Motif ID: Pitx2_Otx2

Z-value: 1.614

Transcription factors associated with Pitx2_Otx2:

Gene SymbolEntrez IDGene Name
Otx2 ENSMUSG00000021848.9 Otx2
Pitx2 ENSMUSG00000028023.10 Pitx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Otx2mm10_v2_chr14_-_48662740_486628720.709.9e-12Click!
Pitx2mm10_v2_chr3_+_129199878_1291999130.667.3e-10Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx2_Otx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_75782080 27.025 ENSMUST00000181224.1
AU020206
expressed sequence AU020206
chr6_-_88898664 22.021 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr2_+_164562579 19.750 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr11_-_106998483 18.911 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr9_-_70421533 15.184 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr6_+_34354119 14.895 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr9_+_119357381 14.734 ENSMUST00000039610.8
Xylb
xylulokinase homolog (H. influenzae)
chr4_-_117182623 14.328 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr17_+_35861318 13.649 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr17_+_87635974 12.736 ENSMUST00000053577.8
Epcam
epithelial cell adhesion molecule
chr11_-_60811228 12.016 ENSMUST00000018744.8
Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr14_-_20181773 11.961 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr14_-_47411666 11.342 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr10_-_77089428 11.221 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr18_+_34751803 11.203 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr11_+_97029925 10.918 ENSMUST00000021249.4
Scrn2
secernin 2
chr16_+_30065333 10.834 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr10_-_128180265 10.722 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr17_+_35861343 10.345 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr1_+_135232045 10.241 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr17_+_80127447 10.011 ENSMUST00000039205.4
Galm
galactose mutarotase
chr7_+_16781341 9.840 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr14_-_47418407 9.715 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr18_-_74207771 9.528 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr7_-_99353104 9.430 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr18_-_60501983 9.256 ENSMUST00000042710.6
Smim3
small integral membrane protein 3
chr10_+_128238034 9.246 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr19_-_41896132 9.107 ENSMUST00000038677.3
Rrp12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr8_+_114133557 8.887 ENSMUST00000073521.5
ENSMUST00000066514.6
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr3_+_116878227 8.852 ENSMUST00000040260.6
Frrs1
ferric-chelate reductase 1
chr6_-_23248264 8.605 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr3_-_36571952 8.550 ENSMUST00000029270.3
Ccna2
cyclin A2
chr7_+_16992708 8.300 ENSMUST00000094805.4
Ccdc8
coiled-coil domain containing 8
chr8_+_114133635 8.204 ENSMUST00000147605.1
ENSMUST00000134593.1
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr14_+_27039001 8.183 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr16_+_59471775 8.035 ENSMUST00000023407.5
ENSMUST00000120667.1
ENSMUST00000120674.1
Mina


myc induced nuclear antigen


chr4_-_149137536 7.803 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
Apitd1



apoptosis-inducing, TAF9-like domain 1



chr3_-_153912966 7.783 ENSMUST00000089950.4
Rabggtb
RAB geranylgeranyl transferase, b subunit
chr6_-_124814288 7.718 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chr3_+_85915722 7.660 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr7_-_144738520 7.544 ENSMUST00000118556.2
ENSMUST00000033393.8
Ano1

anoctamin 1, calcium activated chloride channel

chr1_-_175979114 7.514 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr15_+_80948484 7.501 ENSMUST00000023043.2
ENSMUST00000168756.1
ENSMUST00000164806.1
Adsl


adenylosuccinate lyase


chr10_+_62947011 7.332 ENSMUST00000131422.1
Dna2
DNA replication helicase 2 homolog (yeast)
chr14_+_55824795 7.265 ENSMUST00000024179.5
ENSMUST00000172271.1
Nfatc4

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

chr6_+_56017489 7.121 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr8_+_33653238 7.101 ENSMUST00000033992.8
Gsr
glutathione reductase
chr3_+_55112080 7.088 ENSMUST00000044116.7
ENSMUST00000107971.2
ENSMUST00000118118.1
Spg20


spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)


chr2_+_26586607 7.010 ENSMUST00000174211.1
ENSMUST00000145575.2
ENSMUST00000173920.1
Egfl7


EGF-like domain 7


chr8_+_127447669 6.941 ENSMUST00000159511.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr5_+_110330697 6.675 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr3_-_97610156 6.622 ENSMUST00000029730.4
Chd1l
chromodomain helicase DNA binding protein 1-like
chr11_-_106999482 6.591 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr14_+_7817957 6.536 ENSMUST00000052678.8
Flnb
filamin, beta
chr10_-_92722356 6.528 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr11_+_117199641 6.452 ENSMUST00000093907.4
Sept9
septin 9
chr8_-_116993459 6.378 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr15_+_25752860 6.363 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chr9_-_100486788 6.343 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr7_+_46841475 6.322 ENSMUST00000147535.1
Ldha
lactate dehydrogenase A
chr11_-_106999369 6.288 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr7_-_144738478 6.277 ENSMUST00000121758.1
Ano1
anoctamin 1, calcium activated chloride channel
chr8_-_71511762 6.262 ENSMUST00000048452.4
Plvap
plasmalemma vesicle associated protein
chr10_+_20347788 6.213 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr15_-_82244716 6.210 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr3_+_131112785 6.123 ENSMUST00000098611.3
Lef1
lymphoid enhancer binding factor 1
chr1_-_119648903 6.082 ENSMUST00000163147.1
ENSMUST00000052404.6
ENSMUST00000027632.7
Epb4.1l5


