Motif ID: Nfic_Nfib
Z-value: 2.141
Transcription factors associated with Nfic_Nfib:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nfib | ENSMUSG00000008575.11 | Nfib |
Nfic | ENSMUSG00000055053.11 | Nfic |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nfic | mm10_v2_chr10_-_81430966_81431039 | 0.63 | 3.6e-09 | Click! |
Nfib | mm10_v2_chr4_-_82505274_82505358 | 0.14 | 2.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.4 | 52.1 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
8.1 | 48.6 | GO:1902847 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) |
7.5 | 74.5 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
7.2 | 36.2 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
6.8 | 20.4 | GO:0006553 | lysine metabolic process(GO:0006553) |
6.4 | 32.0 | GO:1900085 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) |
6.1 | 18.4 | GO:0051933 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
5.9 | 5.9 | GO:1903977 | positive regulation of glial cell migration(GO:1903977) |
5.8 | 23.3 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
5.0 | 20.0 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
4.6 | 37.1 | GO:0070314 | G1 to G0 transition(GO:0070314) |
4.5 | 18.1 | GO:0010046 | arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046) |
4.4 | 30.5 | GO:0015840 | urea transport(GO:0015840) urea transmembrane transport(GO:0071918) |
4.0 | 12.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
3.8 | 15.1 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
3.6 | 21.5 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
3.5 | 62.2 | GO:0060134 | prepulse inhibition(GO:0060134) |
3.4 | 10.3 | GO:0043465 | regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003) |
3.3 | 19.6 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
3.1 | 9.2 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
2.9 | 8.7 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
2.8 | 17.1 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
2.8 | 16.8 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
2.5 | 17.8 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
2.4 | 23.7 | GO:0009404 | toxin metabolic process(GO:0009404) |
2.2 | 10.9 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
2.0 | 36.5 | GO:0032060 | bleb assembly(GO:0032060) |
2.0 | 5.9 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) |
2.0 | 31.3 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
1.9 | 5.7 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
1.8 | 9.1 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
1.8 | 10.6 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
1.8 | 8.8 | GO:0042167 | heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
1.6 | 14.6 | GO:0042940 | D-amino acid transport(GO:0042940) |
1.6 | 9.6 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
1.6 | 6.4 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
1.6 | 7.9 | GO:1902947 | regulation of tau-protein kinase activity(GO:1902947) |
1.6 | 17.3 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
1.5 | 4.6 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
1.5 | 10.7 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
1.5 | 4.5 | GO:0006533 | aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478) |
1.5 | 14.7 | GO:0031639 | plasminogen activation(GO:0031639) |
1.4 | 5.6 | GO:1903898 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
1.4 | 9.5 | GO:0000022 | mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256) |
1.3 | 6.7 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
1.3 | 8.0 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
1.3 | 3.9 | GO:0030070 | insulin processing(GO:0030070) |
1.3 | 11.5 | GO:0006691 | leukotriene metabolic process(GO:0006691) |
1.2 | 6.2 | GO:0070166 | enamel mineralization(GO:0070166) |
1.2 | 13.4 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
1.1 | 4.6 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
1.1 | 11.1 | GO:0046415 | urate metabolic process(GO:0046415) |
1.1 | 3.3 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
1.1 | 7.6 | GO:0048251 | elastic fiber assembly(GO:0048251) |
1.1 | 3.2 | GO:0003032 | detection of oxygen(GO:0003032) |
1.0 | 26.5 | GO:0033622 | integrin activation(GO:0033622) |
1.0 | 4.0 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
1.0 | 6.9 | GO:0051461 | positive regulation of heat generation(GO:0031652) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
1.0 | 11.6 | GO:0046697 | decidualization(GO:0046697) |
0.9 | 1.8 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.9 | 9.1 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
0.9 | 2.7 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.9 | 5.4 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
0.9 | 1.8 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
0.9 | 1.7 | GO:0021759 | globus pallidus development(GO:0021759) |
0.8 | 7.6 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.8 | 3.4 | GO:0007113 | endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256) |
0.8 | 5.6 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
0.8 | 5.5 | GO:0001880 | Mullerian duct regression(GO:0001880) |
0.8 | 2.3 | GO:0070649 | meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649) |
0.8 | 4.5 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.8 | 1.5 | GO:0006566 | threonine metabolic process(GO:0006566) |
0.7 | 17.2 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
0.7 | 4.2 | GO:0009169 | purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) |
0.7 | 8.0 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
0.7 | 12.6 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.7 | 4.6 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
0.6 | 21.8 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.6 | 5.1 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
0.6 | 10.7 | GO:0014823 | response to activity(GO:0014823) |
0.6 | 6.1 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.6 | 15.4 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
