Motif ID: Rfx2_Rfx7
Z-value: 1.420
Transcription factors associated with Rfx2_Rfx7:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Rfx2 | ENSMUSG00000024206.8 | Rfx2 |
| Rfx7 | ENSMUSG00000037674.9 | Rfx7 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rfx7 | mm10_v2_chr9_+_72532214_72532271 | 0.27 | 2.2e-02 | Click! |
| Rfx2 | mm10_v2_chr17_-_56830916_56831008 | -0.12 | 3.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 17.5 | GO:0034441 | plasma lipoprotein particle oxidation(GO:0034441) |
| 1.1 | 4.3 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.8 | 3.3 | GO:1902512 | positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626) |
| 0.8 | 2.4 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.7 | 2.9 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.7 | 5.5 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.6 | 2.5 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
| 0.6 | 1.2 | GO:2000282 | regulation of cellular amino acid biosynthetic process(GO:2000282) |
| 0.5 | 4.9 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.5 | 2.1 | GO:0018307 | enzyme active site formation(GO:0018307) |
| 0.5 | 4.6 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.5 | 5.0 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 0.5 | 2.0 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.5 | 2.5 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
| 0.4 | 4.0 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
| 0.4 | 3.4 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.4 | 1.3 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
| 0.4 | 1.5 | GO:0097393 | post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582) |
| 0.4 | 2.9 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.4 | 3.6 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.3 | 1.9 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.3 | 7.0 | GO:0003341 | cilium movement(GO:0003341) |
| 0.3 | 2.8 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.3 | 1.8 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
| 0.3 | 1.2 | GO:0061428 | positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.3 | 1.4 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
| 0.3 | 1.7 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.2 | 2.0 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.2 | 0.7 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
| 0.2 | 1.0 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.2 | 1.6 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.2 | 1.6 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.2 | 1.3 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.2 | 2.8 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.2 | 0.8 | GO:0090148 | membrane fission(GO:0090148) |
| 0.2 | 1.0 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
| 0.2 | 1.4 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.2 | 1.0 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
| 0.2 | 1.3 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.2 | 0.9 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 0.2 | 1.3 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.2 | 0.7 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.2 | 1.1 | GO:0006046 | N-acetylglucosamine catabolic process(GO:0006046) |
| 0.2 | 0.7 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.2 | 1.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.2 | 2.1 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.2 | 17.5 | GO:0007631 | feeding behavior(GO:0007631) |
| 0.2 | 2.8 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.2 | 1.5 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.1 | 0.4 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.1 | 2.3 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.1 | 4.5 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 2.3 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.1 | 0.5 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.1 | 5.5 | GO:1901381 | positive regulation of potassium ion transmembrane transport(GO:1901381) |
| 0.1 | 0.5 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.1 | 0.5 | GO:1900451 | postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.1 | 1.9 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.1 | 1.2 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.1 | 1.7 | GO:0032620 | interleukin-17 production(GO:0032620) |
| 0.1 | 1.1 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606) |
| 0.1 | 0.3 | GO:1903061 | regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) |
| 0.1 | 0.1 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.1 | 0.4 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 0.6 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.1 | 0.5 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 0.1 | 3.4 | GO:1902850 | mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850) |
| 0.1 | 0.2 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.1 | 0.5 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 0.7 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 0.9 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.1 | 0.6 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.1 | 1.9 | GO:0033198 | response to ATP(GO:0033198) |
| 0.1 | 1.3 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
| 0.1 | 0.7 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 0.6 | GO:0071340 | skeletal muscle acetylcholine-gated channel clustering(GO:0071340) |
| 0.1 | 0.5 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.1 | 1.8 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
| 0.1 | 0.2 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
| 0.1 | 0.6 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 1.6 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.1 | 0.4 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 1.0 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 0.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.1 | 0.7 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.1 | 0.3 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.1 | 1.1 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.1 | 2.3 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.1 | 3.5 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
| 0.1 | 0.2 | GO:1904683 | regulation of metalloendopeptidase activity(GO:1904683) negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049) |
| 0.1 | 1.1 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.1 | 0.3 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.1 | 0.5 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.1 | 0.3 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
| 0.1 | 0.2 | GO:1902224 | cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224) |
| 0.1 | 1.8 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.1 | 0.4 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.1 | 0.6 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 0.3 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.0 | 1.1 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.0 | 1.3 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.0 | 0.2 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 0.0 | 3.2 | GO:0034620 | cellular response to unfolded protein(GO:0034620) |
| 0.0 | 0.5 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.0 | 0.5 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 0.2 | GO:1903441 | protein localization to ciliary membrane(GO:1903441) |
| 0.0 | 0.4 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
| 0.0 | 0.2 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.0 | 0.2 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.0 | 0.1 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.0 | 0.8 | GO:0002437 | inflammatory response to antigenic stimulus(GO:0002437) |
| 0.0 | 2.9 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 0.7 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 1.4 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.0 | 0.2 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.0 | 7.6 | GO:0050890 | cognition(GO:0050890) |
| 0.0 | 1.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.0 | 0.8 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.0 | 0.9 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.2 | GO:0043084 | penile erection(GO:0043084) |
| 0.0 | 0.1 | GO:0036451 | cap mRNA methylation(GO:0036451) |
| 0.0 | 1.6 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.0 | 0.6 | GO:0045047 | protein targeting to ER(GO:0045047) |
| 0.0 | 0.2 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.1 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.0 | 0.1 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.0 | 0.6 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 3.8 | GO:0051321 | meiotic cell cycle(GO:0051321) |
| 0.0 | 0.2 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.7 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.0 | 1.3 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 1.1 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.0 | 0.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.3 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 0.5 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.0 | 0.1 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.0 | 0.4 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.1 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.0 | 0.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 0.1 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
| 0.0 | 0.5 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.1 | GO:1901524 | regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525) |
| 0.0 | 1.9 | GO:0098780 | mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780) |
| 0.0 | 0.1 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
| 0.0 | 0.2 | GO:0006047 | UDP-N-acetylglucosamine metabolic process(GO:0006047) |
| 0.0 | 0.1 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.0 | 0.8 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.0 | 0.3 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
| 0.0 | 0.4 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.3 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.0 | 0.7 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.7 | GO:0036156 | inner dynein arm(GO:0036156) |
| 1.2 | 17.5 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.9 | 17.6 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.9 | 3.4 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.8 | 3.3 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