erythrocyte protein band 4.1-like 5


chr18_+_34736359 6.036 ENSMUST00000105038.2
Gm3550
predicted gene 3550
chr17_+_50698525 6.018 ENSMUST00000061681.7
Gm7334
predicted gene 7334
chr7_-_38107490 5.994 ENSMUST00000108023.3
Ccne1
cyclin E1
chr10_+_80292453 5.986 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15

ribosomal protein S15

chr11_+_101442298 5.960 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr1_-_153549697 5.950 ENSMUST00000041874.7
Npl
N-acetylneuraminate pyruvate lyase
chr17_-_25727364 5.906 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr4_+_136143497 5.878 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr4_+_89137122 5.758 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr7_-_118116128 5.719 ENSMUST00000128482.1
ENSMUST00000131840.1
Rps15a

ribosomal protein S15A

chr5_+_134582690 5.666 ENSMUST00000023867.6
Rfc2
replication factor C (activator 1) 2
chr15_-_36308956 5.649 ENSMUST00000090170.4
Rpl7a-ps3
ribosomal protein L7A, pseudogene 3
chr7_-_143460989 5.626 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr12_+_118846329 5.600 ENSMUST00000063918.2
Sp8
trans-acting transcription factor 8
chr2_+_157737401 5.594 ENSMUST00000029178.6
Ctnnbl1
catenin, beta like 1
chr15_-_102667749 5.570 ENSMUST00000075630.3
Atp5g2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr2_+_174415804 5.555 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr19_-_47919269 5.543 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr17_-_35673738 5.542 ENSMUST00000001565.8
Gtf2h4
general transcription factor II H, polypeptide 4
chr16_+_38562806 5.488 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr11_-_73138245 5.434 ENSMUST00000052140.2
Gsg2
germ cell-specific gene 2
chr16_-_4719078 5.419 ENSMUST00000120056.1
ENSMUST00000074970.7
Nmral1

NmrA-like family domain containing 1

chr4_-_15945359 5.415 ENSMUST00000029877.8
Decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr11_-_102925086 5.387 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr5_-_134456702 5.376 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr6_-_124779686 5.279 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr17_-_70924958 5.268 ENSMUST00000180468.1
Gm26510
predicted gene, 26510
chr10_+_82954344 5.239 ENSMUST00000095396.3
Gm4799
predicted gene 4799
chr7_+_102225812 5.229 ENSMUST00000142873.1
Pgap2
post-GPI attachment to proteins 2
chr8_+_122376676 5.216 ENSMUST00000176629.1
Zc3h18
zinc finger CCCH-type containing 18
chr16_+_38562821 5.174 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr7_-_19770509 5.163 ENSMUST00000003061.7
Bcam
basal cell adhesion molecule
chr6_+_149582012 5.123 ENSMUST00000144085.2
Gm21814
predicted gene, 21814
chr11_+_115403734 5.121 ENSMUST00000153983.1
ENSMUST00000106539.3
ENSMUST00000103036.4
Ict1


immature colon carcinoma transcript 1


chr14_+_74735641 5.103 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr5_-_137611372 5.075 ENSMUST00000054564.6
Pcolce
procollagen C-endopeptidase enhancer protein
chr11_-_120796369 5.074 ENSMUST00000143139.1
ENSMUST00000129955.1
ENSMUST00000026151.4
ENSMUST00000167023.1
ENSMUST00000106133.1
ENSMUST00000106135.1
Dus1l





dihydrouridine synthase 1-like (S. cerevisiae)





chr7_-_127122226 5.025 ENSMUST00000032912.5
Qprt
quinolinate phosphoribosyltransferase
chr6_-_72235559 5.018 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr5_+_107900502 4.972 ENSMUST00000082223.6
Rpl5
ribosomal protein L5
chr15_-_76639840 4.966 ENSMUST00000166974.1
ENSMUST00000168185.1
Tonsl

tonsoku-like, DNA repair protein

chr12_+_109734969 4.966 ENSMUST00000182268.1
ENSMUST00000181543.2
ENSMUST00000183116.1
Mirg


miRNA containing gene


chr8_-_105707933 4.954 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr16_-_4719148 4.952 ENSMUST00000115851.3
Nmral1
NmrA-like family domain containing 1
chr6_+_83349446 4.936 ENSMUST00000136501.1
Bola3
bolA-like 3 (E. coli)
chr7_+_16891755 4.921 ENSMUST00000078182.4
Gng8
guanine nucleotide binding protein (G protein), gamma 8
chr11_-_40695203 4.917 ENSMUST00000101347.3
Mat2b
methionine adenosyltransferase II, beta
chr14_+_47472547 4.911 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr9_-_114982739 4.903 ENSMUST00000053150.5
Gm9846
predicted gene 9846
chr2_-_34913976 4.876 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr6_+_42350000 4.830 ENSMUST00000164375.1
Zyx
zyxin
chr8_+_71406003 4.815 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr5_-_137611429 4.742 ENSMUST00000031731.7
Pcolce
procollagen C-endopeptidase enhancer protein
chr2_+_158610731 4.708 ENSMUST00000045738.4
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr8_+_84901928 4.666 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr3_-_115715031 4.666 ENSMUST00000055676.2
S1pr1
sphingosine-1-phosphate receptor 1
chr4_+_108579445 4.657 ENSMUST00000102744.3
Orc1
origin recognition complex, subunit 1
chr17_+_80224441 4.608 ENSMUST00000069486.6
Gemin6
gem (nuclear organelle) associated protein 6
chr7_-_126792469 4.574 ENSMUST00000032936.6
Ppp4c
protein phosphatase 4, catalytic subunit
chrX_-_7967817 4.559 ENSMUST00000033502.7
Gata1
GATA binding protein 1
chr14_+_65806066 4.555 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr6_+_42349826 4.554 ENSMUST00000070635.6
Zyx
zyxin
chr5_-_125294107 4.512 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr11_-_5152218 4.443 ENSMUST00000163299.1
ENSMUST00000062821.6
Emid1

