Motif ID: Nr4a3

Z-value: 0.537


Transcription factors associated with Nr4a3:

Gene SymbolEntrez IDGene Name
Nr4a3 ENSMUSG00000028341.3 Nr4a3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a3mm10_v2_chr4_+_48049080_48049114-0.056.7e-01Click!


Activity profile for motif Nr4a3.

activity profile for motif Nr4a3


Sorted Z-values histogram for motif Nr4a3

Sorted Z-values for motif Nr4a3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr4a3

PNG image of the network

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Top targets:


Showing 1 to 20 of 91 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_154960915 6.093 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chrY_-_1245685 2.785 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
 Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr9_-_54661666 2.237 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr15_+_25773985 1.877 ENSMUST00000125667.1
 Myo10
myosin X
chr7_-_109616548 1.842 ENSMUST00000077909.1
ENSMUST00000084738.3
 St5

suppression of tumorigenicity 5

chr4_+_99955715 1.803 ENSMUST00000102783.4
 Pgm2
phosphoglucomutase 2
chr5_+_111581422 1.771 ENSMUST00000064930.3
 C130026L21Rik
RIKEN cDNA C130026L21 gene
chrY_-_1245753 1.654 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr11_-_55033398 1.428 ENSMUST00000108883.3
ENSMUST00000102727.2
 Anxa6

annexin A6

chr6_-_76497631 1.258 ENSMUST00000097218.5
 Gm9008
predicted pseudogene 9008
chr3_-_104818539 1.184 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
 Mov10



Moloney leukemia virus 10



chr11_-_100822525 1.151 ENSMUST00000107358.2
 Stat5b
signal transducer and activator of transcription 5B
chr2_+_59160838 1.107 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
 Pkp4


plakophilin 4


chr5_+_66968559 1.094 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr12_-_110978981 1.088 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
 Ankrd9


ankyrin repeat domain 9


chr1_-_152386675 1.060 ENSMUST00000015124.8
 Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr5_+_16553488 1.010 ENSMUST00000030683.3
 Hgf
hepatocyte growth factor
chr6_+_113531675 1.007 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr19_-_4334001 0.902 ENSMUST00000176653.1
 Kdm2a
lysine (K)-specific demethylase 2A
chr1_-_152386589 0.890 ENSMUST00000162371.1
 Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 6.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.5 3.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 2.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 2.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 1.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.4 1.2 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.1 1.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.9 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 0.8 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.8 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.7 GO:0014003 oligodendrocyte development(GO:0014003)
0.2 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 3.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 2.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 2.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.4 1.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.5 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)