Motif ID: Nr2f6

Z-value: 0.709


Transcription factors associated with Nr2f6:

Gene SymbolEntrez IDGene Name
Nr2f6 ENSMUSG00000002393.8 Nr2f6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f6mm10_v2_chr8_-_71381907_71381977-0.414.4e-04Click!


Activity profile for motif Nr2f6.

activity profile for motif Nr2f6


Sorted Z-values histogram for motif Nr2f6

Sorted Z-values for motif Nr2f6



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f6

PNG image of the network

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Top targets:


Showing 1 to 20 of 135 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_85205417 6.808 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
 Sh3gl2


SH3-domain GRB2-like 2


chr4_+_85205120 6.539 ENSMUST00000107188.3
 Sh3gl2
SH3-domain GRB2-like 2
chr5_-_137741601 5.644 ENSMUST00000119498.1
ENSMUST00000061789.7
 Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr15_+_89532816 5.377 ENSMUST00000167173.1
 Shank3
SH3/ankyrin domain gene 3
chr8_+_71469186 5.334 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
 Dda1


DET1 and DDB1 associated 1


chr17_-_35910032 4.616 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
 Atat1




alpha tubulin acetyltransferase 1




chr3_+_121967822 4.504 ENSMUST00000137089.1
 Arhgap29
Rho GTPase activating protein 29
chr7_+_45896941 4.219 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr9_+_109051153 3.583 ENSMUST00000155541.1
ENSMUST00000120305.1
ENSMUST00000154113.1
ENSMUST00000128976.1
ENSMUST00000135942.1
ENSMUST00000143754.1
 Shisa5





shisa homolog 5 (Xenopus laevis)





chr17_-_35909626 3.539 ENSMUST00000141132.1
 Atat1
alpha tubulin acetyltransferase 1
chr16_-_4624984 3.211 ENSMUST00000014445.6
 Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr7_-_30232186 3.137 ENSMUST00000006254.5
 Tbcb
tubulin folding cofactor B
chr15_-_95528702 3.089 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr7_-_28766469 3.068 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr7_+_45897429 2.852 ENSMUST00000140243.1
 Tmem143
transmembrane protein 143
chr19_+_47228804 2.831 ENSMUST00000111807.3
 Neurl1a
neuralized homolog 1A (Drosophila)
chr10_-_79983970 2.830 ENSMUST00000124536.1
 Tmem259
transmembrane protein 259
chr5_+_117120120 2.703 ENSMUST00000111978.1
 Taok3
TAO kinase 3
chr9_+_108392820 2.653 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr11_+_32283511 2.584 ENSMUST00000093209.3
 Hba-a1
hemoglobin alpha, adult chain 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 13.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 9.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
2.7 8.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 5.6 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
1.1 5.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.3 5.4 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 4.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 4.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 3.6 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 3.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.5 3.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.3 3.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.4 2.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 2.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.6 GO:0048821 erythrocyte development(GO:0048821)
0.1 2.5 GO:0034340 response to type I interferon(GO:0034340)
0.1 2.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 2.3 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.1 2.2 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 2.2 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 8.2 GO:0097427 microtubule bundle(GO:0097427)
0.1 5.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 4.0 GO:0008021 synaptic vesicle(GO:0008021)
0.5 3.2 GO:0031314 mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 3.1 GO:0043204 perikaryon(GO:0043204)
0.1 2.8 GO:0097440 apical dendrite(GO:0097440)
0.6 2.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.8 2.3 GO:1990879 CST complex(GO:1990879)
0.1 2.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 1.6 GO:0070826 paraferritin complex(GO:0070826)
0.3 1.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 1.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.1 1.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.3 GO:0008289 lipid binding(GO:0008289)
0.1 5.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
1.3 5.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 4.5 GO:0005496 steroid binding(GO:0005496)
0.1 3.9 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 3.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.6 GO:0050699 WW domain binding(GO:0050699)
0.0 3.3 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 3.1 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.8 GO:0045182 translation regulator activity(GO:0045182)
0.6 2.6 GO:0031720 haptoglobin binding(GO:0031720)
0.1 2.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 2.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 2.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 2.2 GO:0070403 NAD+ binding(GO:0070403)
0.1 2.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 2.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.8 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.7 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)