Motif ID: Ptf1a
Z-value: 0.678
Transcription factors associated with Ptf1a:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Ptf1a | ENSMUSG00000026735.2 | Ptf1a |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 6.8 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.9 | 10.4 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.8 | 3.1 | GO:0010046 | arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046) |
| 0.7 | 7.5 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.5 | 1.1 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.4 | 2.7 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.4 | 1.5 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.3 | 1.0 | GO:2000409 | positive regulation of T cell extravasation(GO:2000409) |
| 0.3 | 1.5 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 0.3 | 2.7 | GO:0048199 | vesicle targeting, to, from or within Golgi(GO:0048199) |
| 0.3 | 1.0 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.2 | 0.9 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.2 | 2.4 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.2 | 1.3 | GO:0006004 | fucose metabolic process(GO:0006004) |
| 0.1 | 0.5 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 0.1 | 6.9 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
| 0.1 | 10.7 | GO:0048663 | neuron fate commitment(GO:0048663) |
| 0.1 | 1.0 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
| 0.1 | 0.8 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.1 | 0.4 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 1.1 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.1 | 0.3 | GO:0015886 | heme transport(GO:0015886) |
| 0.1 | 0.5 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.1 | 1.1 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.1 | 0.9 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.0 | 0.2 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.0 | 0.1 | GO:1903587 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) |
| 0.0 | 0.3 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
| 0.0 | 2.5 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 1.1 | GO:0045646 | regulation of erythrocyte differentiation(GO:0045646) |
| 0.0 | 0.5 | GO:0035767 | endothelial cell chemotaxis(GO:0035767) |
| 0.0 | 0.2 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.2 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 10.4 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.4 | 6.8 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.2 | 3.1 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.2 | 2.7 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.2 | 1.0 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.1 | 0.9 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.1 | 0.3 | GO:0031983 | vesicle lumen(GO:0031983) |
| 0.1 | 0.6 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 1.0 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 1.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 2.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 0.5 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.0 | 10.7 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.3 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 1.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 2.4 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 0.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.0 | 0.8 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 6.8 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.9 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 7.5 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 1.1 | 6.8 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.7 | 10.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.6 | 3.6 | GO:0019841 | retinol binding(GO:0019841) |
| 0.4 | 6.9 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.4 | 1.1 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.3 | 3.1 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.3 | 1.3 | GO:0042806 | fucose binding(GO:0042806) |
| 0.3 | 1.0 | GO:0035877 | death effector domain binding(GO:0035877) caspase binding(GO:0089720) |
| 0.2 | 0.9 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.1 | 0.5 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.1 | 1.0 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.1 | 2.7 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 2.7 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.1 | 0.4 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 1.0 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 0.3 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.1 | 0.9 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.1 | 0.6 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 1.1 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.1 | 1.1 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 0.8 | GO:0019215 | intermediate filament binding(GO:0019215) ribosomal small subunit binding(GO:0043024) |
| 0.1 | 0.9 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 1.3 | GO:0034945 | dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595) |
| 0.0 | 1.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.1 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.2 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.0 | 1.1 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 1.5 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.1 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 0.0 | 0.1 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.0 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
