Motif ID: Rfx2_Rfx7

Z-value: 1.420

Transcription factors associated with Rfx2_Rfx7:

Gene SymbolEntrez IDGene Name
Rfx2 ENSMUSG00000024206.8 Rfx2
Rfx7 ENSMUSG00000037674.9 Rfx7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx7mm10_v2_chr9_+_72532214_725322710.272.2e-02Click!
Rfx2mm10_v2_chr17_-_56830916_56831008-0.123.3e-01Click!


Activity profile for motif Rfx2_Rfx7.

activity profile for motif Rfx2_Rfx7


Sorted Z-values histogram for motif Rfx2_Rfx7

Sorted Z-values for motif Rfx2_Rfx7



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx2_Rfx7

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_129960760 14.608 ENSMUST00000139884.1
 1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr2_-_21205342 11.166 ENSMUST00000027992.2
 Enkur
enkurin, TRPC channel interacting protein
chr8_+_116504973 6.809 ENSMUST00000078170.5
 Dynlrb2
dynein light chain roadblock-type 2
chr3_+_156562141 6.696 ENSMUST00000175773.1
 Negr1
neuronal growth regulator 1
chr3_+_156561792 6.026 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr18_+_75820174 5.517 ENSMUST00000058997.7
 Zbtb7c
zinc finger and BTB domain containing 7C
chr5_+_27261916 5.294 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr17_+_25471564 5.045 ENSMUST00000025002.1
 Tekt4
tektin 4
chr17_-_10840285 4.944 ENSMUST00000041463.6
 Pacrg
PARK2 co-regulated
chr17_+_43568269 4.706 ENSMUST00000024706.5
 Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_+_43568641 4.521 ENSMUST00000169694.1
 Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr3_+_156561950 4.518 ENSMUST00000041425.5
ENSMUST00000106065.1
 Negr1

neuronal growth regulator 1

chr8_+_39005880 4.477 ENSMUST00000169034.1
 Tusc3
tumor suppressor candidate 3
chr10_+_79669410 4.466 ENSMUST00000020552.5
 Tpgs1
tubulin polyglutamylase complex subunit 1
chr2_-_3419019 4.343 ENSMUST00000115084.1
ENSMUST00000115083.1
 Meig1

meiosis expressed gene 1

chr17_+_43568475 4.187 ENSMUST00000167418.1
 Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr12_-_40038025 4.152 ENSMUST00000101472.3
 Arl4a
ADP-ribosylation factor-like 4A
chr17_+_43568096 4.074 ENSMUST00000167214.1
 Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr5_+_30281377 4.045 ENSMUST00000101448.3
 Drc1
dynein regulatory complex subunit 1
chr2_-_3419066 4.001 ENSMUST00000115082.3
 Meig1
meiosis expressed gene 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.5 17.5 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.2 17.5 GO:0007631 feeding behavior(GO:0007631)
0.0 7.6 GO:0050890 cognition(GO:0050890)
0.3 7.0 GO:0003341 cilium movement(GO:0003341)
0.7 5.5 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 5.5 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.5 5.0 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.5 4.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.5 4.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 4.5 GO:0050873 brown fat cell differentiation(GO:0050873)
1.1 4.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 4.0 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 3.8 GO:0051321 meiotic cell cycle(GO:0051321)
0.4 3.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 3.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.4 3.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 3.4 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.8 3.3 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 3.2 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.7 2.9 GO:1904425 negative regulation of GTP binding(GO:1904425)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 84 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 17.6 GO:0097228 sperm principal piece(GO:0097228)
1.2 17.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 17.4 GO:0031225 anchored component of membrane(GO:0031225)
0.6 8.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 7.3 GO:0031514 motile cilium(GO:0031514)
0.2 5.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 5.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 5.0 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.4 4.9 GO:0097225 sperm midpiece(GO:0097225)
1.6 4.7 GO:0036156 inner dynein arm(GO:0036156)
0.2 3.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.9 3.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.6 3.4 GO:0000235 astral microtubule(GO:0000235)
0.8 3.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.5 3.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.2 3.0 GO:0031045 dense core granule(GO:0031045)
0.0 2.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 2.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 2.8 GO:0031209 SCAR complex(GO:0031209)
0.1 2.5 GO:0005605 basal lamina(GO:0005605)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 17.5 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.1 13.5 GO:0005516 calmodulin binding(GO:0005516)
0.1 11.3 GO:0003774 motor activity(GO:0003774)
0.4 8.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 5.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 5.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 4.9 GO:0030276 clathrin binding(GO:0030276)
1.2 3.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.3 3.5 GO:0031996 thioesterase binding(GO:0031996)
0.7 3.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.7 3.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 3.1 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 2.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.8 GO:0051117 ATPase binding(GO:0051117)
0.6 2.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.4 2.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 2.5 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.2 2.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 2.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)