Motif ID: Nfic_Nfib

Z-value: 2.141

Transcription factors associated with Nfic_Nfib:

Gene SymbolEntrez IDGene Name
Nfib ENSMUSG00000008575.11 Nfib
Nfic ENSMUSG00000055053.11 Nfic

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nficmm10_v2_chr10_-_81430966_814310390.633.6e-09Click!
Nfibmm10_v2_chr4_-_82505274_825053580.142.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nfic_Nfib

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_78324200 55.085 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr6_+_135362931 39.053 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr10_+_57784859 38.818 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr1_+_43730593 37.136 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr18_-_80986578 31.262 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr6_-_115251839 29.573 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr8_+_72646679 28.070 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chr3_+_94933041 26.150 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr8_+_72646728 25.809 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chr16_+_90831113 25.269 ENSMUST00000037539.7
ENSMUST00000099543.3
Eva1c

eva-1 homolog C (C. elegans)

chr10_+_57784914 23.430 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr6_+_17306335 23.375 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr11_+_3488275 23.346 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr10_+_86302854 23.066 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr11_+_78322965 22.401 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr2_-_164404606 22.289 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
Matn4


matrilin 4


chr1_-_162859684 21.392 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr11_-_77894096 20.416 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr4_+_130047840 18.665 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr1_+_172341197 18.444 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr2_-_25470031 18.441 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr2_+_31470207 18.088 ENSMUST00000102840.4
Ass1
argininosuccinate synthetase 1
chr2_-_25469742 17.775 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr19_-_42752710 17.674 ENSMUST00000076505.3
Pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr3_+_94693556 17.312 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr14_-_118052235 17.072 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr7_+_130936172 16.816 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr18_-_78123324 15.873 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr6_+_29433248 15.836 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chr7_-_97417730 15.736 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr7_+_45017953 15.559 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr2_-_125723387 15.301 ENSMUST00000042246.7
Shc4
SHC (Src homology 2 domain containing) family, member 4
chr5_-_77115145 15.217 ENSMUST00000081964.5
Hopx
HOP homeobox
chr2_+_13573927 15.138 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr11_-_116110211 14.757 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr8_+_22757744 14.664 ENSMUST00000033941.5
Plat
plasminogen activator, tissue
chr3_-_116129615 13.414 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr14_+_65971049 12.568 ENSMUST00000128539.1
Clu
clusterin
chr14_+_65970610 12.479 ENSMUST00000127387.1
Clu
clusterin
chr11_+_109485606 12.160 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr11_-_102897123 12.158 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr11_+_3989924 12.124 ENSMUST00000109981.1
Gal3st1
galactose-3-O-sulfotransferase 1
chr11_-_94601862 11.937 ENSMUST00000103164.3
Acsf2
acyl-CoA synthetase family member 2
chr18_-_78206408 11.881 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr14_+_65971164 11.843 ENSMUST00000144619.1
Clu
clusterin
chr14_+_65970804 11.692 ENSMUST00000138191.1
Clu
clusterin
chr4_+_41762309 11.621 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr9_-_54661870 11.566 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr6_-_24956106 11.350 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr9_+_44134562 10.958 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr7_-_79386943 10.940 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr6_+_29433131 10.940 ENSMUST00000090474.4
Flnc
filamin C, gamma
chr1_-_120120138 10.899 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr3_-_131272077 10.898 ENSMUST00000029610.8
Hadh
hydroxyacyl-Coenzyme A dehydrogenase
chr1_-_72874877 10.746 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr7_-_116237767 10.649 ENSMUST00000182834.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr14_-_122451109 10.584 ENSMUST00000081580.2
Gm5089
predicted gene 5089
chr7_-_105482197 10.277 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr5_-_9725305 10.110 ENSMUST00000004076.3
Grm3
glutamate receptor, metabotropic 3
chr3_+_57736056 10.103 ENSMUST00000041826.9
Rnf13
ring finger protein 13
chr2_+_165503787 9.627 ENSMUST00000029196.4
Slc2a10
solute carrier family 2 (facilitated glucose transporter), member 10
chrX_+_166238901 9.617 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr2_+_152754156 9.544 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr11_-_102897146 9.358 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr5_+_137758133 9.327 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr9_+_69453620 9.308 ENSMUST00000034756.8
ENSMUST00000123470.1
Anxa2

