Motif ID: Pax5

Z-value: 1.384


Transcription factors associated with Pax5:

Gene SymbolEntrez IDGene Name
Pax5 ENSMUSG00000014030.9 Pax5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5mm10_v2_chr4_-_44704006_447040060.171.6e-01Click!


Activity profile for motif Pax5.

activity profile for motif Pax5


Sorted Z-values histogram for motif Pax5

Sorted Z-values for motif Pax5



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_127725392 10.077 ENSMUST00000026466.3
Tac2
tachykinin 2
chr11_-_102897123 10.042 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr3_+_89520152 8.787 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_-_79386943 8.578 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr2_+_91945703 7.934 ENSMUST00000178895.1
Gm9821
predicted gene 9821
chr11_-_102897146 7.357 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr3_-_152982240 6.730 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr16_-_36784784 6.599 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr16_+_45094036 6.590 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr9_+_37367354 6.538 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr6_-_18514802 6.531 ENSMUST00000090601.5
Cttnbp2
cortactin binding protein 2
chr4_-_64046925 6.502 ENSMUST00000107377.3
Tnc
tenascin C
chr19_-_57008187 6.331 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr1_-_172297989 6.252 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr16_+_45093611 6.109 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr3_+_90537306 5.973 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr3_+_90537242 5.785 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr14_+_54936456 5.554 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr5_+_89027959 5.542 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr12_+_16653470 5.456 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 344 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 17.7 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.8 15.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 13.4 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
1.7 10.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
3.1 9.2 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.7 8.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.6 8.3 GO:0070842 aggresome assembly(GO:0070842)
0.3 8.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 7.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 7.6 GO:0008360 regulation of cell shape(GO:0008360)
0.5 6.8 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 6.8 GO:0019228 neuronal action potential(GO:0019228)
1.6 6.6 GO:0042938 dipeptide transport(GO:0042938)
2.2 6.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
2.1 6.3 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 6.1 GO:0030033 microvillus assembly(GO:0030033)
0.1 6.0 GO:0007601 visual perception(GO:0007601)
0.4 5.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 5.1 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
1.2 5.0 GO:0035617 stress granule disassembly(GO:0035617)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 151 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 25.1 GO:0045211 postsynaptic membrane(GO:0045211)
1.2 19.2 GO:0005614 interstitial matrix(GO:0005614)
4.3 17.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 15.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 15.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 12.6 GO:0031594 neuromuscular junction(GO:0031594)
0.2 10.8 GO:0031201 SNARE complex(GO:0031201)
0.1 10.8 GO:0043197 dendritic spine(GO:0043197)
0.2 9.4 GO:0005871 kinesin complex(GO:0005871)
0.1 7.3 GO:0043198 dendritic shaft(GO:0043198)
0.1 6.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 6.6 GO:0005581 collagen trimer(GO:0005581)
0.9 6.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
2.1 6.2 GO:0071953 elastic fiber(GO:0071953)
1.5 6.0 GO:0097441 basilar dendrite(GO:0097441)
0.2 5.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 5.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 4.7 GO:0035253 ciliary rootlet(GO:0035253)
0.2 4.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 4.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 219 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 26.1 GO:0005178 integrin binding(GO:0005178)
0.5 12.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 10.9 GO:0003714 transcription corepressor activity(GO:0003714)
3.3 9.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
2.3 9.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.1 9.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 9.0 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.2 8.9 GO:0003777 microtubule motor activity(GO:0003777)
1.4 8.6 GO:0019841 retinol binding(GO:0019841)
1.5 7.7 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 7.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3 7.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.9 7.0 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.8 6.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.1 6.5 GO:0045545 syndecan binding(GO:0045545)
0.8 6.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 6.5 GO:0019905 syntaxin binding(GO:0019905)
0.4 6.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 6.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 6.0 GO:0008188 neuropeptide receptor activity(GO:0008188)