Motif ID: Nr2f2

Z-value: 0.613


Transcription factors associated with Nr2f2:

Gene SymbolEntrez IDGene Name
Nr2f2 ENSMUSG00000030551.7 Nr2f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f2mm10_v2_chr7_-_70360593_70360746-0.467.3e-05Click!


Activity profile for motif Nr2f2.

activity profile for motif Nr2f2


Sorted Z-values histogram for motif Nr2f2

Sorted Z-values for motif Nr2f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_92278155 3.126 ENSMUST00000159345.1
ENSMUST00000113102.3
 Naaa

N-acylethanolamine acid amidase

chr13_-_34652671 3.122 ENSMUST00000053459.7
 Pxdc1
PX domain containing 1
chr11_-_98053415 3.029 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr3_+_121723515 2.683 ENSMUST00000029771.8
 F3
coagulation factor III
chr12_+_81026800 2.123 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
 Smoc1


SPARC related modular calcium binding 1


chr4_-_137766474 2.045 ENSMUST00000139951.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr5_+_64803513 1.965 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr9_-_54661870 1.959 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr15_-_37791993 1.935 ENSMUST00000168992.1
ENSMUST00000148652.1
 Ncald

neurocalcin delta

chr5_-_71658308 1.929 ENSMUST00000031121.5
 Gabra4
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr17_-_12507704 1.929 ENSMUST00000024595.2
 Slc22a3
solute carrier family 22 (organic cation transporter), member 3
chr1_+_9547948 1.741 ENSMUST00000144177.1
 Adhfe1
alcohol dehydrogenase, iron containing, 1
chr13_-_96132568 1.732 ENSMUST00000161263.1
 Sv2c
synaptic vesicle glycoprotein 2c
chr15_-_78529617 1.720 ENSMUST00000023075.8
 C1qtnf6
C1q and tumor necrosis factor related protein 6
chr3_+_83766300 1.711 ENSMUST00000029625.7
 Sfrp2
secreted frizzled-related protein 2
chr9_-_54661666 1.706 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr10_-_9675163 1.655 ENSMUST00000100070.2
 Samd5
sterile alpha motif domain containing 5
chr3_-_116712198 1.637 ENSMUST00000120120.1
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr6_-_134632388 1.615 ENSMUST00000047443.3
 Mansc1
MANSC domain containing 1
chr3_-_132950043 1.430 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
 Npnt




nephronectin





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.8 4.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.3 3.3 GO:0051608 histamine transport(GO:0051608)
0.1 2.7 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.1 2.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 2.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 2.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 2.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 2.0 GO:0046677 response to antibiotic(GO:0046677)
0.3 1.9 GO:2001023 regulation of response to drug(GO:2001023)
0.0 1.9 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.6 1.7 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.6 1.7 GO:1904956 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 1.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 1.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 1.7 GO:0006818 hydrogen transport(GO:0006818)
0.5 1.6 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.4 1.4 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.3 1.4 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 1.4 GO:0035624 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) response to high density lipoprotein particle(GO:0055099)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.6 2.3 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 2.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 2.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 1.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.4 1.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 1.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.2 1.3 GO:0001520 outer dense fiber(GO:0001520)
0.2 1.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.1 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.3 3.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 3.1 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.1 2.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 2.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.8 2.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 2.2 GO:0008201 heparin binding(GO:0008201)
0.1 2.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.5 2.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 2.0 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.6 1.9 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 1.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.6 1.7 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 1.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 1.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 1.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)