0.6 | 3.4 | GO:0071455 | cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455) |
0.6 | 3.4 | GO:2001185 | regulation of CD8-positive, alpha-beta T cell activation(GO:2001185) |
0.5 | 5.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.5 | 2.0 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
0.5 | 24.3 | GO:0048678 | response to axon injury(GO:0048678) |
0.5 | 1.0 | GO:0014887 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
0.4 | 3.8 | GO:0051409 | response to nitrosative stress(GO:0051409) |
0.4 | 14.6 | GO:0060325 | face morphogenesis(GO:0060325) |
0.4 | 5.2 | GO:0010388 | cullin deneddylation(GO:0010388) |
0.4 | 22.8 | GO:0048747 | muscle fiber development(GO:0048747) |
0.3 | 13.1 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.3 | 3.1 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
0.3 | 2.0 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
0.3 | 1.3 | GO:0046210 | nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346) |
0.3 | 2.0 | GO:0002317 | plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.3 | 2.0 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.3 | 0.9 | GO:0097186 | amelogenesis(GO:0097186) |
0.3 | 0.6 | GO:0072138 | mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) |
0.3 | 1.7 | GO:0044351 | macropinocytosis(GO:0044351) |
0.3 | 17.0 | GO:0006970 | response to osmotic stress(GO:0006970) |
0.3 | 3.4 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
0.2 | 4.7 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
0.2 | 3.2 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.2 | 0.4 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.2 | 2.9 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.2 | 0.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.2 | 0.7 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
0.2 | 4.0 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.2 | 1.3 | GO:2000598 | regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599) |
0.2 | 4.1 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.2 | 1.0 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.2 | 7.2 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.1 | 10.1 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.1 | 5.1 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
0.1 | 3.1 | GO:0046185 | aldehyde catabolic process(GO:0046185) |
0.1 | 1.4 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 4.5 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
0.1 | 1.0 | GO:2000194 | regulation of female gonad development(GO:2000194) |
0.1 | 0.2 | GO:0010872 | regulation of cholesterol esterification(GO:0010872) |
0.1 | 1.0 | GO:1902913 | positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913) |
0.1 | 0.3 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
0.1 | 3.5 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.1 | 8.7 | GO:0007601 | visual perception(GO:0007601) |
0.1 | 1.3 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.1 | 1.0 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
0.1 | 0.8 | GO:1903608 | IRES-dependent viral translational initiation(GO:0075522) protein localization to cytoplasmic stress granule(GO:1903608) |
0.1 | 2.1 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
0.1 | 2.2 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.1 | 0.3 | GO:0030210 | heparin biosynthetic process(GO:0030210) |
0.1 | 8.1 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
0.1 | 0.8 | GO:0035336 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) |
0.1 | 0.2 | GO:0019336 | phenol-containing compound catabolic process(GO:0019336) |
0.1 | 2.7 | GO:0019915 | lipid storage(GO:0019915) |
0.1 | 0.2 | GO:0046013 | T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013) |
0.1 | 2.8 | GO:0003341 | cilium movement(GO:0003341) |
0.1 | 6.8 | GO:0007605 | sensory perception of sound(GO:0007605) |
0.1 | 2.6 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
0.1 | 0.9 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.1 | 0.2 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
0.1 | 0.2 | GO:0070488 | neutrophil aggregation(GO:0070488) |
0.1 | 0.5 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
0.1 | 0.3 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.0 | 0.5 | GO:0050878 | regulation of body fluid levels(GO:0050878) |
0.0 | 10.9 | GO:0048863 | stem cell differentiation(GO:0048863) |
0.0 | 0.1 | GO:0031424 | keratinization(GO:0031424) |
0.0 | 1.4 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.0 | 0.8 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
0.0 | 1.3 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
0.0 | 0.2 | GO:0034143 | regulation of toll-like receptor 4 signaling pathway(GO:0034143) |
0.0 | 0.5 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.0 | 0.1 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
0.0 | 1.1 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 1.3 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
0.0 | 0.2 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.0 | 0.6 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
0.0 | 2.7 | GO:0007219 | Notch signaling pathway(GO:0007219) |
0.0 | 0.1 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
0.0 | 0.9 | GO:0016064 | immunoglobulin mediated immune response(GO:0016064) |
0.0 | 0.0 | GO:0035811 | negative regulation of urine volume(GO:0035811) |
0.0 | 0.2 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
0.0 | 0.0 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
0.0 | 0.3 | GO:0016571 | histone methylation(GO:0016571) |
0.0 | 0.5 | GO:0030509 | BMP signaling pathway(GO:0030509) |
0.0 | 2.0 | GO:0051607 | defense response to virus(GO:0051607) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.9 | 48.6 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418) |
5.9 | 17.8 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
5.8 | 17.5 | GO:0005595 | collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934) |
5.4 | 21.5 | GO:0097450 | astrocyte end-foot(GO:0097450) |
5.3 | 15.8 | GO:0071953 | elastic fiber(GO:0071953) |