EMI domain containing 1

chr15_+_76879232 4.403 ENSMUST00000023179.5
Zfp7
zinc finger protein 7
chr10_-_80320506 4.364 ENSMUST00000020341.8
2310011J03Rik
RIKEN cDNA 2310011J03 gene
chr1_-_128102412 4.348 ENSMUST00000112538.1
ENSMUST00000086614.5
Zranb3

zinc finger, RAN-binding domain containing 3

chr12_-_69159109 4.328 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr1_-_93342734 4.318 ENSMUST00000027493.3
Pask
PAS domain containing serine/threonine kinase
chr17_-_25880236 4.296 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr7_+_66060338 4.251 ENSMUST00000153609.1
Snrpa1
small nuclear ribonucleoprotein polypeptide A'
chr9_-_96478660 4.208 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chrM_+_8600 4.168 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr17_+_24426676 4.116 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr9_-_78489141 4.111 ENSMUST00000154207.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr4_-_116994374 4.081 ENSMUST00000030446.8
Urod
uroporphyrinogen decarboxylase
chr17_+_34263209 4.078 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr9_-_20898592 4.073 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr9_+_54950782 4.071 ENSMUST00000034848.7
Psma4
proteasome (prosome, macropain) subunit, alpha type 4
chr11_-_93965957 4.066 ENSMUST00000021220.3
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr4_+_156109971 4.043 ENSMUST00000072554.6
ENSMUST00000169550.1
ENSMUST00000105576.1
9430015G10Rik


RIKEN cDNA 9430015G10 gene


chr5_-_44099220 4.019 ENSMUST00000165909.1
Prom1
prominin 1
chr9_-_96478596 4.018 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr14_-_25927672 4.012 ENSMUST00000185006.1
Tmem254a
transmembrane protein 254a
chr9_-_44344159 3.983 ENSMUST00000077353.7
Hmbs
hydroxymethylbilane synthase
chr5_-_139460501 3.966 ENSMUST00000066052.7
3110082I17Rik
RIKEN cDNA 3110082I17 gene
chr7_+_27486910 3.950 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr6_+_134929118 3.943 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr7_-_99238564 3.926 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr18_-_20682963 3.907 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr7_-_34230281 3.901 ENSMUST00000038027.4
Gpi1
glucose phosphate isomerase 1
chr11_+_69995874 3.882 ENSMUST00000101526.2
Phf23
PHD finger protein 23
chr9_-_27155418 3.876 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr16_+_32419696 3.858 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1d2

Tctex1 domain containing 2

chr10_+_7667503 3.834 ENSMUST00000040135.8
Nup43
nucleoporin 43
chr11_+_69995777 3.824 ENSMUST00000018716.3
Phf23
PHD finger protein 23
chr11_+_32205411 3.799 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr10_-_40302186 3.789 ENSMUST00000099945.4
Amd1
S-adenosylmethionine decarboxylase 1
chr6_+_134929089 3.782 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr3_+_95111013 3.779 ENSMUST00000009102.8
Vps72
vacuolar protein sorting 72 (yeast)
chr1_+_17727034 3.778 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr3_-_138131356 3.767 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr9_-_107635330 3.760 ENSMUST00000055704.6
Gnai2
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr19_+_40831296 3.758 ENSMUST00000119316.1
Ccnj
cyclin J
chr8_-_70510552 3.744 ENSMUST00000125184.1
Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr6_-_134792596 3.740 ENSMUST00000100857.3
Dusp16
dual specificity phosphatase 16
chr9_+_54950808 3.734 ENSMUST00000172407.1
Psma4
proteasome (prosome, macropain) subunit, alpha type 4
chr10_-_12861735 3.732 ENSMUST00000076817.4
Utrn
utrophin
chr16_+_14906622 3.720 ENSMUST00000090277.1
Efcab1
EF hand calcium binding domain 1
chr7_-_66388286 3.703 ENSMUST00000015277.7
Lrrk1
leucine-rich repeat kinase 1
chr5_-_135251209 3.701 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr3_-_63899437 3.674 ENSMUST00000159188.1
ENSMUST00000177143.1
Plch1

phospholipase C, eta 1

chr11_-_77725281 3.666 ENSMUST00000078623.4
Cryba1
crystallin, beta A1
chr2_+_163122605 3.646 ENSMUST00000144092.1
Gm11454
predicted gene 11454
chr11_+_51619731 3.638 ENSMUST00000127405.1
Nhp2
NHP2 ribonucleoprotein
chr5_-_8422582 3.633 ENSMUST00000168500.1
ENSMUST00000002368.9
Dbf4