annexin A2

chr19_+_6084983 9.207 ENSMUST00000025704.2
Cdca5
cell division cycle associated 5
chr6_+_120773633 9.175 ENSMUST00000112682.2
Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr14_+_54259227 9.173 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr3_-_8667033 9.149 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr13_+_74639866 9.144 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr7_+_27447978 8.826 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr9_-_21798502 8.694 ENSMUST00000034717.5
Kank2
KN motif and ankyrin repeat domains 2
chr11_-_110095937 8.678 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr6_+_17306415 8.647 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr9_+_69454066 8.529 ENSMUST00000134907.1
Anxa2
annexin A2
chr18_+_82554463 8.461 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp










myelin basic protein










chr12_-_80132802 8.335 ENSMUST00000180643.1
2310015A10Rik
RIKEN cDNA 2310015A10 gene
chr5_-_134747241 8.182 ENSMUST00000015138.9
Eln
elastin
chrX_+_166238923 8.149 ENSMUST00000060210.7
ENSMUST00000112233.1
Gpm6b

glycoprotein m6b

chr2_+_129592818 8.045 ENSMUST00000153491.1
ENSMUST00000161620.1
ENSMUST00000179001.1
Sirpa


signal-regulatory protein alpha


chr5_+_16553488 7.903 ENSMUST00000030683.3
Hgf
hepatocyte growth factor
chr14_+_62332068 7.879 ENSMUST00000022499.6
Rnaseh2b
ribonuclease H2, subunit B
chr7_+_30553263 7.876 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr1_-_5019342 7.869 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr2_+_102658640 7.851 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_+_61485431 7.606 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr1_+_185454803 7.589 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr17_+_32685655 7.256 ENSMUST00000008801.6
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr2_-_180225812 7.224 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr4_+_130047914 7.173 ENSMUST00000142293.1
Col16a1
collagen, type XVI, alpha 1
chr2_-_105399286 7.109 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr5_-_38480131 7.054 ENSMUST00000143758.1
ENSMUST00000067886.5
Slc2a9

solute carrier family 2 (facilitated glucose transporter), member 9

chrX_-_48034842 6.860 ENSMUST00000039026.7
Apln
apelin
chr17_-_32947372 6.772 ENSMUST00000139353.1
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr7_+_35186370 6.706 ENSMUST00000135452.1
ENSMUST00000001854.5
Slc7a10

solute carrier family 7 (cationic amino acid transporter, y+ system), member 10

chr10_+_3740348 6.564 ENSMUST00000120274.1
Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr13_-_97747373 6.563 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr9_-_79718631 6.530 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr6_+_138141569 6.413 ENSMUST00000118091.1
Mgst1
microsomal glutathione S-transferase 1
chr14_+_70530819 6.412 ENSMUST00000047331.6
Lgi3
leucine-rich repeat LGI family, member 3
chr11_-_109722214 6.244 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr2_+_129592914 6.187 ENSMUST00000103203.1
Sirpa
signal-regulatory protein alpha
chr2_-_26122769 6.081 ENSMUST00000140993.1
ENSMUST00000028300.5
Nacc2

