Motif ID: Rad21_Smc3
Z-value: 0.838
Transcription factors associated with Rad21_Smc3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Rad21 | ENSMUSG00000022314.9 | Rad21 |
| Smc3 | ENSMUSG00000024974.10 | Smc3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Smc3 | mm10_v2_chr19_+_53600377_53600435 | -0.36 | 2.2e-03 | Click! |
| Rad21 | mm10_v2_chr15_-_51991679_51991760 | -0.14 | 2.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 7.8 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625) |
| 2.5 | 10.1 | GO:0032439 | endosome localization(GO:0032439) |
| 1.7 | 5.0 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
| 1.6 | 4.7 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 1.3 | 5.2 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 1.2 | 3.7 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 1.0 | 2.9 | GO:0002295 | T-helper cell lineage commitment(GO:0002295) evasion or tolerance of host defenses by virus(GO:0019049) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) positive regulation of mononuclear cell migration(GO:0071677) negative regulation of hyaluronan biosynthetic process(GO:1900126) regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005) |
| 0.9 | 2.6 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.7 | 2.2 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.7 | 2.2 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.7 | 2.0 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 0.6 | 1.8 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 0.6 | 3.0 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.6 | 2.9 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.6 | 2.9 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.5 | 1.6 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) |
| 0.5 | 1.6 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
| 0.5 | 1.5 | GO:0097461 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) |
| 0.5 | 2.5 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.5 | 1.4 | GO:0046061 | dATP catabolic process(GO:0046061) |
| 0.5 | 1.4 | GO:2000508 | MDA-5 signaling pathway(GO:0039530) regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510) |
| 0.5 | 1.9 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.5 | 1.4 | GO:0045404 | positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.5 | 2.7 | GO:0048702 | embryonic neurocranium morphogenesis(GO:0048702) |
| 0.4 | 4.5 | GO:0032825 | positive regulation of natural killer cell differentiation(GO:0032825) |
| 0.4 | 1.3 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
| 0.4 | 1.3 | GO:0033860 | regulation of NAD(P)H oxidase activity(GO:0033860) |
| 0.4 | 3.7 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.4 | 2.8 | GO:0000050 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
| 0.4 | 1.6 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.4 | 1.2 | GO:2000170 | positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
| 0.4 | 1.1 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.4 | 1.9 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.4 | 1.1 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
| 0.4 | 2.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.3 | 1.4 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.3 | 1.0 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.3 | 2.0 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.3 | 1.6 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.3 | 1.9 | GO:0046645 | positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) |
| 0.3 | 1.8 | GO:0032202 | telomere assembly(GO:0032202) |
| 0.3 | 1.8 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.3 | 1.7 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.3 | 1.4 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.3 | 1.1 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.3 | 0.8 | GO:0032493 | response to bacterial lipoprotein(GO:0032493) |
| 0.3 | 0.8 | GO:0090202 | transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 0.2 | 1.2 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.2 | 0.5 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.2 | 0.7 | GO:1902988 | negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of presynaptic membrane organization(GO:1901630) negative regulation of dendritic spine maintenance(GO:1902951) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139) |
| 0.2 | 0.7 | GO:2000983 | regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984) |
| 0.2 | 1.2 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
| 0.2 | 0.8 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 0.2 | 0.6 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.2 | 1.3 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.2 | 0.6 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.2 | 0.6 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.2 | 0.7 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.2 | 1.8 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
| 0.2 | 3.2 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
| 0.2 | 1.2 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.2 | 0.5 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.2 | 1.2 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) |
| 0.2 | 0.5 | GO:0010533 | regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) |
| 0.2 | 2.1 | GO:0001779 | natural killer cell differentiation(GO:0001779) |
| 0.2 | 1.1 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.1 | 1.2 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.1 | 0.6 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.1 | 1.0 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.1 | 0.8 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 0.4 | GO:0046104 | thymidine metabolic process(GO:0046104) deoxyribonucleoside catabolic process(GO:0046121) |
| 0.1 | 0.6 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
| 0.1 | 1.7 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.1 | 1.2 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
| 0.1 | 0.7 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.1 | 0.8 | GO:0001771 | immunological synapse formation(GO:0001771) optic nerve morphogenesis(GO:0021631) |
| 0.1 | 3.3 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 0.4 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.1 | 0.3 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.1 | 0.5 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.1 | 1.0 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.1 | 1.0 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.1 | 0.2 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.1 | 0.6 | GO:0016102 | retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) |
| 0.1 | 1.6 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.1 | 0.3 | GO:0071169 | establishment of protein localization to chromatin(GO:0071169) |
| 0.1 | 0.4 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.1 | 1.8 | GO:2000193 | positive regulation of fatty acid transport(GO:2000193) |
| 0.1 | 1.3 | GO:0033273 | response to vitamin(GO:0033273) |
| 0.1 | 0.4 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 0.1 | 3.4 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.1 | 0.7 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.1 | 0.5 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 0.1 | 1.1 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.1 | 0.5 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503) |
| 0.1 | 0.4 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
| 0.1 | 0.7 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.1 | 0.4 | GO:0036089 | cleavage furrow formation(GO:0036089) |
| 0.1 | 0.8 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 0.7 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 0.4 | GO:0090261 | positive regulation of inclusion body assembly(GO:0090261) |