DBF4 homolog (S. cerevisiae)

chr3_+_93520473 3.619 ENSMUST00000029515.4
S100a11
S100 calcium binding protein A11 (calgizzarin)
chr5_-_121618865 3.605 ENSMUST00000041252.6
ENSMUST00000111776.1
Acad12

acyl-Coenzyme A dehydrogenase family, member 12

chr5_-_25705791 3.590 ENSMUST00000030773.7
Xrcc2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr11_+_96789149 3.581 ENSMUST00000093943.3
Cbx1
chromobox 1
chr4_+_80910646 3.579 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr9_-_21149894 3.565 ENSMUST00000019615.9
Cdc37
cell division cycle 37
chr5_+_135725713 3.563 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr11_-_68973840 3.559 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr14_+_63860290 3.533 ENSMUST00000022528.4
Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr5_+_140331860 3.531 ENSMUST00000071881.3
ENSMUST00000050205.5
ENSMUST00000110827.1
Nudt1


nudix (nucleoside diphosphate linked moiety X)-type motif 1


chr11_-_116274102 3.520 ENSMUST00000106425.3
Srp68
signal recognition particle 68
chr11_+_61956779 3.517 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr4_-_117156144 3.513 ENSMUST00000102696.4
Rps8
ribosomal protein S8
chr5_-_8422695 3.494 ENSMUST00000171808.1
Dbf4
DBF4 homolog (S. cerevisiae)
chr11_-_98625661 3.494 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr19_+_40831248 3.491 ENSMUST00000025983.6
ENSMUST00000120057.1
Ccnj