nucleus accumbens associated 2, BEN and BTB (POZ) domain containing

chr7_-_142578139 5.930 ENSMUST00000136359.1
H19
H19 fetal liver mRNA
chr3_-_107760221 5.927 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr4_-_63403330 5.924 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr7_-_142576492 5.886 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr19_+_32619997 5.882 ENSMUST00000025833.6
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr5_+_137745967 5.845 ENSMUST00000100539.3
Tsc22d4
TSC22 domain family, member 4
chr9_-_79718518 5.771 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr19_+_4594312 5.669 ENSMUST00000113825.2
Pcx
pyruvate carboxylase
chr7_-_118995211 5.635 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr9_-_100506844 5.586 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr5_-_110286159 5.574 ENSMUST00000031472.5
Pxmp2
peroxisomal membrane protein 2
chr3_+_54755574 5.498 ENSMUST00000029371.2
Smad9
SMAD family member 9
chr7_-_142578093 5.477 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr15_-_103366763 5.402 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr11_-_115612491 5.260 ENSMUST00000106507.2
Mif4gd
MIF4G domain containing
chr11_+_115154139 5.199 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr9_-_79718720 5.174 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr11_-_82991829 5.104 ENSMUST00000092840.4
ENSMUST00000038211.5
Slfn9

schlafen 9

chr12_+_3891728 5.101 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr2_-_118762607 5.095 ENSMUST00000059997.8
A430105I19Rik
RIKEN cDNA A430105I19 gene
chr15_+_74563738 4.953 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr3_-_116423930 4.935 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr8_-_67818284 4.909 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr16_+_91406235 4.828 ENSMUST00000023691.5
Il10rb
interleukin 10 receptor, beta
chr17_+_28272191 4.788 ENSMUST00000169040.1
Ppard
peroxisome proliferator activator receptor delta
chr17_-_32947389 4.770 ENSMUST00000075253.6
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr3_-_57294880 4.737 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr9_-_106199253 4.731 ENSMUST00000140761.1
Ppm1m
protein phosphatase 1M
chr7_-_134232005 4.712 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr14_+_62292475 4.685 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr14_-_62454793 4.678 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr4_+_15265798 4.616 ENSMUST00000062684.8
Tmem64
transmembrane protein 64
chr3_-_116424007 4.607 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr17_+_34203527 4.584 ENSMUST00000025197.5
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_+_71673255 4.544 ENSMUST00000097284.3
Fam179a
family with sequence similarity 179, member A
chr5_+_110286306 4.521 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr12_-_91746020 4.487 ENSMUST00000166967.1
Ston2
stonin 2
chr10_+_40629987 4.468 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr6_-_83033422 4.340 ENSMUST00000089651.5
Dok1
docking protein 1
chr11_-_3539228 4.273 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
Smtn



smoothelin



chr9_+_88327592 4.246 ENSMUST00000034992.6
Nt5e
5' nucleotidase, ecto
chr8_+_94977101 4.239 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr6_+_83034173 4.223 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr11_-_82991137 4.172 ENSMUST00000138797.1
Slfn9
schlafen 9
chr3_-_104818539 4.133 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr5_+_64812336 4.098 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr1_+_51289106 4.082 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr2_+_30078584 4.076 ENSMUST00000045246.7
Pkn3
protein kinase N3
chr7_-_134232125 4.061 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr13_-_98815408 4.044 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr3_-_63851251 3.968 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr8_-_64693027 3.938 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr5_+_137745730 3.882 ENSMUST00000100540.3
Tsc22d4
TSC22 domain family, member 4
chr10_-_105574435 3.841 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr2_-_104742802 3.797 ENSMUST00000028595.7
Depdc7
DEP domain containing 7
chr4_+_141239499 3.712 ENSMUST00000141834.2
Arhgef19
Rho guanine nucleotide exchange factor (GEF) 19
chr10_+_59879617 3.702 ENSMUST00000142819.1
ENSMUST00000020309.6
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr5_-_5514730 3.604 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr3_+_41742615 3.582 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr4_-_93335510 3.553 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr1_-_88277510 3.438 ENSMUST00000065420.5
ENSMUST00000054674.8
Hjurp

