Motif ID: Nr2f6
Z-value: 0.709
Transcription factors associated with Nr2f6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nr2f6 | ENSMUSG00000002393.8 | Nr2f6 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nr2f6 | mm10_v2_chr8_-_71381907_71381977 | -0.41 | 4.4e-04 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.2 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 1.1 | 5.4 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.6 | 1.7 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.5 | 3.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.5 | 1.5 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.5 | 1.5 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
| 0.5 | 0.9 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.4 | 2.8 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.4 | 1.6 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 0.4 | 13.3 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.3 | 1.4 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.3 | 5.4 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.3 | 1.6 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
| 0.3 | 3.1 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.3 | 4.0 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.3 | 1.4 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.3 | 1.1 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.2 | 1.7 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.2 | 1.0 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.2 | 0.6 | GO:0071105 | response to interleukin-11(GO:0071105) osteoclast fusion(GO:0072675) |
| 0.2 | 1.7 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 2.7 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 2.2 | GO:0010566 | regulation of ketone biosynthetic process(GO:0010566) |
| 0.1 | 0.4 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 2.3 | GO:0051974 | negative regulation of telomerase activity(GO:0051974) |
| 0.1 | 3.6 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.1 | 1.9 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 1.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 2.5 | GO:0034340 | response to type I interferon(GO:0034340) |
| 0.1 | 0.8 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 2.2 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.1 | 0.6 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.1 | 1.1 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 1.7 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 0.2 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
| 0.1 | 3.6 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.1 | 0.4 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.1 | 4.4 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 0.2 | GO:0050748 | negative regulation of lipoprotein metabolic process(GO:0050748) |
| 0.1 | 2.6 | GO:0048821 | erythrocyte development(GO:0048821) |
| 0.1 | 2.4 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 0.2 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.1 | 9.1 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.1 | 5.6 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
| 0.0 | 1.6 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.0 | 1.0 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.0 | 0.4 | GO:0043649 | dicarboxylic acid catabolic process(GO:0043649) |
| 0.0 | 1.4 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 0.3 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.0 | 0.6 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.9 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 0.4 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.0 | 0.5 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 8.2 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.8 | 2.3 | GO:1990879 | CST complex(GO:1990879) |
| 0.6 | 2.6 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.5 | 3.2 | GO:0031314 | mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.3 | 1.6 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.3 | 1.6 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.2 | 0.2 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.2 | 1.6 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.2 | 0.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 0.8 | GO:0002139 | stereocilia coupling link(GO:0002139) |
| 0.1 | 2.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 0.6 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
| 0.1 | 5.6 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.1 | 0.7 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 1.5 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 1.3 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.1 | 0.2 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 2.8 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 0.4 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 0.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.0 | 1.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.5 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 1.8 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 2.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 3.1 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 4.0 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.3 | GO:0022626 | cytosolic ribosome(GO:0022626) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.4 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.6 | 2.6 | GO:0031720 | haptoglobin binding(GO:0031720) |
| 0.4 | 1.5 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.3 | 1.6 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.2 | 2.3 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.2 | 2.2 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.2 | 1.8 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 2.2 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.1 | 0.8 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 0.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 0.7 | GO:0015288 | porin activity(GO:0015288) |
| 0.1 | 1.4 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.1 | 3.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 3.9 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
| 0.1 | 0.8 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.1 | 2.1 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 5.8 | GO:0061733 | peptide-lysine-N-acetyltransferase activity(GO:0061733) |
| 0.1 | 0.2 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) |
| 0.1 | 0.4 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.1 | 0.5 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
| 0.1 | 0.9 | GO:0004438 | phosphatidylinositol-3-phosphatase activity(GO:0004438) |
| 0.1 | 2.8 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.1 | 1.7 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.1 | 1.3 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 1.1 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.1 | 1.6 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 2.0 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 0.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.8 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 4.5 | GO:0005496 | steroid binding(GO:0005496) |
| 0.1 | 1.7 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.1 | 2.4 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.9 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 3.1 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 3.3 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
| 0.0 | 1.4 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 1.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.3 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.0 | 1.5 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 0.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 1.5 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
| 0.0 | 3.7 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.4 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.0 | 12.3 | GO:0008289 | lipid binding(GO:0008289) |
| 0.0 | 1.6 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.0 | 0.1 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