| 0.1 | 0.5 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.1 | 0.4 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.1 | 2.3 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.1 | 1.0 | GO:0000469 | cleavage involved in rRNA processing(GO:0000469) |
| 0.1 | 0.6 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
| 0.1 | 0.3 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.1 | 2.3 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.1 | 0.9 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
| 0.1 | 4.7 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.1 | 0.5 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.1 | 0.6 | GO:0043206 | extracellular fibril organization(GO:0043206) |
| 0.1 | 2.6 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.1 | 0.6 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.1 | 0.7 | GO:0006183 | GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) |
| 0.1 | 1.2 | GO:0048535 | lymph node development(GO:0048535) |
| 0.1 | 2.0 | GO:0044550 | secondary metabolite biosynthetic process(GO:0044550) |
| 0.1 | 0.6 | GO:0032506 | cytokinetic process(GO:0032506) |
| 0.1 | 1.8 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.1 | 0.2 | GO:0042045 | epithelial fluid transport(GO:0042045) |
| 0.1 | 2.2 | GO:1903846 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.1 | 0.3 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) negative regulation of neutrophil activation(GO:1902564) |
| 0.1 | 0.4 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.1 | 0.3 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.1 | 0.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 0.2 | GO:1904729 | regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729) |
| 0.1 | 1.3 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.1 | 1.0 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.1 | 0.6 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.1 | 0.5 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) positive regulation of centrosome cycle(GO:0046607) |
| 0.1 | 0.6 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.1 | 2.1 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.1 | 0.3 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
| 0.1 | 0.5 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.1 | 0.3 | GO:0021559 | trigeminal nerve development(GO:0021559) |
| 0.1 | 0.4 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.1 | 0.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 0.8 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.1 | 0.2 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.1 | 0.3 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.0 | 0.8 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.0 | 0.5 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 0.3 | GO:0042226 | interleukin-6 biosynthetic process(GO:0042226) regulation of interleukin-6 biosynthetic process(GO:0045408) |
| 0.0 | 0.2 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 1.4 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
| 0.0 | 0.5 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.0 | 0.7 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.0 | 0.2 | GO:0070589 | cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554) |
| 0.0 | 0.6 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
| 0.0 | 2.1 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.7 | GO:0090201 | negative regulation of release of cytochrome c from mitochondria(GO:0090201) |
| 0.0 | 2.7 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.2 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.0 | 1.3 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
| 0.0 | 0.8 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.7 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.0 | 1.4 | GO:0043297 | apical junction assembly(GO:0043297) |
| 0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.0 | 0.6 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.9 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.0 | 0.1 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.0 | 0.1 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.0 | 0.2 | GO:0032364 | oxygen homeostasis(GO:0032364) |
| 0.0 | 0.2 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.0 | 1.6 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.1 | GO:0007227 | signal transduction downstream of smoothened(GO:0007227) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.0 | 0.5 | GO:0061000 | negative regulation of dendritic spine development(GO:0061000) |
| 0.0 | 0.6 | GO:0045620 | negative regulation of lymphocyte differentiation(GO:0045620) |
| 0.0 | 0.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 3.6 | GO:0046330 | positive regulation of JNK cascade(GO:0046330) |
| 0.0 | 0.6 | GO:0061036 | positive regulation of cartilage development(GO:0061036) |
| 0.0 | 1.4 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.0 | 0.5 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.0 | 0.2 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.0 | 0.5 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 0.3 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.0 | 1.0 | GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway(GO:2001238) |
| 0.0 | 0.2 | GO:0051409 | response to nitrosative stress(GO:0051409) |
| 0.0 | 0.7 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.0 | 0.1 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.0 | 1.7 | GO:0006959 | humoral immune response(GO:0006959) |
| 0.0 | 1.0 | GO:0042176 | regulation of protein catabolic process(GO:0042176) |
| 0.0 | 0.7 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.0 | 0.3 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.8 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 0.1 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.0 | 0.2 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.0 | 0.2 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.0 | 0.1 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.0 | 3.4 | GO:0051321 | meiotic cell cycle(GO:0051321) |
| 0.0 | 0.6 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 0.7 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 1.1 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 0.3 | GO:0070266 | necroptotic process(GO:0070266) |
| 0.0 | 0.3 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.3 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.0 | 0.1 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 1.0 | GO:0016575 | histone deacetylation(GO:0016575) |
| 0.0 | 0.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 0.1 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 1.9 | GO:0007219 | Notch signaling pathway(GO:0007219) |
| 0.0 | 0.3 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.3 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.0 | 0.1 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.1 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 0.6 | GO:0042384 | cilium assembly(GO:0042384) |
| 0.0 | 0.1 | GO:2001197 | positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.4 | GO:0033014 | porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014) |
| 0.0 | 0.1 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.0 | 0.3 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.1 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 1.1 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 1.5 | GO:0000082 | G1/S transition of mitotic cell cycle(GO:0000082) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 10.4 | GO:0045179 | apical cortex(GO:0045179) |
| 1.0 | 3.1 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
| 0.4 | 1.1 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 0.4 | 1.8 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.3 | 1.0 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.3 | 2.0 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
