Motif ID: Nr3c2

Z-value: 0.732


Transcription factors associated with Nr3c2:

Gene SymbolEntrez IDGene Name
Nr3c2 ENSMUSG00000031618.7 Nr3c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c2mm10_v2_chr8_+_76902277_76902476-0.262.7e-02Click!


Activity profile for motif Nr3c2.

activity profile for motif Nr3c2


Sorted Z-values histogram for motif Nr3c2

Sorted Z-values for motif Nr3c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr3c2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_6882068 16.681 ENSMUST00000142635.1
ENSMUST00000052609.8
 Dlx5

distal-less homeobox 5

chr8_+_94179089 11.551 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr3_-_95904683 9.295 ENSMUST00000147962.1
ENSMUST00000036181.8
 Car14

carbonic anhydrase 14

chr4_-_149137536 7.906 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
 Apitd1



apoptosis-inducing, TAF9-like domain 1



chr8_+_71406003 7.517 ENSMUST00000119976.1
ENSMUST00000120725.1
 Ankle1

ankyrin repeat and LEM domain containing 1

chr9_+_123366921 7.497 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr13_+_99100698 5.234 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr10_+_26822560 4.778 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr14_-_8309770 4.602 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr5_-_31697598 3.743 ENSMUST00000031018.7
 Rbks
ribokinase
chr15_-_97020322 3.618 ENSMUST00000166223.1
 Slc38a4
solute carrier family 38, member 4
chr4_-_9643638 3.515 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr14_+_70530819 3.512 ENSMUST00000047331.6
 Lgi3
leucine-rich repeat LGI family, member 3
chr10_-_78464853 2.669 ENSMUST00000105385.1
 Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr10_-_78464969 2.136 ENSMUST00000041616.8
 Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_-_171240055 1.878 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr3_-_88739692 1.834 ENSMUST00000090946.2
 Gm10253
predicted gene 10253
chr15_+_102102926 1.534 ENSMUST00000169627.1
ENSMUST00000046144.9
 Tenc1

tensin like C1 domain-containing phosphatase

chr2_+_172472512 1.490 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr10_+_128225830 1.136 ENSMUST00000026455.7
 Mip
major intrinsic protein of eye lens fiber
chr16_-_96192222 0.819 ENSMUST00000113804.1
ENSMUST00000054855.7
 Lca5l

Leber congenital amaurosis 5-like

chr5_+_31697665 0.659 ENSMUST00000080598.7
 Bre
brain and reproductive organ-expressed protein
chr1_-_74935549 0.621 ENSMUST00000094844.3
 Ccdc108
coiled-coil domain containing 108
chr6_-_69631933 0.461 ENSMUST00000177697.1
 Igkv4-54
immunoglobulin kappa chain variable 4-54
chr6_-_69400097 0.410 ENSMUST00000177795.1
 Igkv4-62
immunoglobulin kappa variable 4-62
chr10_-_14718191 0.132 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1
chr2_-_91444622 0.120 ENSMUST00000064652.7
ENSMUST00000102594.4
ENSMUST00000094835.2
 1110051M20Rik


RIKEN cDNA 1110051M20 gene



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.7 GO:0060166 olfactory pit development(GO:0060166)
1.7 11.6 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
1.6 4.8 GO:0042822 vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
1.2 3.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.2 9.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.9 7.9 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.5 3.7 GO:0019321 pentose metabolic process(GO:0019321)
0.2 1.1 GO:0032782 cellular water homeostasis(GO:0009992) bile acid secretion(GO:0032782)
0.1 7.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 3.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 4.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 3.5 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.7 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.9 GO:0002377 immunoglobulin production(GO:0002377)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0071821 FANCM-MHF complex(GO:0071821)
0.7 3.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.7 GO:0070552 BRISC complex(GO:0070552)
0.0 1.3 GO:0005921 gap junction(GO:0005921)
0.0 1.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 12.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 3.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 9.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0031403 lithium ion binding(GO:0031403)
0.8 9.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 16.7 GO:0071837 HMG box domain binding(GO:0071837)
0.2 7.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 10.7 GO:0005507 copper ion binding(GO:0005507)
0.2 1.9 GO:0048038 quinone binding(GO:0048038)
0.1 1.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.1 3.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 3.5 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 3.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 7.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)