Motif ID: Nr1i3

Z-value: 1.648


Transcription factors associated with Nr1i3:

Gene SymbolEntrez IDGene Name
Nr1i3 ENSMUSG00000005677.8 Nr1i3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1i3mm10_v2_chr1_+_171213969_171214007-0.353.4e-03Click!


Activity profile for motif Nr1i3.

activity profile for motif Nr1i3


Sorted Z-values histogram for motif Nr1i3

Sorted Z-values for motif Nr1i3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1i3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_166254095 20.233 ENSMUST00000111416.1
 Ildr2
immunoglobulin-like domain containing receptor 2
chr4_-_137785371 18.719 ENSMUST00000133473.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr1_+_90203980 18.256 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr9_-_54661870 15.287 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr1_-_163289214 14.308 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1
chr9_-_54661666 14.280 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_+_32276400 13.548 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr7_-_115846080 13.450 ENSMUST00000166207.1
 Sox6
SRY-box containing gene 6
chr9_+_65630552 13.410 ENSMUST00000055844.8
 Rbpms2
RNA binding protein with multiple splicing 2
chr1_+_135729147 13.389 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr16_+_30065333 13.081 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chr4_-_148087961 12.655 ENSMUST00000030865.8
 Agtrap
angiotensin II, type I receptor-associated protein
chr14_+_46882854 12.652 ENSMUST00000022386.8
ENSMUST00000100672.3
 Samd4

sterile alpha motif domain containing 4

chr5_-_116422858 12.430 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr11_-_3931960 11.921 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
 Tcn2




transcobalamin 2




chr16_+_91269759 11.848 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr2_+_118813995 11.553 ENSMUST00000134661.1
 Knstrn
kinetochore-localized astrin/SPAG5 binding
chr17_+_47505117 11.161 ENSMUST00000183044.1
ENSMUST00000037333.10
 Ccnd3

cyclin D3

chr14_-_48667508 11.100 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr1_-_120120138 11.043 ENSMUST00000112648.1
ENSMUST00000128408.1
 Dbi

diazepam binding inhibitor


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 652 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 39.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
2.2 37.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.0 35.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.6 31.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.3 26.2 GO:0045727 positive regulation of translation(GO:0045727)
0.5 24.5 GO:0070206 protein trimerization(GO:0070206)
7.7 23.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.8 23.1 GO:0046677 response to antibiotic(GO:0046677)
2.0 22.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.2 21.1 GO:0030903 notochord development(GO:0030903)
4.1 20.4 GO:0015671 oxygen transport(GO:0015671)
4.1 20.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.7 18.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
3.0 17.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
5.8 17.5 GO:0015889 cobalamin transport(GO:0015889)
0.9 17.3 GO:0038092 nodal signaling pathway(GO:0038092)
5.6 16.9 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.5 16.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
1.1 16.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
2.0 15.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 252 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 106.2 GO:0005667 transcription factor complex(GO:0005667)
0.2 73.7 GO:0005740 mitochondrial envelope(GO:0005740)
0.3 52.3 GO:0031012 extracellular matrix(GO:0031012)
0.2 43.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.9 42.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 41.2 GO:1903561 extracellular organelle(GO:0043230) extracellular vesicle(GO:1903561)
0.4 36.5 GO:0000922 spindle pole(GO:0000922)
0.1 35.9 GO:0005730 nucleolus(GO:0005730)
0.5 33.6 GO:0005657 replication fork(GO:0005657)
0.1 31.8 GO:0005925 focal adhesion(GO:0005925)
0.5 31.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 31.0 GO:0005840 ribosome(GO:0005840)
0.9 28.4 GO:0035371 microtubule plus-end(GO:0035371)
1.6 26.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
3.8 23.1 GO:0061689 tricellular tight junction(GO:0061689)
0.3 21.2 GO:0005604 basement membrane(GO:0005604)
2.5 20.4 GO:0005833 hemoglobin complex(GO:0005833)
1.1 17.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 17.3 GO:0005901 caveola(GO:0005901)
0.4 17.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 421 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 38.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
1.0 33.5 GO:0071837 HMG box domain binding(GO:0071837)
0.4 31.9 GO:0005178 integrin binding(GO:0005178)
0.7 31.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
2.8 30.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.0 27.5 GO:0030371 translation repressor activity(GO:0030371)
0.1 26.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
6.4 25.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
4.2 25.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.3 23.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 22.7 GO:0003735 structural constituent of ribosome(GO:0003735)
1.1 22.0 GO:0017049 GTP-Rho binding(GO:0017049)
6.8 20.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
5.1 20.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
4.1 20.4 GO:0005344 oxygen transporter activity(GO:0005344)
1.3 19.8 GO:0008430 selenium binding(GO:0008430)
3.6 18.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
2.6 18.2 GO:0031419 cobalamin binding(GO:0031419)
1.2 17.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.7 17.4 GO:0008432 JUN kinase binding(GO:0008432)