Motif ID: Ppard

Z-value: 0.642


Transcription factors associated with Ppard:

Gene SymbolEntrez IDGene Name
Ppard ENSMUSG00000002250.9 Ppard

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ppardmm10_v2_chr17_+_28232723_282327890.743.5e-13Click!


Activity profile for motif Ppard.

activity profile for motif Ppard


Sorted Z-values histogram for motif Ppard

Sorted Z-values for motif Ppard



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppard

PNG image of the network

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Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 10.528 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr15_+_25773985 7.462 ENSMUST00000125667.1
Myo10
myosin X
chr1_-_120120138 7.009 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr5_-_115119277 6.486 ENSMUST00000031524.7
Acads
acyl-Coenzyme A dehydrogenase, short chain
chr10_-_13324160 6.091 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr4_+_59581563 4.829 ENSMUST00000030078.5
Hsdl2
hydroxysteroid dehydrogenase like 2
chr4_+_59581645 4.501 ENSMUST00000107528.1
Hsdl2
hydroxysteroid dehydrogenase like 2
chrX_-_142306170 4.436 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr9_-_57262591 4.031 ENSMUST00000034846.5
1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr4_+_118429701 3.335 ENSMUST00000067896.3
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr5_+_110286306 3.187 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr4_+_98546710 3.107 ENSMUST00000102792.3
Inadl
InaD-like (Drosophila)
chr4_+_98546919 2.918 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr17_-_34028044 2.905 ENSMUST00000045467.7
ENSMUST00000114303.3
H2-Ke6

H2-K region expressed gene 6

chr3_-_79628660 2.697 ENSMUST00000120992.1
Etfdh
electron transferring flavoprotein, dehydrogenase
chr10_+_94147982 2.556 ENSMUST00000105290.2
Nr2c1
nuclear receptor subfamily 2, group C, member 1
chr9_-_51278540 2.477 ENSMUST00000114427.3
Gm684
predicted gene 684
chr5_-_31697598 2.436 ENSMUST00000031018.7
Rbks
ribokinase
chr11_+_70657687 2.431 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr5_+_129725063 2.174 ENSMUST00000086046.3
Gbas
glioblastoma amplified sequence

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.5 GO:0055114 oxidation-reduction process(GO:0055114)
0.8 10.5 GO:0042573 retinoic acid metabolic process(GO:0042573) positive regulation of collateral sprouting(GO:0048672)
0.1 7.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.3 7.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.4 7.0 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.7 6.5 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
1.1 4.4 GO:0099624 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.3 3.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 3.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 3.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.4 2.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.3 2.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 2.6 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 2.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 2.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 2.4 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.7 2.2 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.4 2.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 1.9 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.6 1.7 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 7.5 GO:0016459 myosin complex(GO:0016459)
0.3 7.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 6.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 6.0 GO:0005923 bicellular tight junction(GO:0005923)
1.5 5.9 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 3.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.6 3.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.2 2.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.5 2.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 1.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 1.3 GO:0031251 PAN complex(GO:0031251)
0.1 1.0 GO:0070552 BRISC complex(GO:0070552)
0.1 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.3 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
1.8 10.5 GO:0019841 retinol binding(GO:0019841)
0.4 7.7 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.1 7.5 GO:0030507 spectrin binding(GO:0030507)
1.8 7.0 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.9 4.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
1.3 3.9 GO:0048039 ubiquinone binding(GO:0048039)
0.3 3.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 3.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.4 2.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 2.7 GO:0009055 electron carrier activity(GO:0009055)
0.5 2.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 2.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.3 2.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 2.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 2.1 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.4 1.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.7 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)