Motif ID: Pgr_Nr3c1

Z-value: 0.466

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39487096_394872450.056.5e-01Click!


Activity profile for motif Pgr_Nr3c1.

activity profile for motif Pgr_Nr3c1


Sorted Z-values histogram for motif Pgr_Nr3c1

Sorted Z-values for motif Pgr_Nr3c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 131 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 7.650 ENSMUST00000075312.3
 Ttr
transthyretin
chr10_+_97565436 5.624 ENSMUST00000038160.4
 Lum
lumican
chr5_+_24364804 1.439 ENSMUST00000030834.4
ENSMUST00000115090.1
 Nos3

nitric oxide synthase 3, endothelial cell

chr14_-_16575456 1.356 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr9_-_79718631 1.238 ENSMUST00000180083.1
 Col12a1
collagen, type XII, alpha 1
chr7_-_142576492 1.234 ENSMUST00000140716.1
 H19
H19 fetal liver mRNA
chr2_-_122611238 1.200 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr4_-_136898803 1.199 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr9_-_79718518 1.108 ENSMUST00000071750.6
 Col12a1
collagen, type XII, alpha 1
chr9_-_79718720 1.009 ENSMUST00000121227.1
 Col12a1
collagen, type XII, alpha 1
chr13_-_84064772 0.899 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr7_+_144838590 0.880 ENSMUST00000105898.1
 Fgf3
fibroblast growth factor 3
chr14_+_99298652 0.869 ENSMUST00000005279.6
 Klf5
Kruppel-like factor 5
chr13_+_91461050 0.853 ENSMUST00000004094.8
ENSMUST00000042122.8
 Ssbp2

single-stranded DNA binding protein 2

chr11_-_110168073 0.851 ENSMUST00000044850.3
 Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr7_-_109616548 0.824 ENSMUST00000077909.1
ENSMUST00000084738.3
 St5

suppression of tumorigenicity 5

chr9_+_91368970 0.717 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr9_+_91368811 0.716 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr17_-_68004075 0.690 ENSMUST00000024840.5
 Arhgap28
Rho GTPase activating protein 28
chr12_-_73047179 0.674 ENSMUST00000050029.7
 Six1
sine oculis-related homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 7.6 GO:0070327 thyroid hormone transport(GO:0070327)
1.4 5.6 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.5 1.4 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.2 1.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.4 1.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 1.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 1.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.1 GO:0030916 otic vesicle formation(GO:0030916)
0.2 0.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.9 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.3 0.8 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 0.7 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.2 0.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.6 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.6 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.5 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.1 3.4 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 7.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 5.6 GO:0005518 collagen binding(GO:0005518)
0.5 1.4 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.1 1.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.2 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.9 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.6 GO:0045340 mercury ion binding(GO:0045340)
0.1 0.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.5 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.5 GO:0048038 quinone binding(GO:0048038)
0.1 0.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)