Holliday junction recognition protein

chr3_+_52268337 3.404 ENSMUST00000053764.5
Foxo1
forkhead box O1
chr3_-_89393294 3.385 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr2_-_26604267 3.368 ENSMUST00000028286.5
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr11_-_70656467 3.319 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr4_-_9643638 3.301 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
Asph




aspartate-beta-hydroxylase




chr1_-_88277470 3.223 ENSMUST00000147393.1
Hjurp
Holliday junction recognition protein
chr5_-_116288978 3.222 ENSMUST00000050178.6
Ccdc60
coiled-coil domain containing 60
chr6_+_83142387 3.186 ENSMUST00000130622.1
ENSMUST00000129316.1
Rtkn

rhotekin

chr14_+_79481164 3.185 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr3_+_95228952 3.177 ENSMUST00000107201.2
Cdc42se1
CDC42 small effector 1
chr2_+_32646586 3.174 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr5_-_5514873 3.147 ENSMUST00000060947.7
Cldn12
claudin 12
chr11_+_78178651 3.104 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr19_-_3929723 3.074 ENSMUST00000051803.6
Aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr3_-_63964768 3.055 ENSMUST00000029402.8
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr3_+_135825648 3.043 ENSMUST00000180196.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr9_+_64117147 2.961 ENSMUST00000034969.7
Lctl
lactase-like
chr2_+_129593195 2.957 ENSMUST00000099113.3
ENSMUST00000103202.3
Sirpa

signal-regulatory protein alpha

chr13_-_115101909 2.927 ENSMUST00000061673.7
Itga1
integrin alpha 1
chr7_-_19770509 2.878 ENSMUST00000003061.7
Bcam
basal cell adhesion molecule
chr6_-_73221625 2.841 ENSMUST00000064948.6
ENSMUST00000114040.1
Dnah6

dynein, axonemal, heavy chain 6

chr11_-_110095974 2.812 ENSMUST00000100287.2
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr15_+_102102926 2.807 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr2_+_76650264 2.796 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr9_-_71163224 2.739 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr11_-_61579637 2.726 ENSMUST00000147501.1
ENSMUST00000146455.1
ENSMUST00000108711.1
ENSMUST00000108712.1
ENSMUST00000001063.8
ENSMUST00000108713.1
ENSMUST00000179936.1
ENSMUST00000178202.1
Epn2







epsin 2







chr5_-_34513892 2.709 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr17_-_35027909 2.704 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr2_-_93849679 2.701 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
Accs


1-aminocyclopropane-1-carboxylate synthase (non-functional)


chr3_+_135826075 2.623 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr13_-_34994103 2.562 ENSMUST00000171258.1
ENSMUST00000170989.1
ENSMUST00000021854.6
ENSMUST00000110251.2
ENSMUST00000167036.1
ENSMUST00000171229.1
ENSMUST00000178421.1
Eci2






enoyl-Coenzyme A delta isomerase 2






chr5_+_24426831 2.451 ENSMUST00000155598.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr5_+_52582320 2.389 ENSMUST00000177881.1
Gm5866
predicted gene 5866
chr2_+_164832862 2.360 ENSMUST00000103093.3
ENSMUST00000017904.2
Ctsa