| 0.3 | 0.7 | GO:0071438 | integrin alpha3-beta1 complex(GO:0034667) invadopodium membrane(GO:0071438) |
| 0.3 | 1.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.3 | 2.6 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.3 | 1.6 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.2 | 1.2 | GO:0005861 | troponin complex(GO:0005861) |
| 0.2 | 0.7 | GO:0034679 | integrin alpha9-beta1 complex(GO:0034679) |
| 0.2 | 0.9 | GO:0097651 | phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
| 0.2 | 0.7 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.2 | 2.9 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.2 | 0.6 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.2 | 1.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.2 | 1.0 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.2 | 1.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.2 | 1.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.2 | 1.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.6 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 1.0 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 1.8 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 0.4 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.1 | 1.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 3.1 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.1 | 0.6 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 0.7 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 0.8 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.1 | 1.5 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 1.0 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 1.0 | GO:0070688 | MLL5-L complex(GO:0070688) |
| 0.1 | 1.8 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 1.7 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.1 | 1.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 2.4 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 1.0 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.1 | 1.5 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.1 | 2.2 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 1.0 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.1 | 5.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 2.1 | GO:0005921 | gap junction(GO:0005921) |
| 0.1 | 1.3 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.1 | 0.7 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 1.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 0.2 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 0.1 | 3.8 | GO:0005844 | polysome(GO:0005844) |
| 0.1 | 0.5 | GO:0070187 | telosome(GO:0070187) |
| 0.1 | 3.1 | GO:0043235 | receptor complex(GO:0043235) |
| 0.1 | 0.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.6 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 0.8 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 0.4 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.1 | 0.2 | GO:0031502 | dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502) |
| 0.1 | 0.6 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 1.0 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 1.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 0.6 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 0.2 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.1 | 4.2 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.1 | 0.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.3 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 1.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.5 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.8 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.0 | 0.4 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.8 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 3.2 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 1.8 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.0 | 1.4 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.8 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 0.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 1.4 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 0.2 | GO:0097361 | CIA complex(GO:0097361) |
| 0.0 | 1.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 6.9 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.8 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 5.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.0 | 7.2 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 1.9 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 0.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.1 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 0.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 0.2 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.0 | 1.9 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.9 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.2 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 0.1 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.0 | 0.6 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.2 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.0 | 0.7 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 0.2 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 0.0 | 0.1 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.2 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.3 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.3 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.0 | 0.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.6 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.1 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.6 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 4.2 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.4 | GO:0005814 | centriole(GO:0005814) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 7.8 | GO:0004454 | ketohexokinase activity(GO:0004454) |
| 1.0 | 5.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.9 | 3.7 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.7 | 2.9 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.5 | 2.1 | GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 0.5 | 2.1 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.5 | 1.6 | GO:0030362 | protein phosphatase type 4 regulator activity(GO:0030362) |
| 0.5 | 1.5 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.5 | 3.4 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.5 | 1.8 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.4 | 1.2 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.4 | 1.6 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.4 | 1.6 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
| 0.4 | 4.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.4 | 5.0 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.4 | 1.9 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.4 | 1.1 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 0.4 | 2.2 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.4 | 1.8 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.4 | 1.4 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.3 | 2.6 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.3 | 1.3 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.3 | 0.9 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 0.3 | 1.2 | GO:0070573 | tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573) |
| 0.3 | 1.6 | GO:0043426 | MRF binding(GO:0043426) |
| 0.2 | 7.2 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.2 | 0.7 | GO:0046911 | hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.2 | 4.4 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.2 | 0.6 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.2 | 1.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.2 | 0.6 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.2 | 1.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.2 | 0.6 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.2 | 0.7 | GO:0035473 | lipase binding(GO:0035473) |
