Motif ID: Pou3f2
Z-value: 0.747
Transcription factors associated with Pou3f2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou3f2 | ENSMUSG00000095139.1 | Pou3f2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou3f2 | mm10_v2_chr4_-_22488296_22488366 | 0.30 | 1.1e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.6 | 19.9 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
2.3 | 9.4 | GO:0042938 | dipeptide transport(GO:0042938) |
1.1 | 3.2 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
1.0 | 5.7 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
1.0 | 2.9 | GO:1902336 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) |
0.9 | 3.8 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
0.9 | 2.7 | GO:1905065 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
0.8 | 5.6 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.7 | 6.4 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
0.6 | 1.8 | GO:0032240 | RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
0.5 | 4.3 | GO:0090166 | Golgi disassembly(GO:0090166) |
0.5 | 3.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.4 | 3.1 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
0.4 | 1.3 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
0.4 | 2.4 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.4 | 5.3 | GO:0072010 | renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
0.3 | 1.3 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.3 | 1.3 | GO:0032512 | regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.2 | 4.1 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
0.2 | 0.9 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.2 | 1.9 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
0.2 | 4.7 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.2 | 1.7 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.2 | 1.4 | GO:0002674 | negative regulation of acute inflammatory response(GO:0002674) |
0.2 | 3.9 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
0.2 | 1.5 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
0.2 | 0.5 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.1 | 14.3 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
0.1 | 0.5 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.1 | 0.9 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.1 | 1.3 | GO:0015825 | L-serine transport(GO:0015825) |
0.1 | 0.4 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
0.1 | 0.5 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.1 | 0.8 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.1 | 1.3 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.1 | 3.1 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
0.1 | 0.9 | GO:0042640 | anagen(GO:0042640) |
0.1 | 0.7 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.1 | 0.4 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
0.1 | 0.2 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.1 | 2.2 | GO:0046677 | response to antibiotic(GO:0046677) |
0.1 | 0.6 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.1 | 2.0 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
0.1 | 4.5 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 2.9 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
0.0 | 1.3 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
0.0 | 1.0 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
0.0 | 0.1 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
0.0 | 0.7 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.0 | 4.0 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
0.0 | 1.5 | GO:0007292 | female gamete generation(GO:0007292) |
0.0 | 0.1 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.0 | 0.1 | GO:0006046 | N-acetylglucosamine catabolic process(GO:0006046) |
0.0 | 1.0 | GO:0007338 | single fertilization(GO:0007338) |
0.0 | 0.6 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
0.0 | 0.3 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 6.1 | GO:0001940 | male pronucleus(GO:0001940) |
0.6 | 5.7 | GO:0005642 | annulate lamellae(GO:0005642) |
0.5 | 1.8 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.5 | 4.1 | GO:0072687 | meiotic spindle(GO:0072687) |
0.4 | 6.1 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.4 | 1.5 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.3 | 4.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.2 | 0.4 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.1 | 1.0 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.1 | 1.3 | GO:0005916 | fascia adherens(GO:0005916) |
0.1 | 4.0 | GO:0043034 | costamere(GO:0043034) |
0.1 | 3.1 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.1 | 1.5 | GO:0042555 | MCM complex(GO:0042555) |
0.1 | 21.2 | GO:0031965 | nuclear membrane(GO:0031965) |
0.1 | 3.8 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 3.9 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.1 | 4.3 | GO:0005876 | spindle microtubule(GO:0005876) |
0.1 | 0.9 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 3.8 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 0.7 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 0.9 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 3.1 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 3.1 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 4.7 | GO:0005875 | microtubule associated complex(GO:0005875) |
0.0 | 2.4 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.2 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.0 | 2.9 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.9 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.2 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.9 | GO:0005635 | nuclear envelope(GO:0005635) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.6 | 19.9 | GO:0004962 | endothelin receptor activity(GO:0004962) |
1.9 | 9.4 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
1.3 | 3.8 | GO:0043532 | angiostatin binding(GO:0043532) |
1.0 | 2.9 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.8 | 3.2 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.7 | 5.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.6 | 8.2 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.4 | 3.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.4 | 2.0 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.4 | 2.7 | GO:0052650 | retinal binding(GO:0016918) NADP-retinol dehydrogenase activity(GO:0052650) |
0.4 | 1.8 | GO:0070840 | dynein complex binding(GO:0070840) |
0.3 | 2.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.3 | 1.3 | GO:0071253 | connexin binding(GO:0071253) |
0.2 | 1.4 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.2 | 4.3 | GO:0035173 | histone kinase activity(GO:0035173) |
0.2 | 5.7 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.2 | 3.9 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.2 | 1.3 | GO:0043495 | protein anchor(GO:0043495) |
0.2 | 0.5 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.1 | 1.3 | GO:0038191 | neuropilin binding(GO:0038191) |
0.1 | 6.4 | GO:0070888 | E-box binding(GO:0070888) |
0.1 | 2.4 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.1 | 0.5 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.1 | 4.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 0.9 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
0.1 | 0.4 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
0.1 | 1.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.1 | 1.8 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
0.1 | 0.7 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.1 | 4.7 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.1 | 0.5 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.9 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 0.2 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.0 | 0.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.0 | 4.0 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 4.2 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 3.7 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
0.0 | 1.5 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.4 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.7 | GO:0051287 | NAD binding(GO:0051287) |
0.0 | 7.0 | GO:0019901 | protein kinase binding(GO:0019901) |