Motif ID: Pou3f4
Z-value: 0.635
Transcription factors associated with Pou3f4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Pou3f4 | ENSMUSG00000056854.3 | Pou3f4 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pou3f4 | mm10_v2_chrX_+_110814390_110814413 | 0.21 | 8.7e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 13.9 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 1.4 | 4.2 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 1.4 | 4.1 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 1.1 | 3.2 | GO:1904395 | regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.9 | 7.4 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.9 | 6.4 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 0.5 | 4.2 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.5 | 4.7 | GO:0021984 | adenohypophysis development(GO:0021984) |
| 0.5 | 2.1 | GO:1904192 | prostate gland stromal morphogenesis(GO:0060741) cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193) |
| 0.5 | 1.4 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.4 | 3.7 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.4 | 1.2 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.4 | 5.6 | GO:1902993 | positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993) |
| 0.3 | 1.0 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.3 | 3.9 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.3 | 1.2 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.3 | 4.0 | GO:0051764 | actin crosslink formation(GO:0051764) positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.3 | 1.6 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.3 | 0.8 | GO:0048388 | endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401) |
| 0.2 | 2.1 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.2 | 0.7 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 0.2 | 0.9 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.2 | 1.7 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 1.9 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.2 | 1.1 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.2 | 0.9 | GO:0098700 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 0.1 | 0.7 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.1 | 1.0 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.1 | 2.8 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.1 | 1.0 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.1 | 1.8 | GO:0001553 | luteinization(GO:0001553) |
| 0.1 | 0.4 | GO:0061010 | gall bladder development(GO:0061010) |
| 0.1 | 6.2 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
| 0.1 | 0.4 | GO:1900242 | regulation of synaptic vesicle endocytosis(GO:1900242) |
| 0.1 | 0.1 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.1 | 0.5 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
| 0.1 | 1.3 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.1 | 0.6 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.1 | 0.5 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.1 | 0.1 | GO:0071726 | response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
| 0.1 | 0.3 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.0 | 0.4 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.0 | 1.3 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.6 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.0 | 0.8 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.0 | 0.3 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.0 | 0.9 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 1.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 0.1 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.0 | 0.9 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 0.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.4 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.4 | GO:0007614 | short-term memory(GO:0007614) |
| 0.0 | 0.5 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 2.1 | GO:0009636 | response to toxic substance(GO:0009636) |
| 0.0 | 0.6 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
| 0.0 | 0.1 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.0 | 0.1 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.0 | 0.0 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.1 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.8 | 7.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.5 | 2.1 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
| 0.4 | 4.0 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.3 | 2.1 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.3 | 3.8 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.2 | 1.0 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.1 | 1.2 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 0.5 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
| 0.1 | 0.6 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 2.8 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 0.4 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 8.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 0.8 | GO:0042581 | specific granule(GO:0042581) |
| 0.1 | 0.6 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.0 | 0.6 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 0.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 3.2 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 2.6 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 8.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 6.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.1 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.0 | 0.4 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.1 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 4.2 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.1 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.0 | 5.5 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.7 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
| 1.1 | 3.2 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 1.0 | 4.2 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.6 | 2.8 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.5 | 1.4 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
| 0.4 | 1.6 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.3 | 4.2 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.3 | 2.1 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.3 | 7.4 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.3 | 4.1 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.3 | 1.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.2 | 1.4 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 0.2 | 0.9 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
| 0.2 | 1.5 | GO:0052650 | retinal binding(GO:0016918) NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.2 | 0.8 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.2 | 1.2 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 0.2 | 2.8 | GO:0008430 | selenium binding(GO:0008430) |
| 0.2 | 0.9 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 4.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 1.7 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 2.1 | GO:0043539 | insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 0.3 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.1 | 3.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 1.2 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.1 | 0.4 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.1 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.5 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
| 0.0 | 0.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.6 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.0 | 3.4 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 6.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.9 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 1.1 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.5 | GO:0052890 | oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890) |
| 0.0 | 0.7 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 8.6 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 3.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 1.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 2.1 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.0 | 0.9 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.6 | GO:0031593 | polyubiquitin binding(GO:0031593) |