3.8 | 15.1 | GO:0045098 | type III intermediate filament(GO:0045098) |
3.2 | 28.6 | GO:0097449 | astrocyte projection(GO:0097449) |
2.7 | 10.7 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
2.1 | 32.0 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
2.1 | 12.6 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
2.0 | 5.9 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
1.8 | 7.2 | GO:0043259 | laminin-10 complex(GO:0043259) |
1.3 | 3.8 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
1.1 | 14.4 | GO:0070852 | cell body fiber(GO:0070852) |
1.1 | 8.5 | GO:0033269 | internode region of axon(GO:0033269) |
1.0 | 9.2 | GO:0008278 | cohesin complex(GO:0008278) |
1.0 | 8.0 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
1.0 | 10.6 | GO:0005915 | zonula adherens(GO:0005915) |
0.9 | 2.8 | GO:0036156 | inner dynein arm(GO:0036156) |
0.9 | 4.5 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.7 | 3.3 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.7 | 4.6 | GO:0042825 | TAP complex(GO:0042825) |
0.5 | 13.4 | GO:0002102 | podosome(GO:0002102) |
0.5 | 4.7 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.5 | 2.7 | GO:0030128 | clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669) |
0.4 | 11.2 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.4 | 5.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.4 | 2.0 | GO:0005861 | troponin complex(GO:0005861) |
0.4 | 8.3 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.4 | 8.0 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.4 | 27.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.3 | 24.1 | GO:0005581 | collagen trimer(GO:0005581) |
0.3 | 24.2 | GO:0005604 | basement membrane(GO:0005604) |
0.3 | 2.1 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.3 | 3.9 | GO:0031045 | dense core granule(GO:0031045) |
0.3 | 50.6 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.2 | 9.2 | GO:0031902 | late endosome membrane(GO:0031902) |
0.2 | 7.9 | GO:0030673 | axolemma(GO:0030673) |
0.2 | 3.4 | GO:0032433 | filopodium tip(GO:0032433) |
0.2 | 6.7 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
0.2 | 3.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.2 | 6.7 | GO:0097440 | apical dendrite(GO:0097440) |
0.2 | 8.8 | GO:0044297 | cell body(GO:0044297) |
0.2 | 12.0 | GO:0005844 | polysome(GO:0005844) |
0.2 | 7.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.2 | 2.0 | GO:0001527 | microfibril(GO:0001527) |
0.2 | 18.6 | GO:0005814 | centriole(GO:0005814) |
0.2 | 18.4 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.2 | 1.4 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.2 | 8.5 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
0.2 | 8.8 | GO:0005811 | lipid particle(GO:0005811) |
0.1 | 1.9 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 2.6 | GO:0001741 | XY body(GO:0001741) |
0.1 | 46.0 | GO:0043025 | neuronal cell body(GO:0043025) |
0.1 | 9.1 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.1 | 19.3 | GO:0042383 | sarcolemma(GO:0042383) |
0.1 | 5.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 5.1 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.1 | 110.7 | GO:0005615 | extracellular space(GO:0005615) |
0.1 | 2.3 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.1 | 4.2 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.1 | 43.1 | GO:0030424 | axon(GO:0030424) |
0.1 | 5.4 | GO:0072686 | mitotic spindle(GO:0072686) |
0.1 | 3.3 | GO:0005901 | caveola(GO:0005901) |
0.1 | 25.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 3.2 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 3.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 6.2 | GO:0005938 | cell cortex(GO:0005938) |
0.0 | 5.8 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 2.6 | GO:0031012 | extracellular matrix(GO:0031012) |
0.0 | 2.0 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 0.1 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 24.0 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.0 | 5.7 | GO:0005925 | focal adhesion(GO:0005925) |
0.0 | 0.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 1.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 37.1 | GO:0016021 | integral component of membrane(GO:0016021) |
0.0 | 2.2 | GO:0016023 | cytoplasmic, membrane-bounded vesicle(GO:0016023) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
12.9 | 77.5 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
9.1 | 36.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
6.4 | 32.0 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
6.1 | 18.4 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
5.1 | 20.4 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
5.1 | 30.5 | GO:0015265 | urea channel activity(GO:0015265) |
4.7 | 23.7 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
4.5 | 17.8 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
4.0 | 52.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
3.8 | 15.1 | GO:1990254 | keratin filament binding(GO:1990254) |
3.4 | 13.4 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
3.0 | 9.1 | GO:0035939 | microsatellite binding(GO:0035939) |
2.9 | 8.8 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
2.9 | 11.6 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
2.9 | 8.7 | GO:0003884 | D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922) |
2.8 | 41.7 | GO:0008430 | selenium binding(GO:0008430) |
2.7 | 10.9 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
2.2 | 8.8 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
2.2 | 2.2 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
2.1 | 8.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
2.1 | 48.6 | GO:0051787 | misfolded protein binding(GO:0051787) |
2.0 | 10.1 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
2.0 | 18.1 | GO:0015643 | toxic substance binding(GO:0015643) |
2.0 | 7.9 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
2.0 | 7.9 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
1.9 | 11.6 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
