Motif ID: Nr2e1

Z-value: 0.373


Transcription factors associated with Nr2e1:

Gene SymbolEntrez IDGene Name
Nr2e1 ENSMUSG00000019803.5 Nr2e1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2e1mm10_v2_chr10_-_42583628_42583639-0.598.0e-08Click!


Activity profile for motif Nr2e1.

activity profile for motif Nr2e1


Sorted Z-values histogram for motif Nr2e1

Sorted Z-values for motif Nr2e1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_33924632 4.698 ENSMUST00000057188.6
 Cnr1
cannabinoid receptor 1 (brain)
chr3_+_26331150 2.162 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene
chr14_+_32028989 1.528 ENSMUST00000022460.4
 Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr2_-_73386396 1.411 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
 Gpr155


G protein-coupled receptor 155


chr1_-_132390301 1.243 ENSMUST00000132435.1
 Tmcc2
transmembrane and coiled-coil domains 2
chrX_-_95658379 1.213 ENSMUST00000119640.1
 Zc4h2
zinc finger, C4H2 domain containing
chr3_-_146781351 1.105 ENSMUST00000005164.7
 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr4_+_32238950 1.079 ENSMUST00000037416.6
 Bach2
BTB and CNC homology 2
chr18_+_34840575 1.063 ENSMUST00000043484.7
 Reep2
receptor accessory protein 2
chrX_-_95658392 1.056 ENSMUST00000120620.1
 Zc4h2
zinc finger, C4H2 domain containing
chr8_+_36489191 1.014 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chrX_-_95658416 0.989 ENSMUST00000044382.6
 Zc4h2
zinc finger, C4H2 domain containing
chr4_-_35845204 0.968 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr9_-_58158498 0.897 ENSMUST00000168864.2
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr4_+_28813125 0.875 ENSMUST00000029964.5
ENSMUST00000080934.4
 Epha7

Eph receptor A7

chr7_+_114768736 0.862 ENSMUST00000117543.1
 Insc
inscuteable homolog (Drosophila)
chr10_+_18469958 0.802 ENSMUST00000162891.1
ENSMUST00000100054.3
 Nhsl1

NHS-like 1

chr4_+_28813152 0.742 ENSMUST00000108194.2
ENSMUST00000108191.1
 Epha7

Eph receptor A7

chrX_-_139998519 0.647 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
 Rbm41



RNA binding motif protein 41



chr2_-_23040137 0.539 ENSMUST00000091394.6
ENSMUST00000093171.6
 Abi1

abl-interactor 1

chr2_-_23040177 0.523 ENSMUST00000114544.3
ENSMUST00000139038.1
ENSMUST00000126112.1
ENSMUST00000178908.1
ENSMUST00000078977.7
ENSMUST00000140164.1
ENSMUST00000149719.1
 Abi1






abl-interactor 1






chr6_+_126939957 0.505 ENSMUST00000032497.3
 D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chr2_-_23040092 0.435 ENSMUST00000153931.1
ENSMUST00000123948.1
 Abi1

abl-interactor 1

chr4_-_119415494 0.429 ENSMUST00000063642.2
 Ccdc30
coiled-coil domain containing 30
chr7_+_78895903 0.394 ENSMUST00000107425.1
ENSMUST00000107421.1
ENSMUST00000107423.1
 Aen


apoptosis enhancing nuclease


chr15_+_41830921 0.376 ENSMUST00000166917.1
 Oxr1
oxidation resistance 1
chr9_-_42457594 0.175 ENSMUST00000125995.1
 Tbcel
tubulin folding cofactor E-like
chr15_-_97705787 0.075 ENSMUST00000023104.5
 Rpap3
RNA polymerase II associated protein 3
chr17_+_33919332 0.064 ENSMUST00000025161.7
 Tapbp
TAP binding protein
chr1_+_24678536 0.048 ENSMUST00000095062.3
 Lmbrd1
LMBR1 domain containing 1
chr5_-_88527841 0.038 ENSMUST00000087033.3
 Igj
immunoglobulin joining chain
chr4_+_136347286 0.034 ENSMUST00000140052.2
 9130020K20Rik
RIKEN cDNA 9130020K20 gene
chrM_+_7005 0.013 ENSMUST00000082405.1
 mt-Co2
mitochondrially encoded cytochrome c oxidase II

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0031622 positive regulation of fever generation(GO:0031622)
0.3 1.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.3 1.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 1.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 1.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.9 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.5 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.3 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 3.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 4.7 GO:0008144 drug binding(GO:0008144)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)