Motif ID: Nkx2-3
Z-value: 0.843

Transcription factors associated with Nkx2-3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nkx2-3 | ENSMUSG00000044220.12 | Nkx2-3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nkx2-3 | mm10_v2_chr19_+_43612299_43612325 | 0.41 | 5.0e-04 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 117 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 43.7 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.1 | 7.1 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.6 | 6.6 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
2.1 | 6.4 | GO:0060166 | olfactory pit development(GO:0060166) |
1.4 | 5.7 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.0 | 5.6 | GO:0030326 | embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113) |
0.1 | 5.3 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
0.3 | 5.2 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.6 | 4.9 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 4.7 | GO:0007601 | visual perception(GO:0007601) |
0.6 | 4.4 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.1 | 4.0 | GO:0021954 | central nervous system neuron development(GO:0021954) |
0.2 | 3.8 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
0.7 | 3.7 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
1.2 | 3.6 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
0.1 | 3.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.5 | 3.0 | GO:0060539 | diaphragm development(GO:0060539) |
0.3 | 3.0 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.4 | 2.6 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.4 | 2.6 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 53 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 7.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 6.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.2 | 5.7 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 4.8 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.5 | 4.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.0 | 4.6 | GO:0005815 | microtubule organizing center(GO:0005815) |
0.0 | 4.3 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.3 | 4.2 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 3.6 | GO:0043034 | costamere(GO:0043034) |
0.8 | 2.4 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
0.3 | 2.4 | GO:0005818 | aster(GO:0005818) |
0.8 | 2.3 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
0.3 | 2.3 | GO:0001940 | male pronucleus(GO:0001940) |
0.0 | 2.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.4 | 2.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 2.2 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 1.9 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.2 | 1.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.3 | 1.4 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.2 | 1.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 71 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 38.3 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.2 | 7.1 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.8 | 5.7 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.2 | 5.3 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.2 | 5.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 5.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.3 | 5.1 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.4 | 4.9 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.6 | 4.6 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 4.6 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 4.5 | GO:0051015 | actin filament binding(GO:0051015) |
0.6 | 4.4 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.0 | 3.8 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
0.5 | 3.6 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 3.2 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.6 | 3.0 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.0 | 2.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.8 | 2.4 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
0.5 | 2.4 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.5 | 2.3 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132) |