Motif ID: Rest

Z-value: 3.893


Transcription factors associated with Rest:

Gene SymbolEntrez IDGene Name
Rest ENSMUSG00000029249.9 Rest

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Restmm10_v2_chr5_+_77266196_77266232-0.581.8e-07Click!


Activity profile for motif Rest.

activity profile for motif Rest


Sorted Z-values histogram for motif Rest

Sorted Z-values for motif Rest



Network of associatons between targets according to the STRING database.



First level regulatory network of Rest

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_42255704 145.517 ENSMUST00000087123.5
 Golga7b
golgi autoantigen, golgin subfamily a, 7B
chrX_-_73869804 140.187 ENSMUST00000066576.5
ENSMUST00000114430.1
 L1cam

L1 cell adhesion molecule

chr18_-_31447383 90.784 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr6_-_121473630 83.873 ENSMUST00000046373.5
 Iqsec3
IQ motif and Sec7 domain 3
chr11_-_35798884 72.542 ENSMUST00000160726.2
 Fbll1
fibrillarin-like 1
chr15_-_76521902 71.012 ENSMUST00000164703.1
ENSMUST00000096365.3
 Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr9_+_40269430 65.671 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chr11_+_80477015 65.231 ENSMUST00000053413.10
ENSMUST00000147694.1
 Cdk5r1

cyclin-dependent kinase 5, regulatory subunit 1 (p35)

chr3_-_80802789 63.607 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_+_153031852 61.441 ENSMUST00000037235.6
 Xkr7
X Kell blood group precursor related family member 7 homolog
chr1_+_34579693 60.629 ENSMUST00000052670.8
 Amer3
APC membrane recruitment 3
chr9_+_40269202 57.965 ENSMUST00000114956.3
ENSMUST00000049941.5
 Scn3b

sodium channel, voltage-gated, type III, beta

chr4_+_101550411 57.249 ENSMUST00000094953.4
ENSMUST00000106933.1
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr9_+_40269273 56.485 ENSMUST00000176185.1
 Scn3b
sodium channel, voltage-gated, type III, beta
chr2_-_25319095 49.093 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
 Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr2_+_132781278 49.028 ENSMUST00000028826.3
 Chgb
chromogranin B
chr11_+_77930800 48.799 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr4_-_129121234 48.718 ENSMUST00000030572.3
 Hpca
hippocalcin
chr12_-_112511136 47.836 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr17_-_91092715 46.581 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr7_-_81493725 46.127 ENSMUST00000119121.1
 Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr11_+_74619594 45.443 ENSMUST00000100866.2
 E130309D14Rik
RIKEN cDNA E130309D14 gene
chr2_+_155775333 44.432 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chr7_-_81493883 43.502 ENSMUST00000082090.7
 Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr2_-_181314500 43.240 ENSMUST00000103045.3
 Stmn3
stathmin-like 3
chr3_-_89764581 42.752 ENSMUST00000029562.3
 Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr7_+_27653906 42.456 ENSMUST00000008088.7
 Ttc9b
tetratricopeptide repeat domain 9B
chr7_-_27396542 39.565 ENSMUST00000108363.1
 Sptbn4
spectrin beta, non-erythrocytic 4
chr12_+_102554966 39.265 ENSMUST00000021610.5
 Chga
chromogranin A
chr12_+_102949450 38.973 ENSMUST00000179002.1
 Unc79
unc-79 homolog (C. elegans)
chr9_+_108826320 36.884 ENSMUST00000024238.5
 Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chrX_+_7638674 36.793 ENSMUST00000128890.1
 Syp
synaptophysin
chr2_-_27142429 35.989 ENSMUST00000151224.2
 Fam163b
family with sequence similarity 163, member B
chr5_-_121009510 35.853 ENSMUST00000079204.5
 Rph3a
rabphilin 3A
chrX_-_20920911 35.785 ENSMUST00000081893.6
ENSMUST00000115345.1
 Syn1