cyclin J

chr2_+_104069819 3.437 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
5.6 16.8 GO:0042732 D-xylose metabolic process(GO:0042732)
5.0 14.9 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
4.0 12.0 GO:0009177 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
3.6 10.8 GO:0021557 oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
3.2 12.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
2.9 8.7 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
2.9 14.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
2.8 13.8 GO:0015705 iodide transport(GO:0015705)
2.6 7.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
2.4 7.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
2.4 7.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
2.3 4.6 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
2.1 8.6 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
2.1 6.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.1 6.3 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
2.0 6.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
2.0 3.9 GO:0014016 neuroblast differentiation(GO:0014016)
1.9 1.9 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
1.8 5.4 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
1.8 5.3 GO:0006597 spermine biosynthetic process(GO:0006597)
1.7 3.5 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.7 5.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
1.7 22.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.7 5.0 GO:0046874 quinolinate metabolic process(GO:0046874)
1.7 8.3 GO:0006167 AMP biosynthetic process(GO:0006167)
1.6 4.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.6 4.8 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) glyoxal catabolic process(GO:1903190) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) positive regulation of androgen receptor activity(GO:2000825)
1.6 9.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.6 4.7 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.6 4.7 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.5 4.5 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
1.4 4.3 GO:0036292 DNA rewinding(GO:0036292)
1.4 7.2 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
1.4 11.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.4 5.8 GO:0006166 purine ribonucleoside salvage(GO:0006166)
1.4 8.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.4 7.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.3 4.0 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
1.3 6.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
1.3 6.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.3 32.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
1.3 5.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
1.3 5.1 GO:0002339 B cell selection(GO:0002339)
1.2 12.5 GO:0006012 galactose metabolic process(GO:0006012)
1.2 3.7 GO:0007525 somatic muscle development(GO:0007525)
1.2 7.4 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
1.2 3.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.2 12.0 GO:0030322 stabilization of membrane potential(GO:0030322)
1.2 3.5 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
1.2 6.9 GO:0003383 apical constriction(GO:0003383)
1.1 7.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
1.1 5.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.0 6.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.0 4.9 GO:0019236 response to pheromone(GO:0019236)
0.9 3.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.9 2.7 GO:0031627 telomeric loop formation(GO:0031627)
0.9 3.6 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.9 2.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.9 3.5 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.9 2.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.8 4.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.8 6.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.8 2.4 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.8 6.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.8 3.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.7 3.0 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.7 2.9 GO:0042462 photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.7 8.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.7 2.9 GO:0030576 Cajal body organization(GO:0030576)
0.7 2.1 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.7 7.0 GO:0018065 protein-cofactor linkage(GO:0018065)
0.7 10.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.7 2.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.7 5.5 GO:0033504 floor plate development(GO:0033504)
0.7 3.4 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.7 8.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.7 8.2 GO:0015825 L-serine transport(GO:0015825)
0.7 19.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.7 1.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.7 2.0 GO:0045472 response to ether(GO:0045472)
0.7 2.0 GO:0006407 rRNA export from nucleus(GO:0006407)
0.6 3.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.6 3.2 GO:0090666 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.6 1.9 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.6 5.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 2.5 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.6 3.1 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.6 3.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.6 1.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.6 1.8 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.6 3.5 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.6 2.3 GO:0014012 negative regulation of Schwann cell proliferation(GO:0010626) peripheral nervous system axon regeneration(GO:0014012)
0.6 5.7 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.6 2.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.6 3.9 GO:0006071 glycerol metabolic process(GO:0006071)
0.6 5.6 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.6 1.7 GO:0009071 serine family amino acid catabolic process(GO:0009071)
0.5 2.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.5 6.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.5 1.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.5 3.2 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.5 1.6 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.5 2.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.5 2.6 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.5 1.5 GO:0009644 response to high light intensity(GO:0009644)
0.5 1.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.5 1.5 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.5 1.5 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.5 7.0 GO:0046697 decidualization(GO:0046697)
0.5 3.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.5 3.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.5 4.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.5 6.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.5 8.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.5 2.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.5 1.5 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.5 4.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.5 1.9 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.5 8.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.5 1.4 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.5 5.2 GO:0070836 caveola assembly(GO:0070836)
0.5 2.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.5 2.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.5 3.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 4.5 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.4 1.3 GO:0006545 glycine biosynthetic process(GO:0006545)
0.4 2.7 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.4 1.3 GO:0000059 protein import into nucleus, docking(GO:0000059)
0.4 3.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.4 1.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.4 3.0 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.4 2.9 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.4 2.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 3.8 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.4 1.7 GO:0031424 keratinization(GO:0031424)
0.4 2.5 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.4 1.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 1.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.4 2.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.4 1.6 GO:0035356 positive regulation of sequestering of triglyceride(GO:0010890) cellular triglyceride homeostasis(GO:0035356)
0.4 9.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.4 2.0 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 0.8 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.4 2.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.4 3.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.4 3.1 GO:0070475 rRNA base methylation(GO:0070475)
0.4 5.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.4 6.5 GO:0003334 keratinocyte development(GO:0003334)
0.4 2.7 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.4 3.0 GO:0007000 nucleolus organization(GO:0007000)
0.4 5.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 2.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.4 5.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.4 1.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.4 13.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.4 4.4 GO:0031297 replication fork processing(GO:0031297)
0.4 3.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.4 1.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.4 1.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.4 2.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.4 1.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.4 3.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.4 1.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.4 1.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.4 2.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.3 1.0 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152)
0.3 2.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.3 1.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 1.4 GO:0006788 heme oxidation(GO:0006788)
0.3 0.3 GO:0006702 androgen biosynthetic process(GO:0006702)
0.3 1.7 GO:0008343 adult feeding behavior(GO:0008343)
0.3 2.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.3 3.0 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.3 1.0 GO:0051155 positive regulation of myotube differentiation(GO:0010831) positive regulation of striated muscle cell differentiation(GO:0051155)
0.3 1.0 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.3 3.9 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.3 2.3 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.3 7.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.3 1.3 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.3 3.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3 3.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 1.2 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.3 3.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 4.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 5.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 0.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.3 3.7 GO:0036035 osteoclast development(GO:0036035)
