Motif ID: Nr5a2

Z-value: 0.649


Transcription factors associated with Nr5a2:

Gene SymbolEntrez IDGene Name
Nr5a2 ENSMUSG00000026398.8 Nr5a2



Activity profile for motif Nr5a2.

activity profile for motif Nr5a2


Sorted Z-values histogram for motif Nr5a2

Sorted Z-values for motif Nr5a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr5a2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_124793013 7.186 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr8_+_124793061 6.887 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr13_-_21787218 6.570 ENSMUST00000091751.2
 Hist1h2an
histone cluster 1, H2an
chr7_-_46179929 6.465 ENSMUST00000033123.6
 Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr11_+_98741805 5.187 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr19_-_46327121 4.973 ENSMUST00000041391.4
ENSMUST00000096029.5
 Psd

pleckstrin and Sec7 domain containing

chr3_-_107517321 4.818 ENSMUST00000166892.1
 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr9_-_53975246 4.473 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chr2_+_178119166 4.438 ENSMUST00000108916.1
 Phactr3
phosphatase and actin regulator 3
chr18_+_37955544 4.438 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
 Rell2




RELT-like 2




chr11_+_58948890 4.402 ENSMUST00000078267.3
 Hist3h2ba
histone cluster 3, H2ba
chr2_+_121357714 4.402 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
 Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr13_-_21753851 4.254 ENSMUST00000074752.2
 Hist1h2ak
histone cluster 1, H2ak
chr4_+_13751297 4.227 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_54915867 4.196 ENSMUST00000070342.3
 Sertm1
serine rich and transmembrane domain containing 1
chr11_+_67586520 4.039 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr2_+_178118975 4.038 ENSMUST00000108917.1
 Phactr3
phosphatase and actin regulator 3
chr9_-_77347816 3.936 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr7_-_141429351 3.816 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
 Cend1


cell cycle exit and neuronal differentiation 1


chr15_-_79804717 3.815 ENSMUST00000023057.8
 Nptxr
neuronal pentraxin receptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 18.5 GO:0006342 chromatin silencing(GO:0006342)
0.5 14.1 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 10.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.4 9.8 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
2.1 8.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 8.4 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 8.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 7.8 GO:0051017 actin filament bundle assembly(GO:0051017)
2.4 7.1 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.2 6.0 GO:0010043 response to zinc ion(GO:0010043)
0.2 5.9 GO:1902476 chloride transmembrane transport(GO:1902476)
1.0 5.8 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
1.7 5.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.0 4.8 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.9 4.5 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 4.5 GO:0006334 nucleosome assembly(GO:0006334)
0.1 4.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 3.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 3.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 3.6 GO:0007018 microtubule-based movement(GO:0007018)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.6 GO:0000790 nuclear chromatin(GO:0000790)
0.4 8.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 7.3 GO:0005604 basement membrane(GO:0005604)
0.7 6.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 6.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 6.4 GO:0016605 PML body(GO:0016605)
0.1 5.3 GO:0000786 nucleosome(GO:0000786)
0.1 5.0 GO:0016363 nuclear matrix(GO:0016363)
0.1 4.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 4.1 GO:0005884 actin filament(GO:0005884)
0.1 3.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 3.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.7 3.3 GO:0042583 chromaffin granule(GO:0042583)
0.4 3.3 GO:0001520 outer dense fiber(GO:0001520)
0.1 3.1 GO:0005871 kinesin complex(GO:0005871)
0.1 3.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.9 2.8 GO:1990075 periciliary membrane compartment(GO:1990075)
0.2 2.8 GO:0000145 exocyst(GO:0000145)
0.6 2.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 104 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 11.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 9.1 GO:0005267 potassium channel activity(GO:0005267)
0.4 8.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 8.5 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
1.7 6.9 GO:0004111 creatine kinase activity(GO:0004111)
0.2 6.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 5.6 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.3 5.4 GO:0035613 RNA stem-loop binding(GO:0035613)
1.7 5.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.3 4.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 4.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 4.3 GO:0003777 microtubule motor activity(GO:0003777)
1.3 3.8 GO:0001847 opsonin receptor activity(GO:0001847)
0.9 3.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 3.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 3.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 2.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 2.8 GO:0000149 SNARE binding(GO:0000149)
0.0 2.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)