Motif ID: Ppara

Z-value: 2.290


Transcription factors associated with Ppara:

Gene SymbolEntrez IDGene Name
Ppara ENSMUSG00000022383.7 Ppara



Activity profile for motif Ppara.

activity profile for motif Ppara


Sorted Z-values histogram for motif Ppara

Sorted Z-values for motif Ppara



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppara

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_35910032 37.091 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
 Atat1




alpha tubulin acetyltransferase 1




chr12_+_61523889 33.872 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr17_-_35909626 31.210 ENSMUST00000141132.1
 Atat1
alpha tubulin acetyltransferase 1
chr3_+_95164306 29.437 ENSMUST00000107217.1
ENSMUST00000168321.1
 Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr15_-_66801577 29.072 ENSMUST00000168589.1
 Sla
src-like adaptor
chr13_-_9878998 26.816 ENSMUST00000063093.9
 Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr7_-_25005895 25.347 ENSMUST00000102858.3
ENSMUST00000080882.6
 Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr11_+_67586520 25.101 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr15_+_80091320 24.165 ENSMUST00000009728.6
ENSMUST00000009727.5
 Syngr1

synaptogyrin 1

chr11_-_42000532 23.326 ENSMUST00000070735.3
 Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr8_+_124793013 23.068 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr8_+_124793061 22.619 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr1_-_162478004 22.333 ENSMUST00000086074.5
ENSMUST00000070330.7
 Dnm3

dynamin 3

chr7_-_141429351 22.141 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
 Cend1


cell cycle exit and neuronal differentiation 1


chr7_-_141429433 21.774 ENSMUST00000124444.1
 Cend1
cell cycle exit and neuronal differentiation 1
chr11_-_6065538 21.660 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr11_+_67586675 21.654 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr12_+_29528382 21.638 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr5_+_117781017 21.509 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr2_+_170731807 21.260 ENSMUST00000029075.4
 Dok5
docking protein 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 320 entries
Log-likelihood per target Total log-likelihoodTermDescription
22.8 68.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
6.8 61.0 GO:0071420 cellular response to histamine(GO:0071420)
1.4 58.6 GO:0006376 mRNA splice site selection(GO:0006376)
14.6 43.9 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
1.7 43.7 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.2 42.3 GO:0030041 actin filament polymerization(GO:0030041)
1.6 39.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.9 36.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
4.5 36.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.2 35.0 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
1.8 32.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.7 32.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
4.0 31.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
5.3 31.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.6 27.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
6.4 25.4 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
1.8 23.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
2.6 23.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.2 22.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
7.5 22.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 106.9 GO:0016021 integral component of membrane(GO:0016021)
0.2 92.8 GO:0045202 synapse(GO:0045202)
11.4 68.3 GO:0097427 microtubule bundle(GO:0097427)
3.6 65.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4 52.2 GO:0005884 actin filament(GO:0005884)
1.0 47.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
4.8 47.7 GO:0044327 dendritic spine head(GO:0044327)
0.3 42.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.8 37.5 GO:0042734 presynaptic membrane(GO:0042734)
0.3 35.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 35.1 GO:0030427 site of polarized growth(GO:0030427)
1.8 34.9 GO:0032279 asymmetric synapse(GO:0032279)
1.0 33.2 GO:0032809 neuronal cell body membrane(GO:0032809)
1.5 30.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 29.5 GO:0005635 nuclear envelope(GO:0005635)
0.6 28.6 GO:0031594 neuromuscular junction(GO:0031594)
1.0 27.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.8 23.7 GO:0051233 spindle midzone(GO:0051233)
0.2 23.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
4.5 22.4 GO:0044316 cone cell pedicle(GO:0044316)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 235 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 73.5 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
3.1 52.3 GO:0004890 GABA-A receptor activity(GO:0004890)
1.1 44.2 GO:0005158 insulin receptor binding(GO:0005158)
2.4 40.5 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
1.4 39.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
2.1 37.1 GO:0035613 RNA stem-loop binding(GO:0035613)
1.3 36.5 GO:0030215 semaphorin receptor binding(GO:0030215)
5.3 31.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.8 29.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.5 29.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.6 28.0 GO:0070888 E-box binding(GO:0070888)
1.0 26.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 26.4 GO:0005543 phospholipid binding(GO:0005543)
0.7 25.8 GO:0030552 cAMP binding(GO:0030552)
0.7 25.6 GO:0050699 WW domain binding(GO:0050699)
1.2 25.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 24.9 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.8 24.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 24.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
7.4 22.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)