0.3 3.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 1.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.3 5.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.3 1.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.3 7.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.3 3.5 GO:0015816 glycine transport(GO:0015816)
0.3 0.9 GO:0036166 phenotypic switching(GO:0036166)
0.3 1.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 1.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 2.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3 2.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.3 4.1 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.3 6.0 GO:0006270 DNA replication initiation(GO:0006270)
0.3 6.2 GO:0006825 copper ion transport(GO:0006825)
0.3 0.8 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.3 1.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 5.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 3.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 0.3 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.3 6.3 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.3 1.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.3 5.0 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 13.9 GO:0048538 thymus development(GO:0048538)
0.3 1.6 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.3 2.3 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.3 3.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 4.1 GO:0060065 uterus development(GO:0060065)
0.3 1.5 GO:0015817 histidine transport(GO:0015817)
0.3 3.6 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.3 1.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 6.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 4.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.3 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 2.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.2 1.5 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 4.1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.2 1.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 9.1 GO:0000266 mitochondrial fission(GO:0000266)
0.2 4.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 5.4 GO:0042168 heme metabolic process(GO:0042168)
0.2 3.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.2 1.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 2.8 GO:0051601 exocyst localization(GO:0051601)
0.2 2.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 2.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 2.1 GO:0055070 copper ion homeostasis(GO:0055070)
0.2 1.8 GO:1990403 embryonic brain development(GO:1990403)
0.2 2.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 7.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 1.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 2.3 GO:0046686 response to cadmium ion(GO:0046686)
0.2 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 1.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 5.9 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.2 1.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.2 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 1.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.2 10.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 1.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 3.0 GO:0016486 peptide hormone processing(GO:0016486)
0.2 2.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 1.1 GO:0090383 phagosome acidification(GO:0090383)
0.2 3.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.2 4.0 GO:0016180 snRNA processing(GO:0016180)
0.2 22.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.2 0.9 GO:0048318 axial mesoderm development(GO:0048318)
0.2 1.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 0.9 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2 2.1 GO:0016926 protein desumoylation(GO:0016926)
0.2 1.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 1.9 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 0.7 GO:0071475 cellular hyperosmotic salinity response(GO:0071475) cellular response to X-ray(GO:0071481)
0.2 2.5 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.2 2.3 GO:0006999 nuclear pore organization(GO:0006999)
0.2 1.0 GO:1903867 chorion development(GO:0060717) extraembryonic membrane development(GO:1903867)
0.2 0.5 GO:0016598 protein arginylation(GO:0016598)
0.2 2.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.2 4.4 GO:0018345 protein palmitoylation(GO:0018345)
0.2 0.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 4.7 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.2 1.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 1.1 GO:0071318 cellular response to ATP(GO:0071318)
0.2 4.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 1.7 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.2 0.6 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 5.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.2 4.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.2 2.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 2.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 7.5 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.1 1.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 2.1 GO:0042407 cristae formation(GO:0042407)
0.1 2.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.7 GO:0009650 UV protection(GO:0009650)
0.1 1.0 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.1 1.4 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 1.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 1.6 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.9 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.3 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 1.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.3 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 1.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 14.1 GO:0031109 microtubule polymerization or depolymerization(GO:0031109)
0.1 1.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 1.7 GO:0010388 protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388)
0.1 0.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 1.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.8 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 8.5 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.1 6.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.7 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 1.5 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 2.2 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 0.6 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 1.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.3 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 1.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.7 GO:0022900 electron transport chain(GO:0022900)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 6.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 2.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.7 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.8 GO:0001996 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993) positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.1 0.3 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.1 2.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.4 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 5.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 3.8 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 2.5 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 1.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.7 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 1.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 2.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.7 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.1 1.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.6 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.1 2.5 GO:0043039 tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
0.1 1.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 1.5 GO:0030336 negative regulation of cell migration(GO:0030336) negative regulation of cell motility(GO:2000146)
0.1 0.9 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 1.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 4.2 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.7 GO:0021554 optic nerve development(GO:0021554)
0.1 2.0 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1 2.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 3.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 3.3 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1 1.5 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 3.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 3.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 3.3 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.9 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.5 GO:0002507 tolerance induction(GO:0002507)
0.1 1.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 3.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.4 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.5 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:0098656 anion transmembrane transport(GO:0098656)
0.1 6.3 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.1 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.4 GO:0045056 transcytosis(GO:0045056)
0.1 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.6 GO:0001895 retina homeostasis(GO:0001895)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.4 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.4 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 1.3 GO:0006006 glucose metabolic process(GO:0006006)
0.0 1.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 1.8 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.4 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 2.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 5.0 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 2.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 1.1 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0045333 cellular respiration(GO:0045333)
0.0 0.4 GO:0003229 ventricular cardiac muscle tissue development(GO:0003229)
0.0 1.3 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836) positive regulation of protein depolymerization(GO:1901881)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.0 0.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 26.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.8 8.3 GO:1990393 3M complex(GO:1990393)
2.7 8.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
2.6 7.8 GO:0071821 FANCM-MHF complex(GO:0071821)
2.3 16.3 GO:0001940 male pronucleus(GO:0001940)
1.8 7.2 GO:0032021 NELF complex(GO:0032021)
1.7 5.0 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.6 4.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.6 6.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.6 7.8 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.5 24.8 GO:0005652 nuclear lamina(GO:0005652)
