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.8 GO:0070482 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293) response to oxygen levels(GO:0070482)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 16.6 GO:0035686 sperm fibrous sheath(GO:0035686)
1.1 3.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.9 2.6 GO:0014802 terminal cisterna(GO:0014802)
0.5 2.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.3 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.4 1.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.4 3.9 GO:0031595 nuclear proteasome complex(GO:0031595)
0.4 1.2 GO:0005901 caveola(GO:0005901)
0.4 9.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 1.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 3.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 8.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 1.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 1.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 3.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.2 2.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 1.7 GO:0070552 BRISC complex(GO:0070552)
0.2 1.0 GO:1990462 omegasome(GO:1990462)
0.2 1.1 GO:0036157 outer dynein arm(GO:0036157)
0.2 1.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.2 GO:0070652 HAUS complex(GO:0070652)
0.1 0.8 GO:0000235 astral microtubule(GO:0000235)
0.1 1.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.9 GO:0016460 myosin II complex(GO:0016460)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 1.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.4 GO:0031045 dense core granule(GO:0031045)
0.1 1.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.9 GO:0005605 basal lamina(GO:0005605)
0.1 1.0 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
0.1 2.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.3 GO:0005884 actin filament(GO:0005884)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:1904949 ATPase complex(GO:1904949)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 2.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.6 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 16.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.0 4.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.8 9.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.8 3.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.7 3.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.6 3.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.6 7.5 GO:0005522 profilin binding(GO:0005522)
0.5 4.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.5 2.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 5.8 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 1.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.4 3.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.4 1.2 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.4 1.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.4 1.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.4 1.5 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.4 1.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.4 2.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.3 1.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.3 7.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 1.8 GO:0002135 CTP binding(GO:0002135)
0.3 2.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 2.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 1.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 5.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 3.7 GO:0010181 FMN binding(GO:0010181)
0.2 0.7 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.2 1.9 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.2 3.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 3.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 3.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.1 2.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.0 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 1.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 7.1 GO:0002039 p53 binding(GO:0002039)
0.1 0.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.6 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 3.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.4 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 1.9 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.7 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 4.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)