Motif ID: Pax2

Z-value: 0.865


Transcription factors associated with Pax2:

Gene SymbolEntrez IDGene Name
Pax2 ENSMUSG00000004231.9 Pax2



Activity profile for motif Pax2.

activity profile for motif Pax2


Sorted Z-values histogram for motif Pax2

Sorted Z-values for motif Pax2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_26715644 4.791 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chrX_+_166344692 3.832 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr19_-_57008187 3.480 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr10_+_111164794 3.461 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chr9_-_42124276 3.188 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr11_+_35769462 3.091 ENSMUST00000018990.7
Pank3
pantothenate kinase 3
chr18_+_34861200 2.886 ENSMUST00000165033.1
Egr1
early growth response 1
chr16_-_45158566 2.835 ENSMUST00000181177.1
Slc35a5
solute carrier family 35, member A5
chr19_-_7105729 2.778 ENSMUST00000113383.2
Flrt1
fibronectin leucine rich transmembrane protein 1
chr16_-_45158183 2.704 ENSMUST00000114600.1
Slc35a5
solute carrier family 35, member A5
chr7_+_44850393 2.660 ENSMUST00000136232.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr14_-_18239053 2.636 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr2_+_119897212 2.608 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
Mga




MAX gene associated




chr3_+_135212557 2.591 ENSMUST00000062893.7
Cenpe
centromere protein E
chr1_-_82291370 2.545 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr16_-_45158624 2.540 ENSMUST00000180636.1
Slc35a5
solute carrier family 35, member A5
chr16_-_45158650 2.467 ENSMUST00000023344.3
Slc35a5
solute carrier family 35, member A5
chr13_+_13590402 2.432 ENSMUST00000110559.1
Lyst
lysosomal trafficking regulator
chr16_+_94370786 2.425 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
Ttc3




tetratricopeptide repeat domain 3




chr5_+_15934685 2.334 ENSMUST00000078272.6
ENSMUST00000180204.1
ENSMUST00000167946.2
ENSMUST00000101581.3
ENSMUST00000039370.7
Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 100 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.2 GO:0008643 carbohydrate transport(GO:0008643)
1.8 5.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.0 4.8 GO:1900170 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
1.5 4.5 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.1 4.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.8 4.2 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.8 4.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.5 3.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 3.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.9 3.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 3.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.8 3.3 GO:0070829 heterochromatin maintenance(GO:0070829)
0.6 3.0 GO:0042117 monocyte activation(GO:0042117)
1.0 2.9 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.6 2.8 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.3 2.8 GO:0060746 parental behavior(GO:0060746)
0.0 2.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 2.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.5 2.6 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 2.6 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.1 GO:0000139 Golgi membrane(GO:0000139)
0.1 5.2 GO:0090544 BAF-type complex(GO:0090544)
1.5 4.5 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.4 4.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 4.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 3.8 GO:0031931 TORC1 complex(GO:0031931)
0.7 3.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.4 3.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 2.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) mitotic spindle midzone(GO:1990023)
0.1 2.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.8 2.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 2.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 2.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 2.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.4 1.7 GO:0031084 BLOC-2 complex(GO:0031084)
0.3 1.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 12.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 5.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 4.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.8 4.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 3.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 3.5 GO:0001786 phosphatidylserine binding(GO:0001786)
1.1 3.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.3 3.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.6 3.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 3.0 GO:0042169 SH2 domain binding(GO:0042169)
0.2 2.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.6 2.6 GO:0043515 kinetochore binding(GO:0043515)
0.4 2.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 2.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 2.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 2.2 GO:0043621 protein self-association(GO:0043621)
0.3 2.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 2.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)