Motif ID: Pou3f4

Z-value: 0.635


Transcription factors associated with Pou3f4:

Gene SymbolEntrez IDGene Name
Pou3f4 ENSMUSG00000056854.3 Pou3f4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f4mm10_v2_chrX_+_110814390_1108144130.218.7e-02Click!


Activity profile for motif Pou3f4.

activity profile for motif Pou3f4


Sorted Z-values histogram for motif Pou3f4

Sorted Z-values for motif Pou3f4



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f4

PNG image of the network

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Top targets:


Showing 1 to 20 of 125 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22439570 7.069 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr16_-_22439719 6.836 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr15_+_92161343 6.238 ENSMUST00000068378.5
 Cntn1
contactin 1
chr7_+_113765998 5.191 ENSMUST00000046687.9
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr17_-_58991343 4.829 ENSMUST00000025064.7
 2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr5_+_147188678 4.672 ENSMUST00000065382.5
 Gsx1
GS homeobox 1
chr18_+_56432116 4.224 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr18_-_74961252 4.175 ENSMUST00000066532.4
 Lipg
lipase, endothelial
chr1_+_159737510 4.113 ENSMUST00000111669.3
 Tnr
tenascin R
chr15_-_79285502 3.997 ENSMUST00000165408.1
 Baiap2l2
BAI1-associated protein 2-like 2
chr10_+_90576252 3.871 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
 Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr7_+_87803815 3.685 ENSMUST00000125009.1
ENSMUST00000155358.1
 Grm5

glutamate receptor, metabotropic 5

chr3_+_68869563 3.673 ENSMUST00000054551.2
 1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr3_-_57575907 3.245 ENSMUST00000120977.1
 Wwtr1
WW domain containing transcription regulator 1
chr6_-_36811361 3.231 ENSMUST00000101534.1
 Ptn
pleiotrophin
chr10_-_64090241 3.135 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr3_-_57575760 3.107 ENSMUST00000029380.7
 Wwtr1
WW domain containing transcription regulator 1
chr19_+_55741810 2.891 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr6_+_21215472 2.772 ENSMUST00000081542.5
 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr10_-_64090265 2.447 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 13.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.9 7.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.9 6.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 6.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.4 5.6 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.5 4.7 GO:0021984 adenohypophysis development(GO:0021984)
1.4 4.2 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.5 4.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.4 4.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.3 4.0 GO:0051764 actin crosslink formation(GO:0051764) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 3.9 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4 3.7 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.1 3.2 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 2.8 GO:0045475 locomotor rhythm(GO:0045475)
0.5 2.1 GO:1904192 prostate gland stromal morphogenesis(GO:0060741) cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.2 2.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 2.1 GO:0009636 response to toxic substance(GO:0009636)
0.2 1.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.8 GO:0001553 luteinization(GO:0001553)
0.2 1.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 8.0 GO:0031225 anchored component of membrane(GO:0031225)
0.8 7.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 6.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 5.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.2 GO:0005769 early endosome(GO:0005769)
1.4 4.1 GO:0072534 perineuronal net(GO:0072534)
0.4 4.0 GO:0071439 clathrin complex(GO:0071439)
0.3 3.8 GO:0097449 astrocyte projection(GO:0097449)
0.0 3.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.5 2.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.3 2.1 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.0 GO:0097227 sperm annulus(GO:0097227)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.8 GO:0042581 specific granule(GO:0042581)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 7.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 6.2 GO:0030246 carbohydrate binding(GO:0030246)
1.0 4.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 4.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.3 4.1 GO:0046625 sphingolipid binding(GO:0046625)
0.1 4.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 3.8 GO:0003714 transcription corepressor activity(GO:0003714)
1.2 3.7 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 3.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
1.1 3.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.6 2.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 2.8 GO:0008430 selenium binding(GO:0008430)
0.3 2.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 2.1 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.1 GO:0003774 motor activity(GO:0003774)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 1.6 GO:0004565 beta-galactosidase activity(GO:0004565)