Motif ID: Pax7

Z-value: 0.479


Transcription factors associated with Pax7:

Gene SymbolEntrez IDGene Name
Pax7 ENSMUSG00000028736.7 Pax7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax7mm10_v2_chr4_-_139833524_139833535-0.254.0e-02Click!


Activity profile for motif Pax7.

activity profile for motif Pax7


Sorted Z-values histogram for motif Pax7

Sorted Z-values for motif Pax7



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_67113909 6.002 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr4_-_14621805 4.445 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr4_+_102589687 2.773 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr10_+_85386813 2.614 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr3_+_55461758 2.547 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr15_-_37459327 2.459 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chr4_-_14621494 2.191 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr15_-_64922290 1.957 ENSMUST00000023007.5
 Adcy8
adenylate cyclase 8
chr4_-_14621669 1.954 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr10_-_62379852 1.860 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
 Hk1



hexokinase 1



chr5_+_26817357 1.799 ENSMUST00000071500.6
 Dpp6
dipeptidylpeptidase 6
chr2_+_65620829 1.722 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr11_-_115276973 1.636 ENSMUST00000021078.2
 Fdxr
ferredoxin reductase
chr4_+_136286061 1.446 ENSMUST00000069195.4
ENSMUST00000130658.1
 Zfp46

zinc finger protein 46

chr6_+_145934113 1.363 ENSMUST00000032383.7
 Sspn
sarcospan
chr4_+_108719649 1.157 ENSMUST00000178992.1
 3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr1_+_72284367 1.140 ENSMUST00000027380.5
ENSMUST00000141783.1
 Tmem169

transmembrane protein 169

chr5_-_92348871 1.138 ENSMUST00000038816.6
ENSMUST00000118006.1
 Cxcl10

chemokine (C-X-C motif) ligand 10

chr8_-_34965631 1.046 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr15_+_9436028 1.001 ENSMUST00000042360.3
 Capsl
calcyphosine-like
chr2_+_125136692 0.963 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr13_-_23934156 0.848 ENSMUST00000052776.2
 Hist1h2ba
histone cluster 1, H2ba
chr9_-_96719404 0.829 ENSMUST00000140121.1
 Zbtb38
zinc finger and BTB domain containing 38
chr11_-_87359011 0.753 ENSMUST00000055438.4
 Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr13_-_22042949 0.752 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr13_+_67833235 0.742 ENSMUST00000060609.7
 Gm10037
predicted gene 10037
chr19_+_8802486 0.718 ENSMUST00000172175.1
 Zbtb3
zinc finger and BTB domain containing 3
chr13_+_76579670 0.711 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr18_+_38993126 0.702 ENSMUST00000097593.2
 Arhgap26
Rho GTPase activating protein 26
chr3_+_96268654 0.697 ENSMUST00000098843.2
 Hist2h3b
histone cluster 2, H3b
chr9_-_71163224 0.642 ENSMUST00000074465.2
 Aqp9
aquaporin 9
chr8_+_107031218 0.629 ENSMUST00000034388.9
 Vps4a
vacuolar protein sorting 4a (yeast)
chr19_+_41933464 0.580 ENSMUST00000026154.7
 Zdhhc16
zinc finger, DHHC domain containing 16
chr19_-_41933276 0.464 ENSMUST00000075280.4
ENSMUST00000112123.2
 Exosc1

exosome component 1

chr14_-_76110760 0.451 ENSMUST00000022585.3
 Gpalpp1
GPALPP motifs containing 1
chr11_-_29247208 0.415 ENSMUST00000020754.3
 Ccdc104
coiled-coil domain containing 104
chr7_-_137410717 0.398 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
 9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr7_-_45510400 0.393 ENSMUST00000033096.7
 Nucb1
nucleobindin 1
chr2_+_32727682 0.363 ENSMUST00000113242.2
 Sh2d3c
SH2 domain containing 3C
chr17_+_35517100 0.353 ENSMUST00000164242.2
ENSMUST00000045956.7
 Cchcr1

coiled-coil alpha-helical rod protein 1

chr2_-_33718789 0.257 ENSMUST00000130532.1
 9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr13_+_23533869 0.250 ENSMUST00000073261.2
 Hist1h2af
histone cluster 1, H2af
chr2_-_150255591 0.216 ENSMUST00000063463.5
 Gm21994
predicted gene 21994
chr13_+_75707484 0.214 ENSMUST00000001583.6
 Ell2
elongation factor RNA polymerase II 2
chr2_-_37359274 0.206 ENSMUST00000009174.8
 Pdcl
phosducin-like
chr9_-_96719549 0.180 ENSMUST00000128269.1
 Zbtb38
zinc finger and BTB domain containing 38
chr7_+_19228334 0.178 ENSMUST00000063976.8
 Opa3
optic atrophy 3
chr14_+_76110885 0.144 ENSMUST00000022586.1
 Nufip1
nuclear fragile X mental retardation protein interacting protein 1
chr7_-_98656530 0.144 ENSMUST00000038359.4
 2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr11_+_116843278 0.108 ENSMUST00000106370.3
 Mettl23
methyltransferase like 23
chr3_-_129755305 0.103 ENSMUST00000029653.2
 Egf
epidermal growth factor
chr7_-_19715395 0.089 ENSMUST00000032555.9
ENSMUST00000093552.5
 Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr12_+_72441852 0.050 ENSMUST00000162159.1
 Lrrc9
leucine rich repeat containing 9
chr13_-_102906046 0.047 ENSMUST00000171791.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr13_+_22043189 0.007 ENSMUST00000110452.1
 Hist1h2bj
histone cluster 1, H2bj

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.6 GO:0019532 oxalate transport(GO:0019532)
0.4 1.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.4 1.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.3 1.0 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.3 1.6 GO:0010359 regulation of anion channel activity(GO:0010359)
0.3 6.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.6 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0015791 polyol transport(GO:0015791) urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.1 0.2 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 2.0 GO:0007616 long-term memory(GO:0007616)
0.0 1.8 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 2.6 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.1 GO:0007262 STAT protein import into nucleus(GO:0007262) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 6.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.9 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.6 GO:0090543 Flemming body(GO:0090543)
0.1 1.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 1.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 9.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.8 6.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 1.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 1.9 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 2.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.6 GO:0015265 urea channel activity(GO:0015265)
0.1 1.6 GO:0070402 NADPH binding(GO:0070402)
0.1 2.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 2.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)