Motif ID: Pou5f1

Z-value: 1.595


Transcription factors associated with Pou5f1:

Gene SymbolEntrez IDGene Name
Pou5f1 ENSMUSG00000024406.10 Pou5f1



Activity profile for motif Pou5f1.

activity profile for motif Pou5f1


Sorted Z-values histogram for motif Pou5f1

Sorted Z-values for motif Pou5f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou5f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 47.693 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr8_+_54954728 33.700 ENSMUST00000033915.7
 Gpm6a
glycoprotein m6a
chr6_-_55681257 30.442 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr3_-_80802789 27.321 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_+_97772734 26.325 ENSMUST00000152023.1
 Nfia
nuclear factor I/A
chr7_+_24507099 22.789 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr11_+_98741805 21.723 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr12_+_29528382 21.198 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr18_-_42899470 20.166 ENSMUST00000120632.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_-_42899294 19.910 ENSMUST00000117687.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr15_-_66831625 19.296 ENSMUST00000164163.1
 Sla
src-like adaptor
chr2_+_124610573 19.002 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr11_+_98741871 18.825 ENSMUST00000103139.4
 Thra
thyroid hormone receptor alpha
chr11_+_58954675 18.479 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chrX_-_165327376 16.122 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr8_-_33747724 16.053 ENSMUST00000179364.1
 Smim18
small integral membrane protein 18
chr17_-_90455872 15.968 ENSMUST00000174337.1
ENSMUST00000172466.1
 Nrxn1

neurexin I

chr1_+_177444653 15.321 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr8_+_118283719 15.174 ENSMUST00000117160.1
 Cdh13
cadherin 13
chr17_-_91092715 15.096 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 73.0 GO:0006342 chromatin silencing(GO:0006342)
3.2 45.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 44.8 GO:0031032 actomyosin structure organization(GO:0031032)
1.2 43.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
4.3 42.9 GO:0042118 endothelial cell activation(GO:0042118)
13.5 40.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
5.7 40.1 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.5 37.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.3 37.0 GO:0060074 synapse maturation(GO:0060074)
1.7 34.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
2.0 34.0 GO:0021542 dentate gyrus development(GO:0021542)
6.2 31.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
2.0 28.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
1.0 28.6 GO:0007616 long-term memory(GO:0007616)
1.6 23.9 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.7 19.0 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 18.0 GO:0006897 endocytosis(GO:0006897)
0.4 17.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
2.3 16.1 GO:0071361 cellular response to zinc ion(GO:0071294) cellular response to ethanol(GO:0071361)
3.8 15.2 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 40.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 38.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 33.4 GO:0005739 mitochondrion(GO:0005739)
0.5 30.7 GO:0042734 presynaptic membrane(GO:0042734)
1.5 29.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.7 29.3 GO:0032279 asymmetric synapse(GO:0032279)
4.8 28.6 GO:0044308 axonal spine(GO:0044308)
0.9 28.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 27.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 26.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.6 23.0 GO:0000786 nucleosome(GO:0000786)
0.1 22.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 18.8 GO:0000790 nuclear chromatin(GO:0000790)
0.4 16.1 GO:0034707 chloride channel complex(GO:0034707)
0.2 15.8 GO:0043195 terminal bouton(GO:0043195)
0.3 15.3 GO:0045171 intercellular bridge(GO:0045171)
0.2 15.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
2.1 14.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 14.1 GO:0005776 autophagosome(GO:0005776)
0.3 13.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.0 55.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
10.7 42.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
13.5 40.5 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
2.9 40.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.5 37.7 GO:0005262 calcium channel activity(GO:0005262)
2.6 31.1 GO:0097109 neuroligin family protein binding(GO:0097109)
2.2 28.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 19.9 GO:0003779 actin binding(GO:0003779)
0.4 19.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.7 19.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 18.7 GO:0030674 protein binding, bridging(GO:0030674)
5.4 16.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
3.0 15.2 GO:0055100 adiponectin binding(GO:0055100)
0.2 14.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.5 14.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.8 12.9 GO:0031402 sodium ion binding(GO:0031402)
4.1 12.3 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.3 12.1 GO:0017022 myosin binding(GO:0017022)
0.4 12.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.6 11.0 GO:0001222 transcription corepressor binding(GO:0001222)