cathepsin A

chr5_+_9266097 2.348 ENSMUST00000134991.1
ENSMUST00000069538.7
ENSMUST00000115348.2
9330182L06Rik


RIKEN cDNA 9330182L06 gene



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 52.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
8.1 48.6 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
7.5 74.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
7.2 36.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
6.8 20.4 GO:0006553 lysine metabolic process(GO:0006553)
6.4 32.0 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
6.1 18.4 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
5.9 5.9 GO:1903977 positive regulation of glial cell migration(GO:1903977)
5.8 23.3 GO:0019372 lipoxygenase pathway(GO:0019372)
5.0 20.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
4.6 37.1 GO:0070314 G1 to G0 transition(GO:0070314)
4.5 18.1 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
4.4 30.5 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
4.0 12.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
3.8 15.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
3.6 21.5 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
3.5 62.2 GO:0060134 prepulse inhibition(GO:0060134)
3.4 10.3 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
3.3 19.6 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
3.1 9.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
2.9 8.7 GO:1901420 negative regulation of response to alcohol(GO:1901420)
2.8 17.1 GO:0006570 tyrosine metabolic process(GO:0006570)
2.8 16.8 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
2.5 17.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.4 23.7 GO:0009404 toxin metabolic process(GO:0009404)
2.2 10.9 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
2.0 36.5 GO:0032060 bleb assembly(GO:0032060)
2.0 5.9 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
2.0 31.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
1.9 5.7 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.8 9.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
1.8 10.6 GO:0045218 zonula adherens maintenance(GO:0045218)
1.8 8.8 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.6 14.6 GO:0042940 D-amino acid transport(GO:0042940)
1.6 9.6 GO:0035428 hexose transmembrane transport(GO:0035428)
1.6 6.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
1.6 7.9 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
1.6 17.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
1.5 4.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
1.5 10.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.5 4.5 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478)
1.5 14.7 GO:0031639 plasminogen activation(GO:0031639)
1.4 5.6 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
1.4 9.5 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
1.3 6.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.3 8.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.3 3.9 GO:0030070 insulin processing(GO:0030070)
1.3 11.5 GO:0006691 leukotriene metabolic process(GO:0006691)
1.2 6.2 GO:0070166 enamel mineralization(GO:0070166)
1.2 13.4 GO:0061032 visceral serous pericardium development(GO:0061032)
1.1 4.6 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.1 11.1 GO:0046415 urate metabolic process(GO:0046415)
1.1 3.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.1 7.6 GO:0048251 elastic fiber assembly(GO:0048251)
1.1 3.2 GO:0003032 detection of oxygen(GO:0003032)
1.0 26.5 GO:0033622 integrin activation(GO:0033622)
1.0 4.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
1.0 6.9 GO:0051461 positive regulation of heat generation(GO:0031652) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
1.0 11.6 GO:0046697 decidualization(GO:0046697)
0.9 1.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.9 9.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.9 2.7 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.9 5.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.9 1.8 GO:0019401 alditol biosynthetic process(GO:0019401)
0.9 1.7 GO:0021759 globus pallidus development(GO:0021759)
0.8 7.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.8 3.4 GO:0007113 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.8 5.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.8 5.5 GO:0001880 Mullerian duct regression(GO:0001880)
0.8 2.3 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.8 4.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.8 1.5 GO:0006566 threonine metabolic process(GO:0006566)
0.7 17.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.7 4.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.7 8.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.7 12.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.7 4.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.6 21.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.6 5.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.6 10.7 GO:0014823 response to activity(GO:0014823)
0.6 6.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.6 15.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.6 3.4 GO:0071455 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.6 3.4 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.5 5.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.5 2.0 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.5 24.3 GO:0048678 response to axon injury(GO:0048678)
0.5 1.0 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.4 3.8 GO:0051409 response to nitrosative stress(GO:0051409)
0.4 14.6 GO:0060325 face morphogenesis(GO:0060325)
0.4 5.2 GO:0010388 cullin deneddylation(GO:0010388)
0.4 22.8 GO:0048747 muscle fiber development(GO:0048747)
0.3 13.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.3 3.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 2.0 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.3 1.3 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.3 2.0 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3 2.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 0.9 GO:0097186 amelogenesis(GO:0097186)
0.3 0.6 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.3 1.7 GO:0044351 macropinocytosis(GO:0044351)
0.3 17.0 GO:0006970 response to osmotic stress(GO:0006970)