| 0.6 | 8.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.6 | 3.4 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.5 | 3.2 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 0.4 | 1.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.4 | 1.5 | GO:1990421 | subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707) |
| 0.4 | 4.9 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.3 | 2.8 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.3 | 2.4 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.2 | 0.7 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.2 | 3.6 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.2 | 2.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 3.0 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 5.5 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.2 | 0.5 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.2 | 1.7 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 1.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 17.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 1.7 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.1 | 0.4 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.1 | 0.7 | GO:0016011 | dystroglycan complex(GO:0016011) |
| 0.1 | 2.5 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 2.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 0.3 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
| 0.1 | 1.5 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.1 | 0.3 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.1 | 2.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 1.1 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.1 | 2.3 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.9 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 1.5 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.1 | 7.3 | GO:0031514 | motile cilium(GO:0031514) |
| 0.1 | 0.8 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 1.8 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.1 | 0.9 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.1 | 0.3 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 5.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 2.3 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
| 0.0 | 0.4 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 1.2 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 2.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.8 | GO:0045120 | pronucleus(GO:0045120) |
| 0.0 | 0.3 | GO:0042599 | lamellar body(GO:0042599) |
| 0.0 | 0.5 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 0.5 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.0 | 0.6 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.1 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
| 0.0 | 0.2 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 1.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.8 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.7 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.2 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.3 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 0.1 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.0 | 0.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.5 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.7 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 0.2 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.9 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 1.5 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 1.1 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.1 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.1 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 0.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 1.0 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.6 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 2.9 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.6 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 5.0 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.4 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.3 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.7 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.2 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 17.5 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499) |
| 1.2 | 3.5 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.7 | 3.4 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.7 | 2.0 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.7 | 3.3 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.6 | 2.5 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.5 | 1.4 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.4 | 8.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.4 | 1.7 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.4 | 2.1 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.4 | 2.5 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.4 | 1.6 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.3 | 1.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.3 | 1.6 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.3 | 2.5 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.3 | 1.2 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903) |
| 0.3 | 3.5 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.3 | 1.5 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.2 | 1.8 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.2 | 1.5 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.2 | 2.4 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.2 | 1.1 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
| 0.2 | 1.3 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.2 | 0.9 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.2 | 1.7 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.2 | 0.5 | GO:0043912 | D-lysine oxidase activity(GO:0043912) |
| 0.2 | 0.5 | GO:0005119 | smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108) |
| 0.1 | 1.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.7 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 1.3 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.1 | 2.3 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 0.5 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 2.1 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.1 | 0.3 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.1 | 1.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 1.1 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.1 | 0.4 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 0.7 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 5.2 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 1.9 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.1 | 1.8 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 1.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 3.1 | GO:0034945 | dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595) |
| 0.1 | 1.3 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 2.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 1.8 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.1 | 11.3 | GO:0003774 | motor activity(GO:0003774) |
| 0.1 | 0.2 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 0.7 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 1.2 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.1 | 5.3 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.1 | 4.9 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.1 | 1.1 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 13.5 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.1 | 2.0 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.1 | 1.3 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
| 0.1 | 0.7 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 1.7 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.1 | 0.4 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 0.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 0.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 0.2 | GO:0008410 | CoA-transferase activity(GO:0008410) |
| 0.1 | 0.7 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.1 | 0.5 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.0 | 0.3 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.0 | 0.8 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 1.7 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
| 0.0 | 0.3 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.2 | GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) |
| 0.0 | 0.8 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.1 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.0 | 1.3 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 1.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.4 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.0 | 1.0 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.0 | 0.4 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.0 | 0.7 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 1.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 2.8 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 0.8 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.8 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.1 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.0 | 1.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.5 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
| 0.0 | 0.1 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.0 | 0.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.5 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.0 | 0.5 | GO:0015925 | galactosidase activity(GO:0015925) |
| 0.0 | 0.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.1 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.0 | 0.2 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.0 | 0.6 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 0.7 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.0 | 2.0 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.0 | 0.9 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.7 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 0.1 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.0 | 1.4 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.0 | 2.9 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.1 | GO:0008796 | bis(5'-nucleosyl)-tetraphosphatase activity(GO:0008796) |
|
|
|