Motif ID: Nr0b1

Z-value: 0.654


Transcription factors associated with Nr0b1:

Gene SymbolEntrez IDGene Name
Nr0b1 ENSMUSG00000025056.4 Nr0b1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_86191782-0.104.1e-01Click!


Activity profile for motif Nr0b1.

activity profile for motif Nr0b1


Sorted Z-values histogram for motif Nr0b1

Sorted Z-values for motif Nr0b1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr0b1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_19094594 6.314 ENSMUST00000049454.5
Six5
sine oculis-related homeobox 5
chr16_-_45844228 4.342 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844303 4.341 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr11_+_102604370 3.792 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr7_+_79500081 3.779 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr7_+_79500018 3.710 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr17_-_70851189 3.670 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr1_-_9700209 3.567 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr9_+_80165079 3.396 ENSMUST00000184480.1
Myo6
myosin VI
chr9_+_80165013 2.934 ENSMUST00000035889.8
ENSMUST00000113268.1
Myo6

myosin VI

chr5_-_99037035 2.685 ENSMUST00000031277.6
Prkg2
protein kinase, cGMP-dependent, type II
chr1_+_42697146 2.559 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr13_-_29984219 2.540 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr5_+_64803513 2.516 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr11_+_94328242 2.460 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr5_-_99037342 2.383 ENSMUST00000161490.1
Prkg2
protein kinase, cGMP-dependent, type II
chr10_-_81350389 2.237 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr14_+_11553523 2.206 ENSMUST00000022264.6
Ptprg
protein tyrosine phosphatase, receptor type, G
chr18_+_35829798 2.196 ENSMUST00000060722.6
Cxxc5
CXXC finger 5
chr11_+_94327984 2.118 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr4_-_132422484 1.629 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chrX_-_145505175 1.584 ENSMUST00000143610.1
Amot
angiomotin
chr5_+_30913398 1.548 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr4_-_132422394 1.450 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr19_-_46039442 1.445 ENSMUST00000137771.1
Ldb1
LIM domain binding 1
chr8_-_105707933 1.440 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr7_-_65371210 1.382 ENSMUST00000102592.3
Tjp1
tight junction protein 1
chr5_-_115436508 1.326 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr3_+_86224665 1.311 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chrX_-_48034842 1.302 ENSMUST00000039026.7
Apln
apelin
chr2_-_54085542 1.269 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr4_-_123750236 1.254 ENSMUST00000102636.3
Akirin1
akirin 1
chr4_+_148130883 1.150 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr7_+_82867327 1.010 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr2_+_30066419 0.964 ENSMUST00000067996.6
Set
SET nuclear oncogene
chr17_+_29490812 0.958 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr2_+_71786923 0.942 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr2_+_4718145 0.886 ENSMUST00000056914.6
Bend7
BEN domain containing 7
chr11_-_74723829 0.844 ENSMUST00000102520.2
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr14_+_75845296 0.733 ENSMUST00000142061.1
Tpt1
tumor protein, translationally-controlled 1
chr7_+_28180226 0.697 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr19_+_45015198 0.694 ENSMUST00000179108.1
Lzts2
leucine zipper, putative tumor suppressor 2
chr10_-_127666673 0.664 ENSMUST00000026469.2
Nab2
Ngfi-A binding protein 2
chr15_-_38078842 0.560 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr8_-_95434869 0.550 ENSMUST00000034249.6
Gtl3
gene trap locus 3
chr10_-_128589650 0.491 ENSMUST00000082059.6
Erbb3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr4_-_138913915 0.471 ENSMUST00000097830.3
Otud3
OTU domain containing 3
chr13_-_64274879 0.457 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr2_+_157279026 0.454 ENSMUST00000116380.2
Rpn2
ribophorin II
chr7_+_28180272 0.451 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr17_+_34898463 0.445 ENSMUST00000114033.2
ENSMUST00000078061.6
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr5_+_110230975 0.433 ENSMUST00000031474.7
ENSMUST00000086674.5
Ankle2

ankyrin repeat and LEM domain containing 2

chr18_+_80046854 0.422 ENSMUST00000070219.7
Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr17_-_23745829 0.377 ENSMUST00000046525.8
Kremen2
kringle containing transmembrane protein 2
chr13_-_94358818 0.344 ENSMUST00000059598.2
Gm9776
predicted gene 9776
chr2_+_157279065 0.333 ENSMUST00000029171.5
Rpn2
ribophorin II
chr11_+_105181793 0.325 ENSMUST00000092537.3
ENSMUST00000015107.6
ENSMUST00000145048.1
Tlk2


tousled-like kinase 2 (Arabidopsis)


chr6_+_47454320 0.319 ENSMUST00000031697.8
Cul1
cullin 1
chr11_-_70687917 0.307 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr11_+_50237002 0.268 ENSMUST00000180443.1
Gm26542
predicted gene, 26542
chr2_+_85037448 0.239 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr11_+_77930800 0.224 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr5_+_31193227 0.207 ENSMUST00000031029.8
ENSMUST00000133711.1
ENSMUST00000132471.1
Snx17


sorting nexin 17


chr13_-_106936907 0.194 ENSMUST00000080856.7
Ipo11
importin 11
chr2_-_65238625 0.167 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobll1


Cobl-like 1


chr5_+_121711609 0.159 ENSMUST00000051950.7
Atxn2
ataxin 2
chr11_+_23306884 0.110 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr17_-_80728026 0.109 ENSMUST00000112389.2
ENSMUST00000025089.7
Map4k3

mitogen-activated protein kinase kinase kinase kinase 3

chr11_+_105181527 0.104 ENSMUST00000106941.2
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr11_+_107547925 0.103 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr3_-_86920830 0.095 ENSMUST00000029719.8
Dclk2
doublecortin-like kinase 2
chr4_-_135971894 0.092 ENSMUST00000105852.1
Lypla2
lysophospholipase 2
chr8_-_85080679 0.089 ENSMUST00000093357.5
Wdr83
WD repeat domain containing 83

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.9 2.6 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.8 3.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.8 3.8 GO:0007223 muscular septum morphogenesis(GO:0003150) Wnt signaling pathway, calcium modulating pathway(GO:0007223) hard palate development(GO:0060022)
0.5 6.3 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.5 2.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.5 6.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.5 5.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.4 1.6 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.4 1.4 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 1.0 GO:0072697 protein localization to cell cortex(GO:0072697)
0.3 1.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 0.8 GO:0051660 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
0.2 0.9 GO:0035878 nail development(GO:0035878)
0.2 3.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.6 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.2 1.3 GO:0051461 positive regulation of heat generation(GO:0031652) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 0.7 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.4 GO:0036166 phenotypic switching(GO:0036166)
0.1 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 2.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.7 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 2.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.3 GO:0016197 endosomal transport(GO:0016197)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 1.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.7 GO:0045180 basal cortex(GO:0045180)
0.6 2.2 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.3 6.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.2 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.8 GO:0000235 astral microtubule(GO:0000235)
0.1 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.7 GO:0045298 tubulin complex(GO:0045298)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 6.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 2.3 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
1.0 3.1 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.5 1.6 GO:0043532 angiostatin binding(GO:0043532)
0.5 3.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 1.4 GO:0038132 neuregulin binding(GO:0038132)
0.2 4.8 GO:0008432 JUN kinase binding(GO:0008432)
0.2 3.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 2.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 6.3 GO:0003774 motor activity(GO:0003774)
0.0 1.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 4.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.3 GO:0001047 core promoter binding(GO:0001047)