0.3 3.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.2 4.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.2 3.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 0.4 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 2.9 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 0.7 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 4.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 1.3 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.2 4.1 GO:0006379 mRNA cleavage(GO:0006379)
0.2 1.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 7.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 10.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 5.1 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 3.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 1.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 4.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 1.0 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.2 GO:0010872 regulation of cholesterol esterification(GO:0010872)
0.1 1.0 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.1 0.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 3.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 8.7 GO:0007601 visual perception(GO:0007601)
0.1 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.0 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.8 GO:1903608 IRES-dependent viral translational initiation(GO:0075522) protein localization to cytoplasmic stress granule(GO:1903608)
0.1 2.1 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 2.2 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 8.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 0.8 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 0.2 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 2.7 GO:0019915 lipid storage(GO:0019915)
0.1 0.2 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 2.8 GO:0003341 cilium movement(GO:0003341)
0.1 6.8 GO:0007605 sensory perception of sound(GO:0007605)
0.1 2.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.2 GO:0070488 neutrophil aggregation(GO:0070488)
0.1 0.5 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.5 GO:0050878 regulation of body fluid levels(GO:0050878)
0.0 10.9 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.1 GO:0031424 keratinization(GO:0031424)
0.0 1.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.8 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 1.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.3 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 2.7 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.9 GO:0016064 immunoglobulin mediated immune response(GO:0016064)
0.0 0.0 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.2 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.3 GO:0016571 histone methylation(GO:0016571)
0.0 0.5 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 2.0 GO:0051607 defense response to virus(GO:0051607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 48.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
5.9 17.8 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
5.8 17.5 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
5.4 21.5 GO:0097450 astrocyte end-foot(GO:0097450)
5.3 15.8 GO:0071953 elastic fiber(GO:0071953)
3.8 15.1 GO:0045098 type III intermediate filament(GO:0045098)
3.2 28.6 GO:0097449 astrocyte projection(GO:0097449)
2.7 10.7 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
2.1 32.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.1 12.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
2.0 5.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.8 7.2 GO:0043259 laminin-10 complex(GO:0043259)
1.3 3.8 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
1.1 14.4 GO:0070852 cell body fiber(GO:0070852)
1.1 8.5 GO:0033269 internode region of axon(GO:0033269)
1.0 9.2 GO:0008278 cohesin complex(GO:0008278)
1.0 8.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.0 10.6 GO:0005915 zonula adherens(GO:0005915)
0.9 2.8 GO:0036156 inner dynein arm(GO:0036156)
0.9 4.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 3.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.7 4.6 GO:0042825 TAP complex(GO:0042825)
0.5 13.4 GO:0002102 podosome(GO:0002102)
0.5 4.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.5 2.7 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.4 11.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 5.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 2.0 GO:0005861 troponin complex(GO:0005861)
0.4 8.3 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.4 8.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.4 27.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 24.1 GO:0005581 collagen trimer(GO:0005581)
0.3 24.2 GO:0005604 basement membrane(GO:0005604)
0.3 2.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.3 3.9 GO:0031045 dense core granule(GO:0031045)
0.3 50.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 9.2 GO:0031902 late endosome membrane(GO:0031902)
0.2 7.9 GO:0030673 axolemma(GO:0030673)
0.2 3.4 GO:0032433 filopodium tip(GO:0032433)
0.2 6.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.2 3.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 6.7 GO:0097440 apical dendrite(GO:0097440)
0.2 8.8 GO:0044297 cell body(GO:0044297)
0.2 12.0 GO:0005844 polysome(GO:0005844)
0.2 7.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 2.0 GO:0001527 microfibril(GO:0001527)
0.2 18.6 GO:0005814 centriole(GO:0005814)
0.2 18.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 1.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 8.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.2 8.8 GO:0005811 lipid particle(GO:0005811)
0.1 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.6 GO:0001741 XY body(GO:0001741)
0.1 46.0 GO:0043025 neuronal cell body(GO:0043025)
0.1 9.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 19.3 GO:0042383 sarcolemma(GO:0042383)
0.1 5.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 5.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 110.7 GO:0005615 extracellular space(GO:0005615)
0.1 2.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 4.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 43.1 GO:0030424 axon(GO:0030424)
0.1 5.4 GO:0072686 mitotic spindle(GO:0072686)
0.1 3.3 GO:0005901 caveola(GO:0005901)
0.1 25.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 3.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.2 GO:0005938 cell cortex(GO:0005938)
0.0 5.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0001533 cornified envelope(GO:0001533)