1.8 | 10.9 | GO:0019841 | retinol binding(GO:0019841) |
1.8 | 5.3 | GO:0008521 | acetyl-CoA transporter activity(GO:0008521) |
1.7 | 66.1 | GO:0005504 | fatty acid binding(GO:0005504) |
1.6 | 12.6 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
1.5 | 12.2 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
1.5 | 10.2 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
1.4 | 19.6 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
1.3 | 7.9 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
1.3 | 3.8 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
1.2 | 10.9 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
1.1 | 4.6 | GO:0023029 | peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980) |
1.1 | 26.8 | GO:0030506 | ankyrin binding(GO:0030506) |
1.1 | 3.2 | GO:0005534 | galactose binding(GO:0005534) |
0.9 | 5.7 | GO:0009374 | biotin binding(GO:0009374) |
0.9 | 5.6 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
0.9 | 10.6 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.8 | 11.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.8 | 9.2 | GO:0034943 | acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409) |
0.8 | 9.6 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.7 | 5.9 | GO:0004779 | sulfate adenylyltransferase activity(GO:0004779) |
0.7 | 2.9 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
0.7 | 2.0 | GO:0030172 | troponin C binding(GO:0030172) |
0.7 | 3.4 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.6 | 5.1 | GO:0051718 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718) |
0.6 | 6.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.6 | 1.8 | GO:0035175 | histone kinase activity (H3-S10 specific)(GO:0035175) |
0.6 | 3.1 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.6 | 4.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.6 | 60.6 | GO:0005178 | integrin binding(GO:0005178) |
0.5 | 4.7 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.5 | 4.7 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.5 | 1.5 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.5 | 13.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.5 | 6.7 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.4 | 1.8 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
0.4 | 5.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.4 | 17.2 | GO:0045309 | protein phosphorylated amino acid binding(GO:0045309) |
0.4 | 6.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.4 | 13.7 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
0.4 | 1.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.3 | 8.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.3 | 6.9 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.3 | 2.0 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
0.3 | 11.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.3 | 1.3 | GO:0016675 | oxidoreductase activity, acting on a heme group of donors(GO:0016675) |
0.3 | 2.0 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.3 | 8.1 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.3 | 3.2 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.3 | 23.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.3 | 15.6 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.3 | 8.0 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.3 | 1.4 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.2 | 9.2 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
0.2 | 0.7 | GO:0005118 | sevenless binding(GO:0005118) |
0.2 | 1.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.2 | 3.3 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.2 | 11.7 | GO:0019003 | GDP binding(GO:0019003) |
0.2 | 4.1 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) |
0.2 | 0.9 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.2 | 4.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.2 | 2.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.1 | 1.7 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.1 | 3.9 | GO:0004407 | histone deacetylase activity(GO:0004407) |
0.1 | 1.5 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 9.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.1 | 2.2 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.1 | 4.1 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.1 | 3.0 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
0.1 | 7.2 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.1 | 4.7 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.1 | 2.7 | GO:0030295 | protein kinase activator activity(GO:0030295) |
0.1 | 0.3 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) |
0.1 | 0.3 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
0.1 | 10.6 | GO:0015293 | symporter activity(GO:0015293) |
0.1 | 0.9 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
0.1 | 0.4 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.1 | 3.9 | GO:0020037 | heme binding(GO:0020037) |
0.1 | 5.9 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.1 | 2.7 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
0.0 | 0.8 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.6 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 3.4 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 3.2 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
0.0 | 1.3 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 1.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 7.3 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 0.7 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 1.8 | GO:0042281 | dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281) |
0.0 | 1.0 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 3.7 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.5 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
0.0 | 0.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.2 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.0 | 0.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 2.5 | GO:0003729 | mRNA binding(GO:0003729) |
0.0 | 0.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |