Motif ID: Prrx1_Isx_Prrxl1
Z-value: 0.680
Transcription factors associated with Prrx1_Isx_Prrxl1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Isx | ENSMUSG00000031621.3 | Isx |
| Prrx1 | ENSMUSG00000026586.10 | Prrx1 |
| Prrxl1 | ENSMUSG00000041730.7 | Prrxl1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Prrx1 | mm10_v2_chr1_-_163313661_163313710 | 0.69 | 4.3e-11 | Click! |
| Prrxl1 | mm10_v2_chr14_+_32599922_32599932 | -0.30 | 1.2e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 6.1 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 1.8 | 5.4 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) |
| 1.7 | 6.9 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 1.6 | 6.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 1.5 | 4.6 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.8 | 2.5 | GO:0006059 | hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401) |
| 0.8 | 2.3 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.8 | 2.3 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.7 | 2.9 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.7 | 2.1 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.7 | 2.0 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
| 0.7 | 2.0 | GO:0008228 | opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.6 | 2.2 | GO:0032439 | endosome localization(GO:0032439) |
| 0.5 | 3.8 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.5 | 2.1 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 0.5 | 1.6 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.5 | 4.1 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.5 | 2.6 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.5 | 1.5 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) |
| 0.5 | 1.4 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
| 0.4 | 2.6 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
| 0.4 | 5.3 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.4 | 2.0 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.4 | 0.8 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.4 | 2.8 | GO:0015840 | urea transport(GO:0015840) urea transmembrane transport(GO:0071918) |
| 0.4 | 3.4 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
| 0.3 | 3.0 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.3 | 2.3 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.3 | 0.7 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.3 | 1.3 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.3 | 1.5 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
| 0.3 | 12.8 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.3 | 9.6 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.3 | 1.1 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
| 0.3 | 0.8 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.3 | 3.3 | GO:0032367 | intracellular cholesterol transport(GO:0032367) |
| 0.3 | 5.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.2 | 2.9 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 0.2 | 1.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.2 | 0.7 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.2 | 0.9 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.2 | 1.9 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.2 | 1.3 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.2 | 2.2 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.2 | 1.5 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.2 | 2.0 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
| 0.2 | 0.9 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.2 | 0.9 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.2 | 0.5 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.2 | 0.3 | GO:0072008 | glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
| 0.2 | 0.6 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.2 | 1.1 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.1 | 1.0 | GO:0007343 | egg activation(GO:0007343) |
| 0.1 | 3.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 0.7 | GO:0033762 | response to glucagon(GO:0033762) |
| 0.1 | 0.4 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.1 | 0.4 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.1 | 1.6 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
| 0.1 | 0.5 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
| 0.1 | 0.8 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
| 0.1 | 0.7 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.1 | 1.6 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.1 | 0.3 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.1 | 0.4 | GO:0060690 | epithelial cell differentiation involved in salivary gland development(GO:0060690) |
| 0.1 | 2.8 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.1 | 0.4 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.1 | 0.5 | GO:0060161 | peptidyl-arginine omega-N-methylation(GO:0035247) positive regulation of dopamine receptor signaling pathway(GO:0060161) |
| 0.1 | 0.4 | GO:0043137 | DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 0.5 | GO:0046909 | intermembrane transport(GO:0046909) |
| 0.1 | 0.6 | GO:0002591 | positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) |
| 0.1 | 0.4 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
| 0.1 | 0.4 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.1 | 1.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.7 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 0.2 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
| 0.1 | 0.9 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.1 | 0.4 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.1 | 0.8 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.1 | 0.2 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.1 | 0.7 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 0.4 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 0.2 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 0.1 | 2.5 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
| 0.1 | 1.3 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 1.9 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
| 0.1 | 0.2 | GO:0042701 | progesterone secretion(GO:0042701) |
| 0.1 | 0.3 | GO:0046549 | retinal cone cell development(GO:0046549) |
| 0.1 | 1.4 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
| 0.0 | 1.0 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.0 | 0.8 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 0.0 | 0.4 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
| 0.0 | 0.3 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.0 | 0.1 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.0 | 0.4 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 1.1 | GO:0010883 | regulation of lipid storage(GO:0010883) |
| 0.0 | 0.3 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.0 | 0.4 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.0 | 0.4 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.0 | 0.2 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.0 | 0.5 | GO:0042517 | positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517) |
| 0.0 | 1.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.2 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 1.0 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 0.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.6 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
| 0.0 | 1.2 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.7 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.5 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.0 | 1.7 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 0.0 | 0.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.0 | 0.1 | GO:0045346 | regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.0 | 1.4 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.0 | 0.2 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.0 | 0.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.3 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.0 | 0.2 | GO:0043278 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.0 | 0.2 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) bone trabecula formation(GO:0060346) |
| 0.0 | 0.4 | GO:0010922 | positive regulation of phosphatase activity(GO:0010922) |
| 0.0 | 1.6 | GO:0050728 | negative regulation of inflammatory response(GO:0050728) |
| 0.0 | 0.6 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.0 | 0.1 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
| 0.0 | 0.2 | GO:1901409 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.0 | 0.8 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
| 0.0 | 0.4 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
| 0.0 | 0.3 | GO:0006337 | nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986) |
| 0.0 | 0.1 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.0 | 0.1 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
| 0.0 | 0.1 | GO:0030242 | pexophagy(GO:0030242) |
| 0.0 | 0.1 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
| 0.0 | 0.4 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.0 | 0.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 0.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.5 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.0 | 0.2 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 0.1 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.0 | 0.4 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
| 0.0 | 0.6 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.0 | 0.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.3 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.2 | GO:0042407 | cristae formation(GO:0042407) |
| 0.0 | 0.7 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 1.2 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.2 | GO:0009651 | response to salt stress(GO:0009651) |
| 0.0 | 1.8 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 1.8 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.0 | 0.2 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.0 | 0.1 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.6 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.0 | 0.0 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.0 | 0.5 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 1.0 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.0 | 0.9 | GO:0006974 | cellular response to DNA damage stimulus(GO:0006974) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 12.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 1.4 | 6.9 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.8 | 3.3 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.6 | 2.5 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.4 | 2.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.4 | 2.2 | GO:0045179 | apical cortex(GO:0045179) |
| 0.4 | 6.3 | GO:0043205 | fibril(GO:0043205) |
| 0.3 | 1.7 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.3 | 4.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.2 | 2.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.2 | 1.1 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 2.0 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.2 | 1.2 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.2 | 5.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 0.7 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 0.4 | GO:0031983 | vesicle lumen(GO:0031983) |
| 0.1 | 1.1 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 0.4 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 2.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 0.8 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 2.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.0 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.4 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 0.1 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.1 | 0.9 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.6 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.1 | 0.7 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.1 | 0.9 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.1 | 2.9 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 0.2 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 0.1 | 3.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.3 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 0.0 | 0.4 | GO:0030312 | external encapsulating structure(GO:0030312) |
| 0.0 | 0.5 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.4 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.3 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.2 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 2.4 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.2 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 0.2 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.0 | 1.8 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 0.1 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.0 | 0.2 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.5 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 1.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.6 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 0.1 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.0 | 0.1 | GO:0008623 | CHRAC(GO:0008623) |
| 0.0 | 0.2 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.3 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.1 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 0.3 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 2.4 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 0.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.5 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.5 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.5 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.0 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.0 | 0.5 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 2.7 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.3 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 3.1 | GO:0005667 | transcription factor complex(GO:0005667) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 12.8 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 1.3 | 6.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 1.0 | 6.9 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.5 | 5.3 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.5 | 2.0 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.5 | 2.9 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 0.5 | 1.4 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958) |
| 0.5 | 2.8 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.5 | 2.3 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.5 | 1.4 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.4 | 2.2 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.4 | 2.0 | GO:0071253 | connexin binding(GO:0071253) |
| 0.4 | 2.0 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.4 | 3.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.3 | 1.3 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.3 | 4.5 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.3 | 2.8 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.3 | 0.8 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.2 | 1.2 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.2 | 0.7 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
| 0.2 | 1.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.2 | 1.3 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.2 | 1.7 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.2 | 2.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.2 | 1.2 | GO:0019841 | retinol binding(GO:0019841) |
| 0.2 | 2.6 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.2 | 3.5 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.2 | 0.7 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.2 | 2.1 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.2 | 0.9 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.2 | 0.5 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
| 0.2 | 0.5 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.1 | 0.6 | GO:0015464 | acetylcholine receptor activity(GO:0015464) G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.8 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.1 | 0.8 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 1.2 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.1 | 0.6 | GO:0015440 | peptide-transporting ATPase activity(GO:0015440) |
| 0.1 | 0.5 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.1 | 1.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.1 | 0.8 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.1 | 6.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 0.7 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.9 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
| 0.1 | 0.3 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.1 | 2.1 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 1.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 0.9 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.1 | 1.9 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 0.9 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 2.2 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.1 | 1.1 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.1 | 2.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 3.6 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 0.3 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
| 0.1 | 4.3 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.1 | 1.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.4 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 0.4 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 0.7 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
| 0.1 | 1.1 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 0.4 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.1 | 0.6 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
| 0.1 | 3.2 | GO:0051287 | NAD binding(GO:0051287) |
| 0.1 | 4.3 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.2 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.0 | 12.2 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 1.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.4 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 2.3 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.4 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.8 | GO:0044653 | trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859) |
| 0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 5.2 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.6 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.8 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.0 | 0.2 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.0 | 0.4 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.0 | 1.0 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 0.7 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 0.6 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.9 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 1.1 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 1.1 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
| 0.0 | 0.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.1 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.0 | 3.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 1.0 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 1.6 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.3 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.0 | 0.6 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 1.3 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 1.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.2 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.8 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.1 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.0 | 0.8 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.7 | GO:0009055 | electron carrier activity(GO:0009055) |
| 0.0 | 0.0 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.0 | 0.4 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.0 | 0.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 0.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 2.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 1.6 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 2.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.4 | GO:0016751 | S-succinyltransferase activity(GO:0016751) |
| 0.0 | 0.6 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
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