Motif ID: Nr4a3
Z-value: 0.537
Transcription factors associated with Nr4a3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr4a3 | ENSMUSG00000028341.3 | Nr4a3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr4a3 | mm10_v2_chr4_+_48049080_48049114 | -0.05 | 6.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 6.1 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
0.5 | 3.7 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.4 | 1.2 | GO:0046544 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544) |
0.2 | 0.6 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.2 | 0.8 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
0.1 | 1.0 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.1 | 2.0 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.1 | 0.3 | GO:0086017 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) Purkinje myocyte action potential(GO:0086017) membrane depolarization during SA node cell action potential(GO:0086046) |
0.1 | 0.9 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
0.1 | 1.0 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 0.5 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.1 | 0.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.1 | 0.4 | GO:0006842 | tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) |
0.1 | 0.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.1 | 0.6 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.1 | 0.6 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.1 | 1.4 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
0.1 | 2.2 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.1 | 1.2 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.0 | 0.2 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.0 | 0.5 | GO:0036376 | sodium ion export from cell(GO:0036376) |
0.0 | 1.1 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.6 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
0.0 | 0.1 | GO:0050787 | glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) glyoxal catabolic process(GO:1903190) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) positive regulation of androgen receptor activity(GO:2000825) |
0.0 | 0.3 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
0.0 | 0.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.1 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
0.0 | 0.1 | GO:0033762 | response to glucagon(GO:0033762) |
0.0 | 1.9 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 0.8 | GO:0030865 | cortical cytoskeleton organization(GO:0030865) |
0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.0 | 0.1 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
0.0 | 0.4 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 1.7 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.0 | 0.7 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.0 | 0.4 | GO:0001964 | startle response(GO:0001964) |
0.0 | 0.8 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.8 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.1 | 0.3 | GO:0031983 | vesicle lumen(GO:0031983) |
0.1 | 1.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 1.1 | GO:0030057 | desmosome(GO:0030057) |
0.1 | 0.6 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.1 | 0.6 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.1 | 0.2 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.0 | 0.4 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.6 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.0 | 0.6 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 1.4 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.5 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.3 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.0 | 0.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 1.2 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 0.1 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.0 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
0.0 | 1.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 3.7 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.4 | 1.8 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.3 | 2.0 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.2 | 2.2 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.2 | 1.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.1 | 0.4 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.1 | 0.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 0.6 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.9 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.1 | 0.5 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
0.1 | 0.8 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.1 | 1.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.1 | 0.4 | GO:0015288 | porin activity(GO:0015288) |
0.1 | 0.2 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
0.0 | 0.3 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.0 | 2.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.4 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
0.0 | 1.0 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.0 | 0.5 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.0 | 6.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.4 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.0 | 0.1 | GO:0044388 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) small protein activating enzyme binding(GO:0044388) cupric ion binding(GO:1903135) cuprous ion binding(GO:1903136) glyoxalase (glycolic acid-forming) activity(GO:1990422) |
0.0 | 1.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 1.9 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.3 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.7 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.6 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.5 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.1 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.7 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.0 | 0.4 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 0.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |