Motif ID: Pitx1

Z-value: 0.641


Transcription factors associated with Pitx1:

Gene SymbolEntrez IDGene Name
Pitx1 ENSMUSG00000021506.7 Pitx1



Activity profile for motif Pitx1.

activity profile for motif Pitx1


Sorted Z-values histogram for motif Pitx1

Sorted Z-values for motif Pitx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 182 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 6.560 ENSMUST00000107377.3
Tnc
tenascin C
chr4_-_137766474 5.577 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr6_-_93913678 5.222 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr15_-_79164477 5.101 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr2_+_14388316 5.077 ENSMUST00000114731.1
ENSMUST00000082290.7
Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr2_+_102658640 4.363 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr18_+_73863672 3.880 ENSMUST00000134847.1
Mro
maestro
chr5_+_3343893 3.733 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr17_+_75005523 3.719 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr14_-_31640878 3.705 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr5_+_3344194 3.474 ENSMUST00000042410.4
Cdk6
cyclin-dependent kinase 6
chr1_-_155232710 3.452 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr7_-_4752972 3.348 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr14_+_27039001 3.327 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr13_-_97747373 3.163 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_+_74542881 2.917 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
Plcd4




phospholipase C, delta 4




chr7_+_30553263 2.911 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr16_-_10313940 2.782 ENSMUST00000078357.4
Emp2
epithelial membrane protein 2
chr2_+_119325784 2.769 ENSMUST00000102517.3
Dll4
delta-like 4 (Drosophila)
chr14_-_118052235 2.759 ENSMUST00000022725.2
Dct
dopachrome tautomerase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 7.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.6 7.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.6 6.7 GO:0042572 retinol metabolic process(GO:0042572)
1.3 6.6 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 5.6 GO:0046677 response to antibiotic(GO:0046677)
0.4 5.1 GO:0048484 enteric nervous system development(GO:0048484)
0.7 4.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.6 3.8 GO:0003383 apical constriction(GO:0003383)
0.7 3.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 3.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 3.7 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 2.9 GO:0007340 acrosome reaction(GO:0007340)
0.9 2.8 GO:0072554 blood vessel lumenization(GO:0072554)
0.5 2.8 GO:0006570 tyrosine metabolic process(GO:0006570)
0.3 2.8 GO:0003093 regulation of glomerular filtration(GO:0003093)
0.7 2.6 GO:0003360 brainstem development(GO:0003360)
0.1 2.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.4 2.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 2.4 GO:0097154 GABAergic neuron differentiation(GO:0097154)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 6.6 GO:0005614 interstitial matrix(GO:0005614)
0.3 5.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.6 5.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 4.9 GO:0016324 apical plasma membrane(GO:0016324)
0.1 4.4 GO:0030673 axolemma(GO:0030673)
0.5 3.8 GO:0033269 internode region of axon(GO:0033269)
1.2 3.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 3.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 2.9 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 2.7 GO:0005652 nuclear lamina(GO:0005652)
0.9 2.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 2.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 1.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.6 GO:0010369 chromocenter(GO:0010369)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.2 GO:0030332 cyclin binding(GO:0030332)
0.3 7.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.0 6.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.1 6.6 GO:0045545 syndecan binding(GO:0045545)
1.4 5.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 5.2 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 4.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
1.1 4.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 4.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.9 3.7 GO:0050436 microfibril binding(GO:0050436)
0.4 3.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.4 3.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.1 3.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 3.2 GO:0005112 Notch binding(GO:0005112)
0.0 3.0 GO:0017124 SH3 domain binding(GO:0017124)
0.2 2.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 2.8 GO:0005178 integrin binding(GO:0005178)
0.1 2.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 2.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 2.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)