Motif ID: Rest
Z-value: 3.893

Transcription factors associated with Rest:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Rest | ENSMUSG00000029249.9 | Rest |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Rest | mm10_v2_chr5_+_77266196_77266232 | -0.58 | 1.8e-07 | Click! |
Top targets:
Showing 1 to 20 of 89 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 60 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
20.0 | 180.1 | GO:0060373 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
35.7 | 142.9 | GO:0021586 | pons maturation(GO:0021586) |
14.0 | 140.2 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
11.3 | 90.8 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
4.5 | 89.6 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
3.4 | 83.9 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
14.5 | 72.5 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
1.5 | 71.0 | GO:2001222 | regulation of neuron migration(GO:2001222) |
3.3 | 63.6 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
9.2 | 55.4 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.2 | 52.7 | GO:0060828 | regulation of canonical Wnt signaling pathway(GO:0060828) |
3.5 | 52.3 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
2.3 | 48.8 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
16.2 | 48.7 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
9.3 | 46.6 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
4.0 | 44.4 | GO:0044331 | cell-cell adhesion mediated by cadherin(GO:0044331) |
14.4 | 43.2 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
14.3 | 42.8 | GO:0001661 | conditioned taste aversion(GO:0001661) |
0.6 | 42.5 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.4 | 40.7 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 36 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.9 | 287.2 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.2 | 218.7 | GO:0005794 | Golgi apparatus(GO:0005794) |
11.3 | 180.1 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.1 | 169.8 | GO:0016021 | integral component of membrane(GO:0016021) |
0.1 | 149.2 | GO:0005886 | plasma membrane(GO:0005886) |
2.6 | 100.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
6.1 | 90.8 | GO:0031045 | dense core granule(GO:0031045) |
8.1 | 89.6 | GO:1904115 | axon cytoplasm(GO:1904115) |
2.1 | 80.7 | GO:0097440 | apical dendrite(GO:0097440) |
19.4 | 77.7 | GO:0044307 | dendritic branch(GO:0044307) |
9.1 | 72.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
21.7 | 65.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
2.0 | 61.7 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.3 | 59.7 | GO:0030141 | secretory granule(GO:0030141) |
0.2 | 54.6 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
4.9 | 48.7 | GO:0044327 | dendritic spine head(GO:0044327) |
1.6 | 47.8 | GO:0060077 | inhibitory synapse(GO:0060077) |
3.9 | 42.8 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 42.5 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
6.6 | 39.6 | GO:0008091 | spectrin(GO:0008091) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 47 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 407.3 | GO:0003674 | molecular_function(GO:0003674) |
25.7 | 180.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
28.0 | 140.2 | GO:0033691 | sialic acid binding(GO:0033691) |
3.1 | 88.9 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
2.3 | 83.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
7.1 | 77.7 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
1.1 | 72.5 | GO:0042054 | histone methyltransferase activity(GO:0042054) |
2.8 | 65.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
2.9 | 64.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
10.6 | 63.6 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.6 | 62.5 | GO:0051219 | phosphoprotein binding(GO:0051219) |
1.2 | 60.6 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.5 | 57.2 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.1 | 48.7 | GO:0003779 | actin binding(GO:0003779) |
3.9 | 46.6 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
1.0 | 44.4 | GO:0045296 | cadherin binding(GO:0045296) |
3.9 | 42.8 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
1.6 | 42.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.9 | 39.6 | GO:0030507 | spectrin binding(GO:0030507) |
0.1 | 36.7 | GO:0008022 | protein C-terminus binding(GO:0008022) |