Motif ID: Pax3

Z-value: 0.480


Transcription factors associated with Pax3:

Gene SymbolEntrez IDGene Name
Pax3 ENSMUSG00000004872.9 Pax3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax3mm10_v2_chr1_-_78197112_78197134-0.431.7e-04Click!


Activity profile for motif Pax3.

activity profile for motif Pax3


Sorted Z-values histogram for motif Pax3

Sorted Z-values for motif Pax3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax3

PNG image of the network

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Top targets:


Showing 1 to 20 of 35 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_136387929 4.558 ENSMUST00000035264.2
ENSMUST00000077200.3
 Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr9_-_40346290 3.667 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr14_+_51893610 3.410 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chrX_+_159840463 3.019 ENSMUST00000112451.1
ENSMUST00000112453.2
 Sh3kbp1

SH3-domain kinase binding protein 1

chr4_+_127077374 2.986 ENSMUST00000046751.6
ENSMUST00000094713.3
 Zmym6

zinc finger, MYM-type 6

chr10_+_82138253 2.451 ENSMUST00000105314.2
 AU041133
expressed sequence AU041133
chr18_+_35562158 2.285 ENSMUST00000166793.1
 Matr3
matrin 3
chr8_+_71887264 2.106 ENSMUST00000034259.7
 Zfp709
zinc finger protein 709
chrX_+_114474312 2.014 ENSMUST00000113371.1
ENSMUST00000040504.5
 Klhl4

kelch-like 4

chr2_+_168230597 2.012 ENSMUST00000099071.3
 Mocs3
molybdenum cofactor synthesis 3
chr12_+_52699297 1.967 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6
chr10_-_70592782 1.888 ENSMUST00000162251.1
 Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr1_+_176814660 1.741 ENSMUST00000056773.8
ENSMUST00000027785.8
 Sdccag8

serologically defined colon cancer antigen 8

chr7_+_120843551 1.730 ENSMUST00000106489.1
ENSMUST00000143279.1
 Eef2k

eukaryotic elongation factor-2 kinase

chr11_-_88851462 1.602 ENSMUST00000107903.1
 Akap1
A kinase (PRKA) anchor protein 1
chr17_+_21691860 1.517 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr8_-_71043040 1.375 ENSMUST00000170101.1
 Gm17576
predicted gene, 17576
chrX_-_103623648 1.325 ENSMUST00000156211.1
 Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr16_-_32877723 1.309 ENSMUST00000119810.1
 1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr11_-_58323113 1.272 ENSMUST00000108829.1
 Zfp672
zinc finger protein 672

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.1 3.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 3.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.3 GO:0003170 heart valve development(GO:0003170)
0.4 2.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 2.1 GO:0034605 cellular response to heat(GO:0034605)
0.5 2.0 GO:0018307 enzyme active site formation(GO:0018307)
0.5 2.0 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 1.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 1.7 GO:0051297 centrosome organization(GO:0051297)
0.2 1.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 1.2 GO:0071638 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.6 GO:0007413 axonal fasciculation(GO:0007413)
0.2 0.5 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular_function category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 3.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 3.0 GO:0017124 SH3 domain binding(GO:0017124)
0.4 2.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.2 2.0 GO:0043495 protein anchor(GO:0043495)
0.6 1.7 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 1.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)