synapsin I

chr13_-_54749627 35.582 ENSMUST00000099506.1
 Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr1_-_84696182 34.071 ENSMUST00000049126.6
 Dner
delta/notch-like EGF-related receptor
chr17_+_28575718 33.905 ENSMUST00000080780.6
 Lhfpl5
lipoma HMGIC fusion partner-like 5
chr5_+_137030275 33.507 ENSMUST00000041543.8
 Vgf
VGF nerve growth factor inducible
chr5_-_116591811 32.999 ENSMUST00000076124.5
 Srrm4
serine/arginine repetitive matrix 4
chr11_-_3774706 31.934 ENSMUST00000155197.1
 Osbp2
oxysterol binding protein 2
chr15_-_76722161 31.176 ENSMUST00000049956.4
 Lrrc24
leucine rich repeat containing 24
chr9_+_59578192 30.775 ENSMUST00000118549.1
ENSMUST00000034840.3
 Celf6

CUGBP, Elav-like family member 6

chr7_+_51621830 28.642 ENSMUST00000032710.5
 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr2_-_25319187 28.625 ENSMUST00000114312.1
 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr12_-_84698769 28.377 ENSMUST00000095550.2
 Syndig1l
synapse differentiation inducing 1 like
chr13_-_54749849 27.750 ENSMUST00000135343.1
 Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr13_+_54371340 27.233 ENSMUST00000026985.8
 Cplx2
complexin 2
chr9_-_57467985 24.386 ENSMUST00000046587.6
 Scamp5
secretory carrier membrane protein 5
chr11_+_102393403 23.568 ENSMUST00000107105.2
ENSMUST00000107102.1
ENSMUST00000107103.1
ENSMUST00000006750.7
 Rundc3a



RUN domain containing 3A



chr1_+_81077274 23.121 ENSMUST00000068275.5
ENSMUST00000113494.2
 Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr17_-_83631892 20.490 ENSMUST00000051482.1
 Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr15_-_11037968 19.151 ENSMUST00000058007.5
 Rxfp3
relaxin family peptide receptor 3
chr19_-_45046614 18.380 ENSMUST00000145391.1
 Pdzd7
PDZ domain containing 7
chr1_+_81077204 17.535 ENSMUST00000123720.1
 Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr7_+_122671401 16.227 ENSMUST00000182095.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr7_+_122671378 15.734 ENSMUST00000182563.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr13_-_56895737 15.447 ENSMUST00000022023.6
ENSMUST00000109871.1
 Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr9_+_104569671 14.627 ENSMUST00000057742.8
 Cpne4
copine IV
chr1_-_193035651 14.289 ENSMUST00000016344.7
 Syt14
synaptotagmin XIV
chr19_+_22139028 13.389 ENSMUST00000099569.2
ENSMUST00000087576.4
ENSMUST00000074770.5
 Trpm3


transient receptor potential cation channel, subfamily M, member 3


chr4_+_129136948 13.098 ENSMUST00000102600.3
 Fndc5
fibronectin type III domain containing 5
chr9_+_104569754 12.972 ENSMUST00000077190.6
 Cpne4
copine IV
chr7_+_63444741 12.551 ENSMUST00000058476.7
 Otud7a
OTU domain containing 7A
chr9_-_22085391 12.114 ENSMUST00000179422.1
ENSMUST00000098937.3
ENSMUST00000177967.1
ENSMUST00000180180.1
 Ecsit



ECSIT homolog (Drosophila)



chr16_-_37384915 10.691 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr6_+_117168535 10.274 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
 Cxcl12


chemokine (C-X-C motif) ligand 12


chr8_+_18846251 9.933 ENSMUST00000149565.1
ENSMUST00000033847.4
 Agpat5

1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)

chr12_-_70347536 8.284 ENSMUST00000110520.2
ENSMUST00000110522.2
ENSMUST00000167755.1
 Trim9


