Motif ID: Rara

Z-value: 0.601


Transcription factors associated with Rara:

Gene SymbolEntrez IDGene Name
Rara ENSMUSG00000037992.10 Rara

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Raramm10_v2_chr11_+_98927785_989278180.235.7e-02Click!


Activity profile for motif Rara.

activity profile for motif Rara


Sorted Z-values histogram for motif Rara

Sorted Z-values for motif Rara



Network of associatons between targets according to the STRING database.



First level regulatory network of Rara

PNG image of the network

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Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_141599835 6.041 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
Fblim1



filamin binding LIM protein 1



chr13_+_94875600 4.858 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr3_-_54915867 3.702 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr12_+_87026564 3.307 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr4_+_150853919 2.427 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr2_+_169633517 2.364 ENSMUST00000109157.1
Tshz2
teashirt zinc finger family member 2
chr4_+_48045144 2.225 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr17_-_56133817 2.220 ENSMUST00000167545.1
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr17_+_34593388 2.157 ENSMUST00000174532.1
Pbx2
pre B cell leukemia homeobox 2
chr4_-_46991842 1.993 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr8_-_94876269 1.963 ENSMUST00000046461.7
Dok4
docking protein 4
chr4_+_32238950 1.669 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr11_+_98960412 1.645 ENSMUST00000107473.2
Rara
retinoic acid receptor, alpha
chr14_+_58070547 1.604 ENSMUST00000165526.1
Fgf9
fibroblast growth factor 9
chr12_-_108893197 1.589 ENSMUST00000161154.1
ENSMUST00000161410.1
Wars

tryptophanyl-tRNA synthetase

chr10_-_89257790 1.464 ENSMUST00000045601.7
Ano4
anoctamin 4
chr14_+_55618023 1.444 ENSMUST00000002395.7
Rec8
REC8 homolog (yeast)
chr11_-_5915124 1.423 ENSMUST00000109823.2
ENSMUST00000109822.1
Gck

glucokinase

chr14_-_16575456 1.308 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta
chr11_+_94629741 1.281 ENSMUST00000021239.6
Lrrc59
leucine rich repeat containing 59

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 5.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.8 2.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.8 2.3 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.7 2.2 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 2.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 2.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 2.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.5 1.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.5 1.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.6 GO:0060484 male sex determination(GO:0030238) lung-associated mesenchyme development(GO:0060484)
0.5 1.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.5 1.4 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 1.4 GO:0007141 male meiosis I(GO:0007141)
0.2 1.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 1.3 GO:0014003 oligodendrocyte development(GO:0014003)
0.2 1.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 1.0 GO:0048268 clathrin coat assembly(GO:0048268)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.4 2.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.3 1.4 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.3 GO:0014704 intercalated disc(GO:0014704)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.9 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.0 GO:0031005 filamin binding(GO:0031005)
0.1 4.8 GO:0022839 ion gated channel activity(GO:0022839)
0.3 2.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 2.4 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.3 2.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 2.0 GO:0005158 insulin receptor binding(GO:0005158)
0.5 1.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 1.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.1 1.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.0 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)