Motif ID: Nr6a1

Z-value: 0.486


Transcription factors associated with Nr6a1:

Gene SymbolEntrez IDGene Name
Nr6a1 ENSMUSG00000063972.7 Nr6a1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr6a1mm10_v2_chr2_-_38926217_389264540.123.3e-01Click!


Activity profile for motif Nr6a1.

activity profile for motif Nr6a1


Sorted Z-values histogram for motif Nr6a1

Sorted Z-values for motif Nr6a1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr6a1

PNG image of the network

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Top targets:


Showing 1 to 20 of 66 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_42245907 2.794 ENSMUST00000031897.5
 Gstk1
glutathione S-transferase kappa 1
chr13_-_24761440 2.750 ENSMUST00000176890.1
ENSMUST00000175689.1
 Gmnn

geminin

chr4_-_45530330 2.481 ENSMUST00000061986.5
 Shb
src homology 2 domain-containing transforming protein B
chr14_+_12189943 2.338 ENSMUST00000119888.1
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr9_-_96437434 2.251 ENSMUST00000070500.2
 BC043934
cDNA sequence BC043934
chr7_+_30314810 2.234 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
 Syne4



spectrin repeat containing, nuclear envelope family member 4



chr19_+_46707443 2.039 ENSMUST00000003655.7
 As3mt
arsenic (+3 oxidation state) methyltransferase
chr2_+_172472512 2.027 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr6_+_83349446 2.025 ENSMUST00000136501.1
 Bola3
bolA-like 3 (E. coli)
chr7_-_66427469 1.848 ENSMUST00000015278.7
 Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr17_+_72918298 1.832 ENSMUST00000024857.6
 Lbh
limb-bud and heart
chr12_+_3807017 1.660 ENSMUST00000020991.8
ENSMUST00000172509.1
 Dnmt3a

DNA methyltransferase 3A

chr5_-_137610626 1.655 ENSMUST00000142675.1
 Pcolce
procollagen C-endopeptidase enhancer protein
chr5_-_30073554 1.422 ENSMUST00000026846.6
 Tyms
thymidylate synthase
chr17_-_46645128 1.415 ENSMUST00000003642.6
 Klc4
kinesin light chain 4
chr12_+_3807076 1.407 ENSMUST00000174817.1
 Dnmt3a
DNA methyltransferase 3A
chr10_+_128083273 1.275 ENSMUST00000026459.5
 Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr18_-_77767752 1.274 ENSMUST00000048192.7
 Haus1
HAUS augmin-like complex, subunit 1
chr15_-_98165613 1.236 ENSMUST00000143400.1
 Asb8
ankyrin repeat and SOCS box-containing 8
chr5_-_5694024 1.135 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
 Steap2



six transmembrane epithelial antigen of prostate 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.4 2.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 2.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.8 2.5 GO:0009177 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0 2.3 GO:1901998 toxin transport(GO:1901998)
0.2 2.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 2.0 GO:0009404 toxin metabolic process(GO:0009404)
0.6 1.8 GO:0060166 olfactory pit development(GO:0060166)
0.6 1.8 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0 1.7 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.3 1.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 1.3 GO:0051225 spindle assembly(GO:0051225)
0.4 1.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.9 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.8 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.2 0.7 GO:0009838 abscission(GO:0009838)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.2 GO:0031012 extracellular matrix(GO:0031012)
0.1 3.1 GO:0001741 XY body(GO:0001741)
0.2 2.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.2 1.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 1.3 GO:0070652 HAUS complex(GO:0070652)
0.1 1.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.1 0.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.7 GO:0090543 Flemming body(GO:0090543)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.5 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.5 GO:0016504 peptidase activator activity(GO:0016504)
0.0 3.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 3.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 3.0 GO:0030792 methylarsonite methyltransferase activity(GO:0030792)
0.1 2.8 GO:0015035 glutathione peroxidase activity(GO:0004602) protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.6 1.8 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 1.8 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 1.4 GO:0005542 folic acid binding(GO:0005542)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 1.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905)
0.4 1.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 1.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.6 GO:0000104 succinate dehydrogenase activity(GO:0000104)