Motif ID: Rfx5

Z-value: 0.633


Transcription factors associated with Rfx5:

Gene SymbolEntrez IDGene Name
Rfx5 ENSMUSG00000005774.6 Rfx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx5mm10_v2_chr3_+_94954075_949542260.066.5e-01Click!


Activity profile for motif Rfx5.

activity profile for motif Rfx5


Sorted Z-values histogram for motif Rfx5

Sorted Z-values for motif Rfx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 62 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_37376359 5.985 ENSMUST00000012587.3
 Kif11
kinesin family member 11
chr7_-_105752193 5.396 ENSMUST00000033184.4
 Tpp1
tripeptidyl peptidase I
chr17_+_34263209 5.172 ENSMUST00000040828.5
 H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr7_-_30664986 5.012 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chr17_+_35861318 4.590 ENSMUST00000074259.8
ENSMUST00000174873.1
 Nrm

nurim (nuclear envelope membrane protein)

chr7_-_45092130 4.218 ENSMUST00000148175.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr17_+_35861343 3.988 ENSMUST00000172931.1
 Nrm
nurim (nuclear envelope membrane protein)
chr7_+_46841475 3.958 ENSMUST00000147535.1
 Ldha
lactate dehydrogenase A
chr8_+_94214567 3.688 ENSMUST00000079961.6
 Nup93
nucleoporin 93
chr7_-_45091713 3.668 ENSMUST00000141576.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr11_-_3539228 3.382 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
 Smtn



smoothelin



chr5_+_139150211 3.303 ENSMUST00000026975.6
 Heatr2
HEAT repeat containing 2
chr1_-_183147461 3.072 ENSMUST00000171366.1
 Disp1
dispatched homolog 1 (Drosophila)
chr11_+_61505138 3.041 ENSMUST00000102657.3
 B9d1
B9 protein domain 1
chr2_+_122147680 2.998 ENSMUST00000102476.4
 B2m
beta-2 microglobulin
chr17_+_37270214 2.728 ENSMUST00000038580.6
 H2-M3
histocompatibility 2, M region locus 3
chr17_+_35379608 2.583 ENSMUST00000081435.4
 H2-Q4
histocompatibility 2, Q region locus 4
chr7_+_100537192 2.567 ENSMUST00000120454.1
 Coa4
cytochrome c oxidase assembly factor 4
chr17_+_35439155 2.567 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
 H2-Q7



histocompatibility 2, Q region locus 7



chr7_+_100537052 2.436 ENSMUST00000054310.3
 Coa4
cytochrome c oxidase assembly factor 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 6.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 5.4 GO:0043171 peptide catabolic process(GO:0043171)
1.3 5.2 GO:0002339 B cell selection(GO:0002339)
0.5 5.0 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 5.0 GO:0051225 spindle assembly(GO:0051225)
0.8 4.0 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3 3.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 3.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3 3.1 GO:0060539 diaphragm development(GO:0060539)
0.6 3.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 3.0 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.9 2.7 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.3 2.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 2.1 GO:0043486 histone exchange(GO:0043486)
0.4 1.7 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.5 1.5 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2 1.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.4 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 1.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.3 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 13.2 GO:0042611 MHC protein complex(GO:0042611)
0.0 9.2 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.5 8.6 GO:0005652 nuclear lamina(GO:0005652)
0.1 6.0 GO:0005876 spindle microtubule(GO:0005876)
0.6 5.0 GO:0070652 HAUS complex(GO:0070652)
0.1 5.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 4.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 3.7 GO:0005643 nuclear pore(GO:0005643)
0.2 3.0 GO:0036038 MKS complex(GO:0036038)
0.2 1.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.1 1.2 GO:0031528 microvillus membrane(GO:0031528)
0.3 1.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.9 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.9 GO:0005509 calcium ion binding(GO:0005509)
1.3 5.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.6 5.2 GO:0015643 toxic substance binding(GO:0015643)
0.4 5.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.0 4.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 3.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.0 3.0 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 3.0 GO:0001948 glycoprotein binding(GO:0001948)
0.2 2.3 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.3 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 2.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.7 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.6 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3 1.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)