Motif ID: Nfkb2

Z-value: 0.536


Transcription factors associated with Nfkb2:

Gene SymbolEntrez IDGene Name
Nfkb2 ENSMUSG00000025225.8 Nfkb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfkb2mm10_v2_chr19_+_46305682_46305741-0.291.5e-02Click!


Activity profile for motif Nfkb2.

activity profile for motif Nfkb2


Sorted Z-values histogram for motif Nfkb2

Sorted Z-values for motif Nfkb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfkb2

PNG image of the network

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Top targets:


Showing 1 to 20 of 73 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_29289300 4.729 ENSMUST00000048187.4
Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr1_+_74791516 4.631 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr19_+_7268296 3.181 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chrX_+_163908982 2.582 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr1_+_167001417 2.420 ENSMUST00000165874.1
Fam78b
family with sequence similarity 78, member B
chr13_-_111490111 2.335 ENSMUST00000047627.7
Gpbp1
GC-rich promoter binding protein 1
chr2_-_37422869 2.181 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr13_-_111490028 2.160 ENSMUST00000091236.4
Gpbp1
GC-rich promoter binding protein 1
chr2_+_172550991 2.081 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chrX_+_163909132 1.973 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr2_+_172550761 1.940 ENSMUST00000099058.3
Tfap2c
transcription factor AP-2, gamma
chr1_+_153740344 1.658 ENSMUST00000027748.7
Rgs16
regulator of G-protein signaling 16
chr14_-_30607808 1.593 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
Prkcd



protein kinase C, delta



chr1_+_167001457 1.492 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr1_-_66817536 1.463 ENSMUST00000068168.3
ENSMUST00000113987.1
Kansl1l

KAT8 regulatory NSL complex subunit 1-like

chr11_+_101176041 1.404 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chr11_-_54962903 1.355 ENSMUST00000108885.1
ENSMUST00000102730.2
ENSMUST00000018482.6
ENSMUST00000108886.1
ENSMUST00000102731.1
Tnip1




TNFAIP3 interacting protein 1




chr14_-_30626196 1.271 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd


protein kinase C, delta


chr4_-_125127817 1.266 ENSMUST00000036188.7
Zc3h12a
zinc finger CCCH type containing 12A
chr5_+_37245792 1.176 ENSMUST00000031004.7
Crmp1
collapsin response mediator protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 4.8 GO:0035690 cellular response to drug(GO:0035690)
0.5 4.6 GO:0048733 sebaceous gland development(GO:0048733)
1.3 4.0 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.6 2.9 GO:0006680 glucosylceramide catabolic process(GO:0006680) negative regulation of filopodium assembly(GO:0051490)
0.2 2.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.3 2.0 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.4 1.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.4 1.3 GO:0045472 response to ether(GO:0045472) negative regulation of interleukin-1 beta secretion(GO:0050713) negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of tumor necrosis factor secretion(GO:1904468)
0.3 1.2 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.3 1.1 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943)
0.0 0.9 GO:0060384 innervation(GO:0060384)
0.0 0.8 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.6 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.5 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 1.4 GO:0033270 paranode region of axon(GO:0033270)
0.3 1.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.8 GO:0042581 specific granule(GO:0042581)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 4.6 GO:0005109 frizzled binding(GO:0005109)
0.0 4.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.0 GO:0008565 protein transporter activity(GO:0008565)
0.7 2.9 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.0 2.2 GO:0003729 mRNA binding(GO:0003729)
0.0 2.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.2 GO:0031005 filamin binding(GO:0031005)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0045296 cadherin binding(GO:0045296)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)