1.4 11.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.4 4.3 GO:1990047 spindle matrix(GO:1990047)
1.3 4.0 GO:0071914 prominosome(GO:0071914)
1.3 6.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.3 21.1 GO:0031616 spindle pole centrosome(GO:0031616)
1.1 2.3 GO:0070557 PCNA-p21 complex(GO:0070557)
1.1 11.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.1 3.2 GO:0000811 GINS complex(GO:0000811)
1.0 3.1 GO:0000814 ESCRT II complex(GO:0000814)
0.9 4.7 GO:0044316 cone cell pedicle(GO:0044316)
0.9 3.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.9 5.4 GO:0000235 astral microtubule(GO:0000235)
0.9 5.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.9 2.7 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.9 7.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.9 6.9 GO:0033269 internode region of axon(GO:0033269)
0.8 8.0 GO:0042575 DNA polymerase complex(GO:0042575)
0.8 10.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.7 9.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.7 3.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.7 1.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.7 6.3 GO:0000439 core TFIIH complex(GO:0000439)
0.7 8.4 GO:0031105 septin complex(GO:0031105)
0.7 8.9 GO:0032797 SMN complex(GO:0032797)
0.7 5.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.7 2.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.7 4.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.7 32.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.6 3.9 GO:0033010 paranodal junction(GO:0033010)
0.6 1.9 GO:1990879 CST complex(GO:1990879)
0.6 3.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.6 5.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.6 43.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.6 3.6 GO:0005796 Golgi lumen(GO:0005796)
0.6 8.3 GO:0031528 microvillus membrane(GO:0031528)
0.6 8.3 GO:0042555 MCM complex(GO:0042555)
0.6 6.4 GO:0070938 contractile ring(GO:0070938)
0.6 2.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.6 1.7 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.6 6.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.5 7.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 2.7 GO:0008623 CHRAC(GO:0008623)
0.5 2.1 GO:0005745 m-AAA complex(GO:0005745)
0.5 2.5 GO:0005861 troponin complex(GO:0005861)
0.5 2.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.5 40.8 GO:0005643 nuclear pore(GO:0005643)
0.5 7.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.5 6.7 GO:0000974 Prp19 complex(GO:0000974)
0.5 1.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.5 3.3 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.5 12.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.5 1.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.5 3.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.5 6.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 2.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.7 GO:0001533 cornified envelope(GO:0001533)
0.4 4.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 5.8 GO:0043218 compact myelin(GO:0043218)
0.4 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.4 1.8 GO:0090543 Flemming body(GO:0090543)
0.4 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.3 1.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.3 1.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 3.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 3.0 GO:0000243 commitment complex(GO:0000243)
0.3 13.8 GO:0034707 chloride channel complex(GO:0034707)
0.3 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 5.3 GO:0030686 90S preribosome(GO:0030686)
0.3 2.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 4.5 GO:0031527 filopodium membrane(GO:0031527)
0.3 2.1 GO:0070187 telosome(GO:0070187)
0.3 0.9 GO:0034455 t-UTP complex(GO:0034455)
0.3 2.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 5.2 GO:0005686 U2 snRNP(GO:0005686)
0.3 16.1 GO:0005871 kinesin complex(GO:0005871)
0.3 4.0 GO:0032039 integrator complex(GO:0032039)
0.3 2.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 2.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 4.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 3.1 GO:0005688 U6 snRNP(GO:0005688)
0.3 0.5 GO:0098576 lumenal side of membrane(GO:0098576)
0.3 1.1 GO:0030894 replisome(GO:0030894)
0.3 2.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.3 12.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 8.0 GO:0015030 Cajal body(GO:0015030)
0.2 1.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 1.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 9.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 1.4 GO:0070847 core mediator complex(GO:0070847)
0.2 1.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 2.1 GO:0061617 MICOS complex(GO:0061617)
0.2 2.0 GO:0000815 ESCRT III complex(GO:0000815)
0.2 8.8 GO:1990204 oxidoreductase complex(GO:1990204)
0.2 1.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 3.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 1.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 15.0 GO:0005581 collagen trimer(GO:0005581)
0.2 9.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 1.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 3.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 0.6 GO:0031415 NatA complex(GO:0031415)
0.2 0.6 GO:0097447 dendritic tree(GO:0097447)
0.2 1.9 GO:0070069 cytochrome complex(GO:0070069)
0.2 13.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 1.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 2.1 GO:0043596 nuclear replication fork(GO:0043596)
0.2 8.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 5.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 5.0 GO:0097223 sperm part(GO:0097223)
0.2 3.3 GO:0030684 preribosome(GO:0030684)
0.2 1.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 1.5 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.5 GO:0000801 central element(GO:0000801)
0.2 5.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 1.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 12.6 GO:0005840 ribosome(GO:0005840)
0.1 8.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.8 GO:0071564 npBAF complex(GO:0071564)
0.1 8.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 4.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 1.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 14.1 GO:0005903 brush border(GO:0005903)
0.1 9.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.9 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 2.4 GO:0030914 STAGA complex(GO:0030914)
0.1 0.6 GO:0000502 proteasome complex(GO:0000502)
0.1 2.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.9 GO:0031143 pseudopodium(GO:0031143)
0.1 1.2 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.0 GO:0046930 pore complex(GO:0046930) Bcl-2 family protein complex(GO:0097136)
0.1 6.4 GO:0016459 myosin complex(GO:0016459)
0.1 7.1 GO:0005811 lipid particle(GO:0005811)
0.1 0.7 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 1.2 GO:0016235 aggresome(GO:0016235)
0.1 1.6 GO:0070469 respiratory chain(GO:0070469)
0.1 1.3 GO:0033202 DNA helicase complex(GO:0033202)
0.1 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 7.8 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 2.3 GO:0005921 gap junction(GO:0005921)
0.1 2.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.6 GO:0090544 BAF-type complex(GO:0090544)
0.1 15.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.2 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.3 GO:0005869 dynactin complex(GO:0005869)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 1.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 3.6 GO:0014704 intercalated disc(GO:0014704)
0.1 7.8 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 7.2 GO:0000776 kinetochore(GO:0000776)
0.1 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 5.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.9 GO:0000145 exocyst(GO:0000145)
0.1 2.2 GO:0005902 microvillus(GO:0005902)
0.1 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.3 GO:0070852 cell body fiber(GO:0070852)
0.1 2.0 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 4.4 GO:0005814 centriole(GO:0005814)
0.1 5.5 GO:0005819 spindle(GO:0005819)
0.0 8.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 1.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 12.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0010008 endosome membrane(GO:0010008)
0.0 1.2 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 1.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.1 GO:0030904 retromer complex(GO:0030904)
0.0 1.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 11.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 65.0 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
4.6 13.7 GO:0070905 serine binding(GO:0070905)
3.5 13.8 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
2.8 22.0 GO:0003688 DNA replication origin binding(GO:0003688)
2.7 8.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
2.5 14.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
2.4 7.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
2.1 2.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
1.9 7.8 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.9 5.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.9 7.5 GO:0016842 amidine-lyase activity(GO:0016842)
1.8 7.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.8 8.9 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.7 5.1 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
1.6 4.8 GO:0044388 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) small protein activating enzyme binding(GO:0044388) cupric ion binding(GO:1903135) cuprous ion binding(GO:1903136) glyoxalase (glycolic acid-forming) activity(GO:1990422)
1.6 12.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
1.6 6.3 GO:0042015 interleukin-20 binding(GO:0042015)
1.6 4.7 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.5 4.6 GO:0034618 arginine binding(GO:0034618)
1.5 4.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
1.5 6.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.4 4.3 GO:0030620 U2 snRNA binding(GO:0030620)
1.4 6.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
1.3 3.9 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
1.3 6.4 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.2 5.0 GO:0050436 microfibril binding(GO:0050436)
1.2 4.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.2 8.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.2 15.3 GO:0008301 DNA binding, bending(GO:0008301)
1.1 4.5 GO:0035877 death effector domain binding(GO:0035877)
1.1 12.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.1 31.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
1.1 9.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.1 11.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.1 11.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0 5.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.0 3.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
1.0 2.9 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.9 3.8 GO:0019808 polyamine binding(GO:0019808)
