Motif ID: Pou6f2_Pou4f2

Z-value: 0.738

Transcription factors associated with Pou6f2_Pou4f2:

Gene SymbolEntrez IDGene Name
Pou4f2 ENSMUSG00000031688.3 Pou4f2
Pou6f2 ENSMUSG00000009734.11 Pou6f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f2mm10_v2_chr8_-_78436640_784366490.405.4e-04Click!
Pou6f2mm10_v2_chr13_-_18382041_18382041-0.075.5e-01Click!


Activity profile for motif Pou6f2_Pou4f2.

activity profile for motif Pou6f2_Pou4f2


Sorted Z-values histogram for motif Pou6f2_Pou4f2

Sorted Z-values for motif Pou6f2_Pou4f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 100 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_56296551 11.629 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr18_-_31949571 7.718 ENSMUST00000064016.5
 Gpr17
G protein-coupled receptor 17
chr10_+_99263224 6.169 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr6_+_63255971 6.114 ENSMUST00000159561.1
ENSMUST00000095852.3
 Grid2

glutamate receptor, ionotropic, delta 2

chr1_+_153665666 5.910 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr13_-_81570640 5.613 ENSMUST00000109565.2
 Gpr98
G protein-coupled receptor 98
chr1_+_153665274 5.474 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr1_-_72874877 5.292 ENSMUST00000027377.8
 Igfbp5
insulin-like growth factor binding protein 5
chr12_-_56535047 5.068 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr4_-_58499398 5.003 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr14_+_27039001 4.808 ENSMUST00000035336.3
 Il17rd
interleukin 17 receptor D
chr2_+_109917639 4.700 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr7_-_49636847 4.143 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr1_+_153665587 4.126 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 4.030 ENSMUST00000147482.1
 Rgs8
regulator of G-protein signaling 8
chr6_+_88724828 3.706 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr2_+_71528657 3.560 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr17_-_49564262 3.331 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chr4_+_117849361 3.055 ENSMUST00000163288.1
 Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_+_172341197 3.021 ENSMUST00000056136.3
 Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 19.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
3.9 11.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.9 7.7 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
1.0 6.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 6.7 GO:0007638 mechanosensory behavior(GO:0007638)
2.1 6.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.4 6.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
2.0 6.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.8 5.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.7 5.1 GO:0021759 globus pallidus development(GO:0021759)
1.3 5.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.6 4.7 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 4.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 4.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 4.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.5 3.8 GO:0019532 oxalate transport(GO:0019532)
1.2 3.6 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
1.0 3.0 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 2.9 GO:0001553 luteinization(GO:0001553)
0.0 2.9 GO:0007368 determination of left/right symmetry(GO:0007368)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 19.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.4 6.7 GO:0043196 varicosity(GO:0043196)
0.0 6.4 GO:0005667 transcription factor complex(GO:0005667)
1.3 5.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 5.0 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 5.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 4.4 GO:0000792 heterochromatin(GO:0000792)
0.0 3.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 3.0 GO:0097449 astrocyte projection(GO:0097449)
0.1 2.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.3 GO:0002102 podosome(GO:0002102)
0.3 1.9 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 1.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 1.6 GO:0097542 ciliary tip(GO:0097542)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 1.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 0.4 GO:0033093 Weibel-Palade body(GO:0033093)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 24.1 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.5 19.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 11.6 GO:0008009 chemokine activity(GO:0008009)
0.6 6.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 6.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 6.1 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
1.0 5.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.7 5.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 5.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.8 5.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.6 4.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 4.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 3.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.3 3.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 3.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.0 3.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 2.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.5 2.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.4 2.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.6 1.9 GO:0008502 melatonin receptor activity(GO:0008502)