Motif ID: Pax8

Z-value: 0.442


Transcription factors associated with Pax8:

Gene SymbolEntrez IDGene Name
Pax8 ENSMUSG00000026976.9 Pax8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax8mm10_v2_chr2_-_24475564_24475580-0.291.4e-02Click!


Activity profile for motif Pax8.

activity profile for motif Pax8


Sorted Z-values histogram for motif Pax8

Sorted Z-values for motif Pax8



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_6961160 2.924 ENSMUST00000054055.6
 Usp29
ubiquitin specific peptidase 29
chr7_-_42578588 2.503 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr11_-_69801716 1.767 ENSMUST00000011285.4
ENSMUST00000102585.1
 Fgf11

fibroblast growth factor 11

chr18_-_66860458 1.752 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr18_-_12121460 1.677 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
 Tmem241


transmembrane protein 241


chr17_+_45555693 1.500 ENSMUST00000024742.7
 Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr11_+_24080664 1.341 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr7_+_114768736 1.263 ENSMUST00000117543.1
 Insc
inscuteable homolog (Drosophila)
chr12_+_71048338 1.055 ENSMUST00000135709.1
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr17_+_21691860 0.931 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr2_+_128967383 0.883 ENSMUST00000110320.2
ENSMUST00000110319.2
 Zc3h6

zinc finger CCCH type containing 6

chr1_+_65186727 0.872 ENSMUST00000097707.4
ENSMUST00000081154.7
 Pikfyve

phosphoinositide kinase, FYVE finger containing

chr1_+_6487231 0.815 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr7_-_42706369 0.806 ENSMUST00000180131.1
 Gm17067
predicted gene 17067
chr9_-_103230415 0.795 ENSMUST00000035158.9
 Trf
transferrin
chrX_-_105391770 0.763 ENSMUST00000136406.1
ENSMUST00000150604.1
 5330434G04Rik

RIKEN cDNA 5330434G04 gene

chr13_-_66852017 0.725 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr9_+_32116040 0.703 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr13_-_25270076 0.691 ENSMUST00000057866.6
 Nrsn1
neurensin 1
chr7_-_29906087 0.679 ENSMUST00000053521.8
 Zfp27
zinc finger protein 27
chr4_+_6191093 0.549 ENSMUST00000029907.5
 Ubxn2b
UBX domain protein 2B
chrX_-_105391726 0.498 ENSMUST00000142109.1
 5330434G04Rik
RIKEN cDNA 5330434G04 gene
chr9_+_109052828 0.489 ENSMUST00000124432.1
 Shisa5
shisa homolog 5 (Xenopus laevis)
chr13_-_62777089 0.485 ENSMUST00000167516.2
 Gm5141
predicted gene 5141
chr4_+_103313806 0.460 ENSMUST00000035780.3
 Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr13_-_62607499 0.432 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr13_-_62520451 0.407 ENSMUST00000082203.6
ENSMUST00000101547.4
 Zfp934

zinc finger protein 934

chrX_-_7572843 0.398 ENSMUST00000132788.1
 Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr10_+_18845071 0.389 ENSMUST00000019998.7
 Perp
PERP, TP53 apoptosis effector
chr19_+_46075842 0.349 ENSMUST00000165017.1
 Nolc1
nucleolar and coiled-body phosphoprotein 1
chr2_+_143915273 0.322 ENSMUST00000103172.3
 Dstn
destrin
chr5_+_100196611 0.309 ENSMUST00000066813.1
 Gm9932
predicted gene 9932
chr8_-_64849818 0.299 ENSMUST00000034017.7
 Klhl2
kelch-like 2, Mayven
chr12_-_20900867 0.286 ENSMUST00000079237.5
 Zfp125
zinc finger protein 125
chr4_+_156215920 0.261 ENSMUST00000105572.1
 2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr4_+_59805829 0.259 ENSMUST00000030080.6
 Snx30
sorting nexin family member 30
chr16_-_30587537 0.217 ENSMUST00000117363.2
 Lsg1
large subunit GTPase 1 homolog (S. cerevisiae)
chr10_+_82378593 0.096 ENSMUST00000165906.1
 Gm4924
predicted gene 4924
chr9_-_103230262 0.087 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
 Trf

Gm20425
transferrin

predicted gene 20425

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.2 1.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 1.5 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.9 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.1 1.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:0002934 desmosome organization(GO:0002934)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.9 GO:0032288 myelin assembly(GO:0032288)
0.0 0.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 1.3 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 2.9 GO:0016579 protein deubiquitination(GO:0016579)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0097433 dense body(GO:0097433)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.9 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.4 GO:2001069 glycogen binding(GO:2001069)
0.0 2.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.8 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0008758 thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)