tripartite motif-containing 9


chr13_-_105054895 8.190 ENSMUST00000063551.5
 Rgs7bp
regulator of G-protein signalling 7 binding protein
chr2_-_180104463 7.026 ENSMUST00000056480.3
 Hrh3
histamine receptor H3
chr1_-_34579613 6.619 ENSMUST00000062557.3
 1700101I19Rik
RIKEN cDNA 1700101I19 gene
chr2_+_152143552 6.049 ENSMUST00000089112.5
 Tcf15
transcription factor 15
chr9_+_122117375 5.831 ENSMUST00000118886.1
 Snrk
SNF related kinase
chr6_+_113282302 4.981 ENSMUST00000041203.5
 Cpne9
copine family member IX
chr12_+_113140198 4.389 ENSMUST00000084882.4
 Crip2
cysteine rich protein 2
chr16_-_37384940 4.122 ENSMUST00000114781.1
ENSMUST00000114780.1
 Stxbp5l

syntaxin binding protein 5-like

chr8_+_69088646 4.026 ENSMUST00000006435.7
 Atp6v1b2
ATPase, H+ transporting, lysosomal V1 subunit B2
chr9_+_122117258 3.585 ENSMUST00000146832.1
ENSMUST00000139181.1
 Snrk

SNF related kinase

chr9_+_122117338 3.260 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
 Snrk


SNF related kinase


chr13_-_23991158 2.691 ENSMUST00000021770.7
 Scgn
secretagogin, EF-hand calcium binding protein
chr4_-_153482768 2.345 ENSMUST00000105646.2
 Ajap1
adherens junction associated protein 1
chr17_-_72603709 1.858 ENSMUST00000086639.4
 Alk
anaplastic lymphoma kinase
chr6_-_134887783 1.829 ENSMUST00000066107.6
 Gpr19
G protein-coupled receptor 19
chr17_-_25240112 1.536 ENSMUST00000038973.6
ENSMUST00000115154.4
 Gnptg

