Motif ID: Pou2f2_Pou3f1

Z-value: 1.964

Transcription factors associated with Pou2f2_Pou3f1:

Gene SymbolEntrez IDGene Name
Pou2f2 ENSMUSG00000008496.12 Pou2f2
Pou3f1 ENSMUSG00000090125.2 Pou3f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f1mm10_v2_chr4_+_124657646_124657656-0.474.6e-05Click!
Pou2f2mm10_v2_chr7_-_25132473_25132512-0.353.0e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_45017953 27.345 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr6_+_8949670 20.477 ENSMUST00000060369.3
Nxph1
neurexophilin 1
chr2_+_25180737 18.451 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr6_-_67037399 17.515 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr12_+_89812467 17.196 ENSMUST00000110133.2
ENSMUST00000110130.2
Nrxn3

neurexin III

chr14_+_67234620 16.828 ENSMUST00000176029.1
Ebf2
early B cell factor 2
chr17_-_58991343 14.560 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr2_-_36105271 14.025 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr2_+_105675478 14.019 ENSMUST00000167211.2
ENSMUST00000111083.3
Pax6

paired box gene 6

chr13_-_56252163 13.942 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr2_+_105675429 13.566 ENSMUST00000111085.1
Pax6
paired box gene 6
chr2_+_71528657 12.217 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr13_+_23746734 12.000 ENSMUST00000099703.2
Hist1h2bb
histone cluster 1, H2bb
chr2_+_103566304 11.870 ENSMUST00000076212.3
Abtb2
ankyrin repeat and BTB (POZ) domain containing 2
chr13_+_23751069 11.485 ENSMUST00000078369.1
Hist1h2ab
histone cluster 1, H2ab
chr8_+_12395287 11.453 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr13_+_23684192 11.179 ENSMUST00000018246.4
Hist1h2bc
histone cluster 1, H2bc
chr13_-_23571151 11.102 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chr2_+_172549581 10.921 ENSMUST00000030391.2
Tfap2c
transcription factor AP-2, gamma
chr13_-_21833575 10.829 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 78.5 GO:0006342 chromatin silencing(GO:0006342)
2.4 29.4 GO:0002227 innate immune response in mucosa(GO:0002227)
2.0 29.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.3 28.5 GO:0006334 nucleosome assembly(GO:0006334)
5.5 27.6 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
2.1 27.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.6 27.3 GO:0060325 face morphogenesis(GO:0060325)
0.8 25.2 GO:0007638 mechanosensory behavior(GO:0007638)
1.2 19.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
2.3 18.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 18.0 GO:0007067 mitotic nuclear division(GO:0007067)
0.5 17.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
1.1 16.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
2.6 15.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.1 15.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
2.0 13.9 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
4.5 13.5 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
4.1 12.2 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.8 11.9 GO:0097237 cellular response to toxic substance(GO:0097237)
0.9 11.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 107.5 GO:0005634 nucleus(GO:0005634)
0.2 85.2 GO:0000790 nuclear chromatin(GO:0000790)
1.8 60.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 39.9 GO:0005912 adherens junction(GO:0005912)
0.6 27.0 GO:0000786 nucleosome(GO:0000786)
0.1 22.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
5.0 19.8 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 19.2 GO:0001669 acrosomal vesicle(GO:0001669)
1.7 16.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 16.6 GO:0017053 transcriptional repressor complex(GO:0017053)
3.0 14.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 13.3 GO:0042734 presynaptic membrane(GO:0042734)
0.2 11.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.6 11.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.8 10.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 9.9 GO:0043204 perikaryon(GO:0043204)
0.1 9.3 GO:0016605 PML body(GO:0016605)
0.6 9.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 9.0 GO:0016604 nuclear body(GO:0016604)
1.0 7.8 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 165.8 GO:0003677 DNA binding(GO:0003677)
0.3 76.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
2.5 27.6 GO:0003680 AT DNA binding(GO:0003680)
0.4 27.3 GO:0019003 GDP binding(GO:0019003)
0.4 19.0 GO:0070888 E-box binding(GO:0070888)
0.2 18.5 GO:0001047 core promoter binding(GO:0001047)
1.6 17.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 15.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 15.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 14.7 GO:0051015 actin filament binding(GO:0051015)
1.3 11.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 11.0 GO:0004407 histone deacetylase activity(GO:0004407)
1.3 10.7 GO:0061133 endopeptidase activator activity(GO:0061133)
2.5 10.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 10.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.3 9.6 GO:0005112 Notch binding(GO:0005112)
0.8 8.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 8.1 GO:0005096 GTPase activator activity(GO:0005096)
0.9 7.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.3 7.6 GO:0070644 vitamin D response element binding(GO:0070644)