Motif ID: Pparg_Rxrg

Z-value: 1.303

Transcription factors associated with Pparg_Rxrg:

Gene SymbolEntrez IDGene Name
Pparg ENSMUSG00000000440.6 Pparg
Rxrg ENSMUSG00000015843.4 Rxrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgmm10_v2_chr1_+_167598450_1675984800.132.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pparg_Rxrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_77894096 18.199 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr13_-_24761861 12.634 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr5_-_115119277 12.592 ENSMUST00000031524.7
Acads
acyl-Coenzyme A dehydrogenase, short chain
chr17_+_35049966 12.102 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr3_+_87948666 11.565 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr7_-_103843154 11.081 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr12_+_109452833 10.765 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr7_+_4925802 10.300 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr19_-_43912392 9.732 ENSMUST00000026209.4
Dnmbp
dynamin binding protein
chr4_+_126556935 8.766 ENSMUST00000048391.8
Clspn
claspin
chr11_-_100354040 8.429 ENSMUST00000173630.1
Hap1
huntingtin-associated protein 1
chr18_-_41951187 7.792 ENSMUST00000070949.4
Prelid2
PRELI domain containing 2
chr4_+_126556994 7.769 ENSMUST00000147675.1
Clspn
claspin
chr5_+_110286306 7.678 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr9_+_64117147 7.151 ENSMUST00000034969.7
Lctl
lactase-like
chr6_+_83137089 7.142 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr17_-_56290499 6.795 ENSMUST00000019726.6
Plin3
perilipin 3
chr2_-_26516620 6.732 ENSMUST00000132820.1
Notch1
notch 1
chr5_+_64970069 6.489 ENSMUST00000031080.8
Fam114a1
family with sequence similarity 114, member A1
chr13_+_108316332 6.127 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 385 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 32.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
6.1 18.2 GO:0006553 lysine metabolic process(GO:0006553)
2.1 16.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.8 13.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 12.0 GO:0008156 negative regulation of DNA replication(GO:0008156)
1.2 11.6 GO:0042573 retinoic acid metabolic process(GO:0042573)
2.2 11.1 GO:0015671 oxygen transport(GO:0015671)
0.3 10.5 GO:1902476 chloride transmembrane transport(GO:1902476)
1.5 10.4 GO:0016576 histone dephosphorylation(GO:0016576)
2.1 10.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.3 10.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 10.0 GO:0006446 regulation of translational initiation(GO:0006446)
3.0 9.0 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.2 8.5 GO:0015914 phospholipid transport(GO:0015914)
2.1 8.4 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.2 8.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.6 8.3 GO:0034501 protein localization to kinetochore(GO:0034501)
1.0 7.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.3 7.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.6 7.6 GO:0006000 fructose metabolic process(GO:0006000)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 160 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 33.6 GO:0005730 nucleolus(GO:0005730)
0.1 27.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 16.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 14.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 13.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 13.4 GO:0031012 extracellular matrix(GO:0031012)
0.1 12.6 GO:0005814 centriole(GO:0005814)
0.1 12.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
1.5 11.6 GO:0005833 hemoglobin complex(GO:0005833)
0.9 11.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 11.4 GO:0034707 chloride channel complex(GO:0034707)
2.8 11.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
2.1 10.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 8.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 8.4 GO:0000922 spindle pole(GO:0000922)
0.0 8.2 GO:0005694 chromosome(GO:0005694)
1.0 7.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.5 7.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 7.7 GO:0005903 brush border(GO:0005903)
0.1 7.5 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 266 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 33.8 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
4.5 18.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
2.8 16.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 15.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 14.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 14.0 GO:0005178 integrin binding(GO:0005178)
0.2 12.4 GO:0070491 repressing transcription factor binding(GO:0070491)
1.7 11.6 GO:0016918 retinal binding(GO:0016918)
2.8 11.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.9 11.1 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.5 10.2 GO:0001968 fibronectin binding(GO:0001968)
1.0 9.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 9.2 GO:0016504 peptidase activator activity(GO:0016504)
0.0 9.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 8.9 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.3 8.8 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 8.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.7 8.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 8.4 GO:0033613 activating transcription factor binding(GO:0033613)
1.3 7.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)