0.0 24.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 5.7 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 37.1 GO:0016021 integral component of membrane(GO:0016021)
0.0 2.2 GO:0016023 cytoplasmic, membrane-bounded vesicle(GO:0016023)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
12.9 77.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
9.1 36.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
6.4 32.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
6.1 18.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
5.1 20.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
5.1 30.5 GO:0015265 urea channel activity(GO:0015265)
4.7 23.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
4.5 17.8 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
4.0 52.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
3.8 15.1 GO:1990254 keratin filament binding(GO:1990254)
3.4 13.4 GO:0008131 primary amine oxidase activity(GO:0008131)
3.0 9.1 GO:0035939 microsatellite binding(GO:0035939)
2.9 8.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
2.9 11.6 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
2.9 8.7 GO:0003884 D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922)
2.8 41.7 GO:0008430 selenium binding(GO:0008430)
2.7 10.9 GO:0030156 benzodiazepine receptor binding(GO:0030156)
2.2 8.8 GO:0004074 biliverdin reductase activity(GO:0004074)
2.2 2.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.1 8.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.1 48.6 GO:0051787 misfolded protein binding(GO:0051787)
2.0 10.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
2.0 18.1 GO:0015643 toxic substance binding(GO:0015643)
2.0 7.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
2.0 7.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.9 11.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.8 10.9 GO:0019841 retinol binding(GO:0019841)
1.8 5.3 GO:0008521 acetyl-CoA transporter activity(GO:0008521)
1.7 66.1 GO:0005504 fatty acid binding(GO:0005504)
1.6 12.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.5 12.2 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
1.5 10.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.4 19.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.3 7.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
1.3 3.8 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
1.2 10.9 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
1.1 4.6 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
1.1 26.8 GO:0030506 ankyrin binding(GO:0030506)
1.1 3.2 GO:0005534 galactose binding(GO:0005534)
0.9 5.7 GO:0009374 biotin binding(GO:0009374)
0.9 5.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.9 10.6 GO:0070097 delta-catenin binding(GO:0070097)
0.8 11.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.8 9.2 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.8 9.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.7 5.9 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.7 2.9 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.7 2.0 GO:0030172 troponin C binding(GO:0030172)
0.7 3.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.6 5.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.6 6.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.6 1.8 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.6 3.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.6 4.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.6 60.6 GO:0005178 integrin binding(GO:0005178)
0.5 4.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 4.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.5 1.5 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.5 13.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 6.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 1.8 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.4 5.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 17.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.4 6.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 13.7 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.4 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 8.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 6.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 2.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.3 11.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 1.3 GO:0016675 oxidoreductase activity, acting on a heme group of donors(GO:0016675)
0.3 2.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 8.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 3.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 23.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 15.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 8.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 1.4 GO:0001849 complement component C1q binding(GO:0001849)
0.2 9.2 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.2 0.7 GO:0005118 sevenless binding(GO:0005118)
0.2 1.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 3.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 11.7 GO:0019003 GDP binding(GO:0019003)
0.2 4.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.2 0.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 4.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 2.8 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 3.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 9.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 4.1 GO:0004697 protein kinase C activity(GO:0004697)
0.1 3.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 7.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 4.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 2.7 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.3 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368)
0.1 0.3 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 10.6 GO:0015293 symporter activity(GO:0015293)
0.1 0.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 3.9 GO:0020037 heme binding(GO:0020037)
0.1 5.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 2.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 3.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.2 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 7.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 1.8 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042281)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 3.7 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.5 GO:0003729 mRNA binding(GO:0003729)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)