| 0.2 | 2.8 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) |
| 0.2 | 0.7 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.2 | 1.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 2.0 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.1 | 2.3 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.1 | 2.0 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.1 | 1.0 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.1 | 1.7 | GO:0005536 | glucose binding(GO:0005536) |
| 0.1 | 0.8 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.1 | 0.8 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.1 | 0.9 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.1 | 3.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.8 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 2.5 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 2.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 6.1 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 0.6 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.1 | 0.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.4 | GO:0051747 | cytosine C-5 DNA demethylase activity(GO:0051747) |
| 0.1 | 1.6 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 0.3 | GO:0035651 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 0.1 | 0.2 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.1 | 1.0 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.1 | 0.3 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.1 | 0.5 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 3.0 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 1.1 | GO:0042556 | cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 0.1 | 1.4 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.1 | 0.3 | GO:0031755 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 0.1 | 0.5 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 0.8 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 0.7 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 2.0 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.1 | 0.8 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.1 | 0.6 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 1.8 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 0.3 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.1 | 0.6 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 2.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.1 | 0.8 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 2.2 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 1.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 0.5 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 0.5 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.1 | 0.4 | GO:0034916 | 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760) |
| 0.1 | 0.4 | GO:0002054 | nucleobase binding(GO:0002054) |
| 0.1 | 0.2 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 0.1 | 1.1 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.1 | 0.5 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.1 | 1.1 | GO:0023026 | MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026) |
| 0.1 | 0.8 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 0.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 0.8 | GO:0016653 | oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653) |
| 0.1 | 0.6 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.4 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.1 | 0.5 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.1 | 0.7 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 0.2 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.1 | 0.5 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.1 | 7.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 0.4 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 0.0 | 0.2 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.6 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.0 | 0.2 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.0 | 0.0 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.0 | 0.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.7 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.5 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.2 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.0 | 2.3 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 1.8 | GO:0016876 | ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 0.5 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.0 | 1.5 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 2.2 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.2 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
| 0.0 | 2.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 1.2 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) DNA-N1-methyladenine dioxygenase activity(GO:0043734) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
| 0.0 | 1.8 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 1.0 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 0.9 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 2.3 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.3 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.0 | 0.2 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.1 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.0 | 1.0 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 1.9 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.0 | 0.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 5.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.8 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.0 | 0.1 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.0 | 0.6 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 1.3 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.3 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.0 | 6.6 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 1.8 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.4 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.1 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.1 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.0 | 0.1 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.0 | 2.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 1.0 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.4 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 2.8 | GO:0008234 | cysteine-type peptidase activity(GO:0008234) |
| 0.0 | 0.2 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 1.5 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 1.4 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 1.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.2 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.1 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.0 | 1.0 | GO:0016835 | carbon-oxygen lyase activity(GO:0016835) |
| 0.0 | 0.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.0 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) |
| 0.0 | 0.7 | GO:0046983 | protein dimerization activity(GO:0046983) |
| 0.0 | 0.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.1 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.1 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 1.3 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.1 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 1.3 | GO:0051020 | GTPase binding(GO:0051020) |
| 0.0 | 1.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.3 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 0.7 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 1.5 | GO:0051015 | actin filament binding(GO:0051015) |
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