Motif ID: Plagl1
Z-value: 0.553
Transcription factors associated with Plagl1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Plagl1 | ENSMUSG00000019817.12 | Plagl1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Plagl1 | mm10_v2_chr10_+_13090788_13090843 | -0.65 | 1.1e-09 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.2 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
1.0 | 10.3 | GO:0014824 | artery smooth muscle contraction(GO:0014824) |
0.8 | 3.8 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.5 | 2.4 | GO:0046684 | response to pyrethroid(GO:0046684) |
0.5 | 1.9 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.4 | 2.4 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.4 | 1.9 | GO:0001661 | conditioned taste aversion(GO:0001661) |
0.4 | 1.1 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.3 | 1.0 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
0.2 | 0.7 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
0.2 | 2.7 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.2 | 7.6 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.2 | 2.2 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
0.2 | 1.8 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.2 | 3.3 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.2 | 1.9 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
0.2 | 0.5 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
0.2 | 0.5 | GO:0097309 | cap1 mRNA methylation(GO:0097309) |
0.2 | 1.3 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.2 | 2.1 | GO:0043589 | skin morphogenesis(GO:0043589) |
0.2 | 1.4 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.1 | 0.4 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.1 | 1.0 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.1 | 1.5 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.1 | 1.2 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.1 | 1.0 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
0.1 | 3.9 | GO:0071625 | vocalization behavior(GO:0071625) |
0.1 | 2.3 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
0.1 | 2.3 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.1 | 0.3 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
0.1 | 0.5 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
0.1 | 0.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.1 | 2.3 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
0.1 | 0.7 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.1 | 0.6 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.1 | 0.4 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
0.1 | 0.4 | GO:0030091 | protein repair(GO:0030091) |
0.1 | 1.4 | GO:0032402 | melanosome transport(GO:0032402) |
0.0 | 0.3 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
0.0 | 0.2 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 0.5 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.0 | 4.7 | GO:0098792 | xenophagy(GO:0098792) |
0.0 | 0.9 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.0 | 1.8 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 1.1 | GO:0070542 | response to fatty acid(GO:0070542) |
0.0 | 0.3 | GO:0031639 | plasminogen activation(GO:0031639) |
0.0 | 1.3 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
0.0 | 0.3 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 1.5 | GO:0043388 | positive regulation of DNA binding(GO:0043388) |
0.0 | 0.6 | GO:0046834 | lipid phosphorylation(GO:0046834) |
0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.0 | 0.2 | GO:0006825 | copper ion transport(GO:0006825) |
0.0 | 2.8 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 1.4 | GO:0055072 | iron ion homeostasis(GO:0055072) |
0.0 | 0.4 | GO:0035455 | response to interferon-alpha(GO:0035455) |
0.0 | 0.2 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.0 | 0.7 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
0.0 | 0.3 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.0 | 0.1 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
0.0 | 0.5 | GO:0008333 | endosome to lysosome transport(GO:0008333) early endosome to late endosome transport(GO:0045022) |
0.0 | 0.8 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 0.3 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.1 | GO:0005584 | collagen type I trimer(GO:0005584) |
0.4 | 2.3 | GO:0008091 | spectrin(GO:0008091) |
0.3 | 1.9 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.2 | 1.0 | GO:0071797 | LUBAC complex(GO:0071797) |
0.2 | 1.9 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.2 | 4.6 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.2 | 2.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 2.4 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.1 | 1.3 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 3.8 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.1 | 0.4 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
0.1 | 1.4 | GO:0005869 | dynactin complex(GO:0005869) |
0.1 | 10.3 | GO:0043198 | dendritic shaft(GO:0043198) |
0.1 | 5.9 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 2.7 | GO:0032420 | stereocilium(GO:0032420) |
0.1 | 1.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 0.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.1 | 0.5 | GO:0098533 | ATPase dependent transmembrane transport complex(GO:0098533) |
0.0 | 1.8 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.9 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 2.2 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 1.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 2.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 1.7 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 0.7 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.0 | 1.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.7 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.3 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 1.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.5 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.2 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.7 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 1.5 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.3 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.4 | GO:0035861 | site of double-strand break(GO:0035861) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.2 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.6 | 1.9 | GO:0070905 | serine binding(GO:0070905) |
0.5 | 2.3 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.4 | 1.5 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.3 | 0.3 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.3 | 1.1 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
0.2 | 0.7 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.2 | 2.7 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.2 | 1.9 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.2 | 1.8 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.2 | 1.0 | GO:0071253 | connexin binding(GO:0071253) |
0.2 | 1.4 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.1 | 10.3 | GO:0035254 | glutamate receptor binding(GO:0035254) |
0.1 | 2.1 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 2.9 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.1 | 0.5 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
0.1 | 2.4 | GO:0031402 | sodium ion binding(GO:0031402) |
0.1 | 2.5 | GO:0048156 | tau protein binding(GO:0048156) |
0.1 | 2.3 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
0.1 | 0.3 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
0.1 | 0.6 | GO:0001727 | lipid kinase activity(GO:0001727) |
0.1 | 0.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.1 | 0.5 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.1 | 3.8 | GO:0035064 | methylated histone binding(GO:0035064) |
0.1 | 0.4 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
0.0 | 0.5 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
0.0 | 0.3 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
0.0 | 2.0 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.7 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.2 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.0 | 1.4 | GO:0045502 | dynein binding(GO:0045502) |
0.0 | 1.3 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 0.8 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 2.4 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.1 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
0.0 | 0.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.0 | 0.4 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.3 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 1.0 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 1.6 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492) |
0.0 | 0.2 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.0 | 1.0 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 7.6 | GO:0005198 | structural molecule activity(GO:0005198) |
0.0 | 1.9 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.2 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
0.0 | 0.7 | GO:0005262 | calcium channel activity(GO:0005262) |
0.0 | 0.3 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.0 | 1.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 5.0 | GO:0005509 | calcium ion binding(GO:0005509) |