N-acetylglucosamine-1-phosphotransferase, gamma subunit

chr9_+_40873981 1.310 ENSMUST00000067375.3
 Bsx
brain specific homeobox
chr2_-_92401237 1.199 ENSMUST00000050312.2
 Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
chr1_-_162548484 0.633 ENSMUST00000028017.9
 Mettl13
methyltransferase like 13
chr15_-_75747922 0.468 ENSMUST00000062002.4
 Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
35.7 142.9 GO:0021586 pons maturation(GO:0021586)
20.0 180.1 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
16.2 48.7 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
14.5 72.5 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
14.4 43.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
14.3 42.8 GO:0001661 conditioned taste aversion(GO:0001661)
14.0 140.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
13.1 39.3 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
12.3 36.8 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
11.3 90.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
9.3 46.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
9.2 55.4 GO:0072318 clathrin coat disassembly(GO:0072318)
6.6 39.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
6.1 36.9 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
5.4 27.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
4.5 89.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
4.0 44.4 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
3.9 39.0 GO:0048149 behavioral response to ethanol(GO:0048149)
3.5 52.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
3.4 83.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
3.3 63.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
3.1 34.1 GO:0007220 Notch receptor processing(GO:0007220)
2.8 33.5 GO:0043084 penile erection(GO:0043084)
2.6 10.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
2.5 12.6 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
2.3 7.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
2.3 48.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
1.9 13.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.7 23.6 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
1.5 71.0 GO:2001222 regulation of neuron migration(GO:2001222)
1.5 19.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
1.5 30.8 GO:0071625 vocalization behavior(GO:0071625)
1.4 28.6 GO:0001504 neurotransmitter uptake(GO:0001504)
1.4 32.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.4 35.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.2 24.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
1.2 8.3 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.9 6.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.7 33.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.7 15.4 GO:0006828 manganese ion transport(GO:0006828)
0.6 42.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.5 1.5 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.5 5.0 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.4 31.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 35.8 GO:0099643 neurotransmitter secretion(GO:0007269) presynaptic process involved in chemical synaptic transmission(GO:0099531) signal release from synapse(GO:0099643)
0.4 40.7 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.4 14.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.3 31.9 GO:0007286 spermatid development(GO:0007286)
0.2 52.7 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.2 12.1 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.2 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.3 GO:0060056 mammary gland involution(GO:0060056)
0.1 4.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 20.5 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.1 9.9 GO:0006639 neutral lipid metabolic process(GO:0006638) acylglycerol metabolic process(GO:0006639)
0.1 14.3 GO:0006906 vesicle fusion(GO:0006906)
0.1 0.5 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 28.4 GO:0009607 response to biotic stimulus(GO:0009607)
0.0 1.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 5.9 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
21.7 65.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
19.4 77.7 GO:0044307 dendritic branch(GO:0044307)
11.3 180.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
9.1 72.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
8.1 89.6 GO:1904115 axon cytoplasm(GO:1904115)
7.9 39.3 GO:0042583 chromaffin granule(GO:0042583)
6.8 27.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
6.8 33.9 GO:0032426 stereocilium tip(GO:0032426)
6.6 39.6 GO:0008091 spectrin(GO:0008091)
6.1 18.4 GO:0002141 stereocilia ankle link(GO:0002141)
6.1 90.8 GO:0031045 dense core granule(GO:0031045)
4.9 48.7 GO:0044327 dendritic spine head(GO:0044327)
3.9 287.2 GO:0042734 presynaptic membrane(GO:0042734)
3.9 42.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
2.6 100.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
2.1 80.7 GO:0097440 apical dendrite(GO:0097440)
2.0 61.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
1.6 47.8 GO:0060077 inhibitory synapse(GO:0060077)
0.7 33.5 GO:0030667 secretory granule membrane(GO:0030667)
0.7 32.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.6 1.2 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.4 4.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 59.7 GO:0030141 secretory granule(GO:0030141)
0.3 15.4 GO:0005801 cis-Golgi network(GO:0005801)
0.3 20.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 34.1 GO:0005769 early endosome(GO:0005769)
0.2 54.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 218.7 GO:0005794 Golgi apparatus(GO:0005794)
0.1 8.3 GO:0008021 synaptic vesicle(GO:0008021)
0.1 42.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 149.2 GO:0005886 plasma membrane(GO:0005886)
0.1 13.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 169.8 GO:0016021 integral component of membrane(GO:0016021)
0.1 10.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 4.4 GO:0005938 cell cortex(GO:0005938)
0.0 2.7 GO:0031410 cytoplasmic vesicle(GO:0031410)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
28.0 140.2 GO:0033691 sialic acid binding(GO:0033691)
25.7 180.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
10.6 63.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
7.9 23.6 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
7.1 77.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
3.9 42.8 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
3.9 46.6 GO:0097109 neuroligin family protein binding(GO:0097109)
3.6 35.9 GO:0042301 phosphate ion binding(GO:0042301)
3.1 88.9 GO:0001786 phosphatidylserine binding(GO:0001786)
2.9 64.0 GO:0017075 syntaxin-1 binding(GO:0017075)
2.8 65.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
2.3 83.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.6 42.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.5 28.6 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
1.4 29.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.3 15.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
1.2 7.0 GO:0015464 acetylcholine receptor activity(GO:0015464)
1.2 60.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.1 34.1 GO:0005112 Notch binding(GO:0005112)
1.1 72.5 GO:0042054 histone methyltransferase activity(GO:0042054)
1.0 44.4 GO:0045296 cadherin binding(GO:0045296)
0.9 10.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.9 39.6 GO:0030507 spectrin binding(GO:0030507)
0.8 32.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.7 20.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.7 31.9 GO:0015485 cholesterol binding(GO:0015485)
0.7 14.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.6 62.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.5 12.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.5 57.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.5 35.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 9.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.4 1.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.4 19.2 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.3 14.8 GO:0019905 syntaxin binding(GO:0019905)
0.3 8.3 GO:0000149 SNARE binding(GO:0000149)
0.2 31.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.2 7.8 GO:0005179 hormone activity(GO:0005179)
0.2 12.1 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 33.0 GO:0003729 mRNA binding(GO:0003729)
0.1 36.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 48.7 GO:0003779 actin binding(GO:0003779)
0.1 13.4 GO:0005261 cation channel activity(GO:0005261)
0.1 1.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 12.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 4.0 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0 407.3 GO:0003674 molecular_function(GO:0003674)