0.9 6.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.9 3.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.9 12.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.9 4.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.9 3.6 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.9 13.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.9 6.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.8 4.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.8 2.5 GO:0030172 troponin C binding(GO:0030172)
0.8 2.4 GO:0004560 alpha-L-fucosidase activity(GO:0004560)
0.8 2.4 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.8 2.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.8 11.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.8 3.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.7 6.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.7 10.9 GO:0016805 dipeptidase activity(GO:0016805)
0.7 32.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.7 2.8 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.7 3.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7 5.4 GO:0035184 histone threonine kinase activity(GO:0035184)
0.7 2.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.7 1.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.7 4.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.6 7.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.6 5.0 GO:0008097 5S rRNA binding(GO:0008097)
0.6 6.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.6 1.8 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.6 8.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 4.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.6 2.3 GO:1990932 5.8S rRNA binding(GO:1990932)
0.6 1.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 7.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.6 5.6 GO:0015266 protein channel activity(GO:0015266)
0.5 3.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.5 2.1 GO:0042731 PH domain binding(GO:0042731)
0.5 3.6 GO:0000150 recombinase activity(GO:0000150)
0.5 7.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.5 1.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 2.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.5 8.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.5 2.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.5 1.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.5 10.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 6.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.5 1.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.5 4.7 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.5 1.4 GO:0051870 methotrexate binding(GO:0051870)
0.5 4.1 GO:0015643 toxic substance binding(GO:0015643)
0.5 10.8 GO:0008432 JUN kinase binding(GO:0008432)
0.5 1.8 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.4 1.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.4 2.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.4 3.5 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.4 4.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.4 0.4 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.4 2.5 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.4 2.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.4 1.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.4 1.9 GO:0000403 Y-form DNA binding(GO:0000403)
0.4 1.5 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.4 4.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 3.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.4 4.3 GO:0036310 annealing helicase activity(GO:0036310)
0.4 6.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 5.8 GO:0070402 NADPH binding(GO:0070402)
0.4 0.7 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.4 2.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.4 1.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 5.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.4 1.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.4 4.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 3.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 2.8 GO:0008251 tRNA-specific adenosine deaminase activity(GO:0008251)
0.3 5.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 1.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 9.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 2.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 0.7 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 1.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.3 11.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 4.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 13.3 GO:0016504 peptidase activator activity(GO:0016504)
0.3 1.2 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.3 5.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 1.5 GO:0008494 translation activator activity(GO:0008494)
0.3 65.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 4.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 0.9 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 6.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 1.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.3 7.4 GO:0008198 ferrous iron binding(GO:0008198)
0.3 3.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 2.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 1.4 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.3 1.4 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.3 2.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 0.8 GO:0048039 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) ubiquinone binding(GO:0048039)
0.3 0.8 GO:0030362 protein phosphatase type 4 regulator activity(GO:0030362)
0.3 2.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 3.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 1.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 5.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 2.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 1.5 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.3 2.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 1.8 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.3 5.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.0 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.2 7.3 GO:0005112 Notch binding(GO:0005112)
0.2 2.9 GO:0008430 selenium binding(GO:0008430)
0.2 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 0.9 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.2 1.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 2.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 5.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 2.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 3.4 GO:0001848 complement binding(GO:0001848)
0.2 1.5 GO:0045703 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.2 1.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 1.3 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 1.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 8.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 3.5 GO:0032183 SUMO binding(GO:0032183)
0.2 0.6 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.2 1.4 GO:0030957 Tat protein binding(GO:0030957)
0.2 2.0 GO:0003680 AT DNA binding(GO:0003680)
0.2 2.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 3.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.9 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 3.6 GO:0043422 protein kinase B binding(GO:0043422)
0.2 1.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 2.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 7.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.2 4.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.2 3.2 GO:0071837 HMG box domain binding(GO:0071837)
0.2 3.0 GO:0017166 vinculin binding(GO:0017166)
0.2 2.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 7.7 GO:0070888 E-box binding(GO:0070888)
0.2 1.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 3.0 GO:0042165 neurotransmitter binding(GO:0042165)
0.2 3.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 0.8 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 1.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 4.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.2 0.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 1.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 3.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 2.3 GO:0016594 glycine binding(GO:0016594)
0.1 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 1.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 5.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 2.7 GO:0015923 mannosidase activity(GO:0015923)
0.1 4.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 3.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 4.6 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.9 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 3.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 6.0 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 0.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 1.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 6.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.8 GO:0005123 death receptor binding(GO:0005123)
0.1 12.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.9 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 3.3 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) DNA-N1-methyladenine dioxygenase activity(GO:0043734) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.1 3.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.0 GO:0048185 activin binding(GO:0048185)
0.1 4.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.5 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.1 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 3.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 4.5 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 4.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 3.5 GO:0002039 p53 binding(GO:0002039)
0.1 5.5 GO:0004386 helicase activity(GO:0004386)
0.1 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 2.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.3 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 9.8 GO:0051015 actin filament binding(GO:0051015)
0.1 1.0 GO:0017069 snRNA binding(GO:0017069)
0.1 0.6 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 15.7 GO:0005198 structural molecule activity(GO:0005198)
0.1 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181) metalloexopeptidase activity(GO:0008235)
0.1 1.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 52.0 GO:0044822 poly(A) RNA binding(GO:0044822)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 17.0 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 3.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 1.3 GO:0051287 NAD binding(GO:0051287)
0.0 4.0 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.8 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 2.0 GO:0042393 histone binding(GO:0042393)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 3.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 1.1 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0002020 protease binding(GO:0002020)
0.0 1.0 GO:0015399 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.4 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 1.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.1 GO:0003682 chromatin binding(GO:0003682)